Orthopedics News and Research RSS Feed - Orthopedics News and Research

CIP2A pathway involved in erlotinib response

CIP2A pathway involved in erlotinib response

Researchers have identified a novel mechanism, involving the cancerous inhibitor of protein phosphatase 2A pathway, which mediates the anti-tumour effects of erlotinib in non-small-cell lung cancer cells without epidermal growth factor receptor mutations. [More]
Mayo Clinic achieves Honor Roll status in U.S. News and World Report's top hospitals ranking

Mayo Clinic achieves Honor Roll status in U.S. News and World Report's top hospitals ranking

Mayo Clinic has achieved the highest honor in U.S. News and World Report's ranking of top hospitals. Mayo Clinic earned more number one rankings than any other provider, ranking number one or number two in 11 of the 12 specialties based on reputation, services and volumes, safety and clinical outcomes. [More]
Cedars-Sinai named to Honor Roll in America's Best Hospitals by U.S. News & World Report

Cedars-Sinai named to Honor Roll in America's Best Hospitals by U.S. News & World Report

With 12 medical specialties rated among the finest in the nation, Cedars-Sinai has been named to the Honor Roll in the 2014-15 issue of America's Best Hospitals by U.S. News & World Report. [More]
Inflammatory shift in long-standing bipolar disorder

Inflammatory shift in long-standing bipolar disorder

Patients with chronic bipolar disorder, but not those with schizophrenia, have a shift towards an M1 rather than an M2 macrophage response, research suggests. [More]
UH Case Medical Center named one of nation's top hospitals

UH Case Medical Center named one of nation's top hospitals

University Hospitals Case Medical Center has once again been named one of the nation's top hospitals, according to U.S. News & World Report's annual Best Hospitals rankings. UH Case Medical Center was ranked in all 12 methodology-ranked specialties for the third year in a row and in the Top 20 in four specialties - Cancer, Gastroenterology, Ear, Nose & Throat, and Orthopaedics. [More]
Study: People with mobility impairments under age 65 have higher rates of smoking

Study: People with mobility impairments under age 65 have higher rates of smoking

Researchers from The Miriam Hospital have found that people with mobility impairments under age 65 have significantly higher rates of smoking than those without mobility impairments. [More]
Depressed COPD patients have difficulty in sticking to pulmonary rehabilitation program

Depressed COPD patients have difficulty in sticking to pulmonary rehabilitation program

Researchers from The Miriam Hospital have found that people with Chronic obstructive pulmonary disease (COPD) who are also depressed have difficulty sticking to a pulmonary rehabilitation program. [More]
Doctors offer new minimally invasive system to treat patients with narrowed, failing aortic heart

Doctors offer new minimally invasive system to treat patients with narrowed, failing aortic heart

Doctors at the Orlando Health Heart Institute are offering a new minimally invasive system to treat patients with narrowed, failing aortic heart valves who are considered to be at high risk to undergo surgery. Orlando Health is the only hospital in Orlando currently offering the Medtronic CoreValve® System. [More]
Thyroxine may overcome mutated thyroid hormone receptor effects

Thyroxine may overcome mutated thyroid hormone receptor effects

Patients with a mutation in the thyroid hormone receptor α gene that affects both the thyroid hormone receptor α1 and α2 protein variants have similar characteristics to patients with mutations affecting only the α1 variant, report researchers. [More]
Seattle magazine names 36 EvergreenHealth physicians to "Top Doctors" list

Seattle magazine names 36 EvergreenHealth physicians to "Top Doctors" list

The latest issue of Seattle magazine names 36 physicians within the EvergreenHealth network to the publication's annual "Top Doctors" list. [More]
Genetic variants alter chance of sunitinib dose reduction

Genetic variants alter chance of sunitinib dose reduction

Scientists have identified genetic variants that reduce the likelihood of sunitinib dose reduction in patients with metastatic renal cell carcinoma. [More]
Covenant and Sartori medical centers deploy TRU-D SmartUVC superbug-slaying robot

Covenant and Sartori medical centers deploy TRU-D SmartUVC superbug-slaying robot

Wheaton Franciscan Healthcare-Iowa is the latest to deploy TRU-D SmartUVC, a 5-foot-5 germ-killing ultraviolet robot equipped with the only infection prevention data collection and reporting software on the market. TRU-D is now in use at Covenant Medical Center in Waterloo and Sartori Medical Center in Cedar Falls, Iowa. [More]

Stryker Corporation to acquire all assets of Small Bone Innovations for $375M

Small Bone Innovations, Inc. (SBi) today announced that Stryker Corporation will acquire substantially all the assets of SBi in an all cash transaction for up to $375 million. [More]
FDA grants Thermedx 510(k) clearance for optional fluid warming in arthroscopic, hysteroscopic procedures

FDA grants Thermedx 510(k) clearance for optional fluid warming in arthroscopic, hysteroscopic procedures

Thermedx, LLC, an innovative designer and manufacturer of "smart" surgical irrigation products, received FDA 510(k) clearance for optional fluid warming in arthroscopic and hysteroscopic procedures. [More]
New smartphone app can reduce sedentary behavior in obese adults

New smartphone app can reduce sedentary behavior in obese adults

Even individuals who exercise a lot can be at risk for health problems if they also spend a lot of time in sedentary behaviors, such as sitting. [More]
Auxilium Pharmaceuticals plans to merge with QLT

Auxilium Pharmaceuticals plans to merge with QLT

Auxilium Pharmaceuticals, Inc., a fully integrated specialty biopharmaceutical company, and QLT Inc., a Canadian-based biotechnology company focused on developing innovative orphan ophthalmology products, today announced that they have entered into a definitive agreement under which Auxilium plans to merge with QLT. [More]
Arcam receives order from DiSanto Technology for two Arcam Q10 systems

Arcam receives order from DiSanto Technology for two Arcam Q10 systems

Arcam, listed on NASDAQ OMX, has received an order for two Arcam Q10 systems from the strategic partner DiSanto Technology Inc. in the US. The systems will be used for manufacturing of orthopedic implants. [More]
Six-gene signature predicts survival after targeted therapy for NSCLC

Six-gene signature predicts survival after targeted therapy for NSCLC

The presence of a six-gene profile in the microRNA of patients with advanced non-squamous non-small-cell lung cancer predicts reduced survival likelihood after first-line treatment with targeted therapy followed by chemotherapy for disease progression, indicate research results. [More]
FGFR1 amplification predicts poor outcome in early-stage NSCLC

FGFR1 amplification predicts poor outcome in early-stage NSCLC

Amplification of fibroblast growth factor receptor 1 is associated with poor clinical outcome in patients with early-stage non-small-cell lung cancer, Swiss researchers report. [More]
SCLC tumours replicated in mice from patients' CTCs

SCLC tumours replicated in mice from patients' CTCs

Scientists have used circulating tumour cells taken from patients with small-cell lung cancer to grow explant tumours in mice that retain the original’s morphological and genetic characteristics. [More]