Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

First report of alternative lengthening of telomeres in human cancer subtypes

The first report of the presence of alternative lengthening of telomeres (ALT) in cancers arising from the bladder, cervix, endometrium, esophagus, gallbladder, liver, and lung was published today in The American Journal of Pathology. The presence of ALT in carcinomas can be used as a diagnostic marker and has implications for the development of anti-cancer drug therapies.

3 Sep 2011

Results of Aeterna Zentaris' AEZS-131 anticancer Erk inhibitor presented at ACS 2011 meeting

Aeterna Zentaris Inc. today announced that a poster on its novel orally active anticancer Erk inhibitor, which includes AEZS-131, was presented at the 242nd American Chemical Society National Meeting held at the Colorado Convention Center in Denver, Colorado.

30 Aug 2011

Zinc may act as tumor suppressor in commonist form of pancreatic cancer

The essential element zinc has been shown in a new study to be a likely tumor suppressor in the commonist form of pancreatic cancer, University of Maryland scientists report in the current issue of the journal Cancer Biology & Therapy.

26 Aug 2011

AMT total net loss decreases 7% to € 8.7 million for first half year of 2011

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, today reported its results for the first half year of 2011.

25 Aug 2011

Combination of exercise and metformin less effective for people with diabetes

It's common enough for researchers to look at the impacts of prescribed drugs on the body. And if you're a diabetes researcher who believes that exercise has great benefits for those with type 2 diabetes, you're hoping your research will show that. But when Normand Boul- looked at the dual impacts of exercise and metformin - two of the most commonly-prescribed modalities for glucose control - on that very outcome, the hoped-for double whammy wasn't the result.

20 Aug 2011

IU scientist to investigate salubrinal drug against osteoporosis

An Indiana University scientist studying human bone growth has received a $2.6 million grant from the U.S. Department of Defense to study a chemical compound with potential to fight osteoporosis and accelerate broken bone healing.

18 Aug 2011

Optical coherence tomography can distinguish between high and low risk pancreatic cysts

A team of researchers from four Boston-area institutions led by Nicusor Iftimia from Physical Sciences, Inc. has demonstrated for the first time that optical coherence tomography (OCT), a high resolution optical imaging technique that works by bouncing near-infrared laser light off biological tissue, can reliably distinguish between pancreatic cysts that are low-risk and high-risk for becoming malignant.

18 Aug 2011

Lighter smokers with two high-risk gene variations more likely to develop lung cancer

Smokers with variations in two specific genes have a greater risk of smoking more cigarettes, becoming more dependent on nicotine and developing lung cancer, a new study from the Centre for Addiction and Mental Health (CAMH) shows.

18 Aug 2011

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

Pancreatic cancer researchers at Thomas Jefferson University have shown, for the first time, that blocking a receptor of a key hormone in the renin-angiotensin system (RAS) reduces cancer cell growth by activating the enzyme AMPK to inhibit fatty acid synthase, the ingredients to support cell division.

11 Aug 2011

Nesfatin-1 protein may help reduce body weight and blood sugar

A newly-identified protein may hold the key to keeping appetite and blood sugar in check, according to a study by York University researchers.

10 Aug 2011

Transvaginal nephrectomy could increase rate of living donors for kidney transplants

Kidney transplant from a living donor, besides of being the best option for young people and those affected by particular conditions, results in increased organ survival and solves in part the organ shortage afflicting Spain since the mid-90 despite the high rate of cadaveric donation.

5 Aug 2011

FDA grants Orphan Drug Designation to Kamada's AAT product for type 1 diabetes

Kamada LTD., a bio-pharmaceutical company engaged in the development, manufacturing and marketing of specialty life-saving therapeutics, was granted an Orphan Drug Designation for its Alpha-1 Antitrypsin (AAT) product to treat type 1 diabetes.

5 Aug 2011

Boston Therapeutics files chewable metformin ANDA with FDA to treat diabetes

Boston Therapeutics, Inc., a public company registered with the SEC and a developer of diabetes therapeutics, today announced that it has submitted an Abbreviated New Drug Application (ANDA) for chewable metformin with the U.S. Food and Drug Administration.

4 Aug 2011

Intensive glycaemic control may negatively affect a person's quality of life

Research published in The Cochrane Library found that the risk of death and cardiovascular disease, such as stroke, was unchanged whether glucose control was intense or conventional.

1 Aug 2011

Viewpoints: Sanders on angry Americans; Sebelius on Md. exchanges; Samuelson: 'it's the elderly, stupid'

If the Republicans have their way, the entire burden of deficit reduction will be placed on the elderly, the sick, children and working families. In the midst of a horrendous recession that is already causing severe pain for average Americans, this approach is morally grotesque. ... The Reid plan is bad. The constantly shifting plan by House Speaker John Boehner is much worse. ... Those cuts would mean drastic reductions in Social Security, Medicare and Medicaid.

30 Jul 2011

New protein discovery could help develop intracellular biologic drugs

Permeon Biologics, a biopharmaceutical company pioneering a novel class of intracellular protein biologics, today announced the discovery of an entirely new class of naturally occurring human supercharged proteins called Intraphilins-.

29 Jul 2011

Customized surfaces help reveal protein clumping process linked with Alzheimer's, diabetes

When normal proteins form protein clumps in the body, then alarm bells start ringing. Such clumps, called "amyloids," are closely associated with Alzheimer's disease and type 2 diabetes, formerly called adult-onset diabetes.

29 Jul 2011

Houston-based Mattress Firm commits to support pancreatic cancer research

Mattress Firm, a leading specialty mattress retailer with more than 720 stores nationwide, is committed to supporting the fight against pancreatic cancer by raising funds for clinical trials through the Translational Genomics Research Institute (TGen) globalCure initiative.

29 Jul 2011

Combination drug regimen safe and effective for renal transplant patients

For the thousands of patients who receive kidney transplants in the United States each year, preventing organ rejection without compromising other aspects of health requires a delicate balance of medications.

29 Jul 2011

Amylin, Lilly and Alkermes submit reply to FDA complete response letter for BYDUREON

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced that the companies have submitted their reply to a complete response letter issued in October 2010 by the U.S. Food and Drug Administration (FDA) regarding BYDUREON™ (exenatide extended-release for injectable suspension), an investigational medication for type 2 diabetes.

28 Jul 2011

Pancreas News and Research

Further Reading

First report of alternative lengthening of telomeres in human cancer subtypes

Results of Aeterna Zentaris' AEZS-131 anticancer Erk inhibitor presented at ACS 2011 meeting

Zinc may act as tumor suppressor in commonist form of pancreatic cancer

AMT total net loss decreases 7% to € 8.7 million for first half year of 2011

Combination of exercise and metformin less effective for people with diabetes

IU scientist to investigate salubrinal drug against osteoporosis

Optical coherence tomography can distinguish between high and low risk pancreatic cysts

Lighter smokers with two high-risk gene variations more likely to develop lung cancer

Blocking type 2 receptor reduces PDA cell growth with the activation of AMPK enzyme

Nesfatin-1 protein may help reduce body weight and blood sugar

Transvaginal nephrectomy could increase rate of living donors for kidney transplants

FDA grants Orphan Drug Designation to Kamada's AAT product for type 1 diabetes

Boston Therapeutics files chewable metformin ANDA with FDA to treat diabetes

Intensive glycaemic control may negatively affect a person's quality of life

Viewpoints: Sanders on angry Americans; Sebelius on Md. exchanges; Samuelson: 'it's the elderly, stupid'

New protein discovery could help develop intracellular biologic drugs

Customized surfaces help reveal protein clumping process linked with Alzheimer's, diabetes

Houston-based Mattress Firm commits to support pancreatic cancer research

Combination drug regimen safe and effective for renal transplant patients

Amylin, Lilly and Alkermes submit reply to FDA complete response letter for BYDUREON

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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