Paraplegia News and Research RSS Feed - Paraplegia News and Research

Paraplegia is an impairment in motor or sensory function of the lower extremities. It is usually the result of spinal cord injury or a congenital condition such as spina bifida which affects the neural elements of the spinal canal.
Manipulation of signals in nervous system can enhance recovery after traumatic injury

Manipulation of signals in nervous system can enhance recovery after traumatic injury

Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. They also found that manipulating these signals can enhance the return of function. [More]
Exome sequencing improves speed, accuracy of neurogenetic disorder diagnosis

Exome sequencing improves speed, accuracy of neurogenetic disorder diagnosis

UCLA researchers have found that a state-of-the-art molecular genetic test greatly improves the speed and accuracy with which they can diagnose neurogenetic disorders in children and adults. The discovery could lead directly to better care for people with rare diseases like spinocerebellar ataxia, leukodsystrophy, spastic paraplegia and many other conditions. [More]
Deleting microRNA-155 prevents diet-induced obesity in female mice

Deleting microRNA-155 prevents diet-induced obesity in female mice

Researchers at The Ohio State University Wexner Medical Center seeking a way to combat the growing epidemic of obesity have found that deleting microRNA-155 in female mice prevents diet-induced obesity. [More]
Indego exoskeleton receives FDA certification for U.S. use

Indego exoskeleton receives FDA certification for U.S. use

The U.S. Food and Drug Administration (FDA) has given clearance to market and sell the powered lower-limb exoskeleton created by a team of Vanderbilt engineers and commercialized by the Parker Hannifin Corporation for both clinical and personal use in the United States. [More]
Hereditary spastic paraplegia characteristics unveiled

Hereditary spastic paraplegia characteristics unveiled

Researchers have detailed the characteristics of a large cohort of patients with hereditary spastic paraplegias. [More]
UAB study shows IL-37 protein suppresses inflammatory response after spinal cord injury

UAB study shows IL-37 protein suppresses inflammatory response after spinal cord injury

Spinal cord injuries cause severe functional disabilities in those who sustain them, including paraplegia or tetraplegia, depending on the scale of the injury. This is due to the degeneration of the spinal pathways that carry nerve signals from the brain to the different parts of the body and vice versa, resulting in loss of mobility and sensitivity underneath the injured area. [More]
Invitae announces dramatic expansion of genetic testing menu

Invitae announces dramatic expansion of genetic testing menu

Invitae Corporation (NYSE: NVTA), a genetic information company, has announced that it has more than doubled the size of its genetic testing platform to include more than 600 genes and will begin releasing the new content between now and the end of the year. Invitae is immediately expanding its menu with dozens of new test panels for hereditary cancer, cardiovascular, neuromuscular, pediatric and other rare disorders. [More]
Novel brain-computer interface technology allows paralyzed man to walk

Novel brain-computer interface technology allows paralyzed man to walk

Novel brain-computer interface technology created by University of California, Irvine researchers has allowed a paraplegic man to walk for a short distance. [More]
Mesenchymal stem cell exosomes offer hope in healing chronic wounds

Mesenchymal stem cell exosomes offer hope in healing chronic wounds

Dr. Badiavas’ research demonstrates how mesenchymal stem cell (MSC) exosomes, cell-derived vesicles that exist in biological fluids, function to repair non-healing wounds. [More]
UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers find therapeutic target for treatment of acute spinal cord injuries

UAB researchers have identified a therapeutic target for the treatment of acute spinal cord injuries. According to this research, conducted on mice, the administration of a drug that prevents loss of myelin - the insulating sheath around nerve fibres that allows signals to be transmitted - increases the mobility of the mice after an injury. [More]
Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

Project Spark to advance neuroprotective drug for schizophrenia-associated cognitive impairment

A public-private consortium led by the biotech Iproteos -based at Parc Científic de Barcelona (PCB)-, and comprised by the biopharmaceutical company Ascil-Biopharma, the Institute for Biomedical Research (IRB Barcelona), the Centre for Genomic Regulation (CRG) and the University of the Basque Country (UPV/EHU) has launched a project to advance the development of a new neuroprotective drug for the treatment of the cognitive impairment associated with schizophrenia and other mental disorders. [More]
Electrical stimulation technology can help SCI patients regain bladder control

Electrical stimulation technology can help SCI patients regain bladder control

When individuals suffer a spinal cord injury, paralysis is only a part of the major impact on quality of life. Often they also lose bladder control, which frequently causes infections that can lead to kidney damage. [More]
TSRI study points way to potential therapies for hereditary spastic paraplegia

TSRI study points way to potential therapies for hereditary spastic paraplegia

Scientists at The Scripps Research Institute have discovered that a gene mutation linked to hereditary spastic paraplegia, a disabling neurological disorder, interferes with the normal breakdown of triglyceride fat molecules in the brain. The TSRI researchers found large droplets of triglycerides within the neurons of mice modeling the disease. [More]

Researchers develop artificial connection from brain to legs by bypassing with computer interface

Gait disturbance in individuals with spinal cord injury is attributed to the interruption of neural pathways from brain to the spinal locomotor center, whereas neural circuits locate below and above the lesion maintain most of their functions. [More]
FDA clears ReWalk wearable robotic exoskeleton for home usage

FDA clears ReWalk wearable robotic exoskeleton for home usage

Exoskeleton leader ReWalk Robotics announced today that the U.S. Food and Drug Administration has cleared the company's ReWalk Personal System for use at home and in the community. ReWalk is a wearable robotic exoskeleton that provides powered hip and knee motion to enable individuals with Spinal Cord Injury (SCI) to stand upright and walk. [More]
FDA approves marketing of first motorized device for patients with spinal cord injuries

FDA approves marketing of first motorized device for patients with spinal cord injuries

The U.S. Food and Drug Administration today allowed marketing of the first motorized device intended to act as an exoskeleton for people with lower body paralysis (paraplegia) due to a spinal cord injury. [More]
HAL robot suit helps paraplegics

HAL robot suit helps paraplegics

For most paraplegic patients, being able to walk again remains a dream. The HAL robot suit can help them regain a certain degree of mobility and activity. An expert team at the Centre for Neurorobotic Movement Training (ZNB) in Bochum has been testing the exoskeleton that was originally developed in Japan since 2011. With excellent results. [More]
New potential treatment for paraplegic patients

New potential treatment for paraplegic patients

People with severe injuries to their spinal cord currently have no prospect of recovery and remain confined to their wheelchairs. Now, all that could change with a new treatment that stimulates the spinal cord using electric impulses. [More]
Study shows spinal stimulation therapy may have potential to change prognosis of people with paralysis

Study shows spinal stimulation therapy may have potential to change prognosis of people with paralysis

Four people with paraplegia are able to voluntarily move previously paralyzed muscles as a result of a novel therapy that involves electrical stimulation of the spinal cord, according to a study funded in part by the National Institutes of Health and the Christopher & Dana Reeve Foundation. [More]
UC San Diego researchers uncover causes for hereditary spastic paraplegia

UC San Diego researchers uncover causes for hereditary spastic paraplegia

In a study published in the January 31, 2014 issue of Science, an international team led by scientists at the University of California, San Diego School of Medicine report doubling the number of known causes for the neurodegenerative disorder known as hereditary spastic paraplegia. HSP is characterized by progressive stiffness and contraction of the lower limbs and is associated with epilepsy, cognitive impairment, blindness and other neurological features. [More]
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