Pathogen News and Research

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Study could lead to new, more effective treatments for urinary tract infections

Anyone who thinks scientists lead a glamorous, exciting life should talk to Jennifer Snyder, a graduate student at the University of Maryland’s School of Medicine.

25 Oct 2004

QIMR researchers have received a 5 year grant to develop a vaccine against Group A streptococcus

QIMR researchers have received a 5 year grant from the National Institutes of Health in the USA to develop a vaccine against Group A streptococcus. This extremely prestigious grant makes QIMR one of the most successful recipients of NIH funding in Australia.

18 Oct 2004

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

A team of University of Florida researchers has created tiny hybrid particles that can speedily root out even one isolated E. coli bacterium lurking in ground beef or provide a crucial early warning alarm for bacteria used as agents of bioterrorism and for early disease diagnosis.

11 Oct 2004

Discovery of a central memory form of helper T cells that can offer immunity to leishmaniasis

Researchers at the University of Pennsylvania have discovered a "central memory" form of "helper" T cells that can offer immunity to leishmaniasis, a disease that causes considerable death and disfigurement across the globe and has been found in U.S. military personnel returning from Afghanistan and Iraq.

8 Oct 2004

Significant progress in development of an animal model of smallpox that closely resembles human disease

Scientists have made significant progress in developing an animal model of smallpox that closely resembles human disease, which will be necessary for testing of future vaccines and potential treatments.

5 Oct 2004

First generation of human retinal cells in the laboratory from human embryonic stem cells

Some of these retinal tissues such as Retinal Pigment Epithelium (RPE) may provide a novel therapeutic strategy for such devastating diseases as macular degeneration, retinitis pigmentosa, and other retinal degenerative diseases.

23 Sep 2004

Streptococcus bacteria uses sword and shield to fight white blood cells

A single gene called cylE within the important bacterial pathogen Group B Streptococcus (GBS), controls two factors that act together as a “sword” and “shield” to protect the bacteria from the killing effects of the immune system’s white blood cells

21 Sep 2004

Scientists decipher genetic code of ancient pathogen that causes the horse disease

More than 2,400 years after Hippocrates, the Greek physician born in 460 BC first described the symptoms of glanders, scientists have deciphered the genetic code of the ancient pathogen that causes the horse disease: Burkholderia mallei.

20 Sep 2004

Global health is recurrently being threatened by new and re-emerging infectious diseases

Global health is recurrently being threatened by new and re-emerging infectious diseases. Examples of new and re-emerging infectious diseases include SARS (Severe Acute Respiratory Syndrome), new variant CJD (Creutzfeldt-Jakob Disease), avian flu and Ebola.

20 Sep 2004

Children with complications from acute sinusits may experience significant illness from their infection

Acute sinusitis is a common pediatric disorder, accounting for 21 percent of children’s antibiotic prescriptions.

17 Sep 2004

A new vector of malaria in Africa called Oveng form

Malaria affects around 600 million people in the world and leads to an annual death toll of over 2 million. It is the world’s most widespread parasitic disease.

16 Sep 2004

Missing genes may help explain why plague bacteria are so deadly

What makes the germ that causes plague so fearsomely lethal, while a close relative only produces digestive disorders and is rarely fatal?

10 Sep 2004

University of Utah gets patent approval relating to methods of rapid nucleic acid amplification

The U.S. Patent and Trademark Office has issued the University of Utah U.S. patent No. U.S. 6,787,338 (the '338 patent) relating to methods of rapid nucleic acid amplification.

8 Sep 2004

Streptococcal bacteria disrupts blood clotting to infect humans

University of Michigan researchers have captured a glimpse of the endless arms race between infectious agents and the human immune system in a bacterium that uses a mimic of a human blood-clotting enzyme to advance its infection.

27 Aug 2004

Diarrhea the leading cause of death among the developing world's children

To most people in the developed world, diarrhea is a nuisance. It means some discomfort and maybe a trip to the local pharmacy.

23 Aug 2004

Existing hepatitis drug could lead to the development of new drugs for the treatment of anthrax

Thanks to new screening tools, and some luck, researchers at the University of Chicago have discovered three unrelated compounds that inhibit the two toxins – edema factor and lethal factor -- that have made anthrax one of the most feared of potential bioterror agents.

21 Aug 2004

Scientists have successfully filmed individual cells migrating within a functioning lymph node

The researchers hope to gain a deeper understanding of how our immune system functions from their detailed study of lymph node processes.

17 Aug 2004

Hospital anti-infection strategy probably won't work

Hospital patients increasingly face tenacious bacterial infections because microbes found in hospitals acquire resistance to commonly prescribed antibiotics. A recent strategy alternating the most commonly used antibiotics has sparked hope of stopping the spread of antibiotic resistance.

9 Aug 2004

Potential of genomics in disease research yet to be realized

Over the past decade genomics has revolutionized our understanding of how microorganisms cause disease. However, genomic studies need to be extended to a more diverse array of microorganisms and research tools improved to gain additional insights into pathogenesis, according to a new report released by the American Academy of Microbiology.

5 Aug 2004

New glycan arrays discover autoimmunogenic activities of SARS-CoV

Researchers in New York City and Guangzhou, China applied the rapidly-developing carbohydrate microarray technology to study an inactivated SARS-coronavirus (SARS-CoV) vaccine and discovered autoimmunogenic activity of this newly identified human viral pathogen.

2 Aug 2004