Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Long COVID's hidden toll: How does post-exertional malaise affect skeletal muscles?

Study investigates the pathophysiology of post-exertional malaise in long COVID patients, revealing skeletal muscle changes, exercise capacity reduction, metabolic disturbances, and tissue alterations.

8 Jan 2024

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

The current evidence of the role of gut microbiota in Alzheimer’s disease (AD) pathogenesis.

8 Jan 2024

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment.

5 Jan 2024

Seizures may be responsible for some sudden deaths in children, study finds

In a study designed to better understand sudden, unexpected deaths in young children, which usually occur during sleep, researchers have identified brief seizures, accompanied by muscle convulsions, as a potential cause.

4 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

Unmasking the persistent threats of long-COVID's pulmonary sequelae

A collaborative study led by Dr. Estefanía Nova-Lamperti of the Universidad de Concepción, Dr. Gonzalo Labarca of Harvard University, and Mauricio Hernández, of MELISA Institute, and which included the participation of researchers from leading academic institutions, sought to identify the sequelae associated with long-term pulmonary dysfunction (L-PDD) in patients with COVID-19.

4 Jan 2024

PharmaKure granted MHRA Clinical Trial Authorisation (CTA) for PK051 for the treatment of mild cognitive impairment due to Alzheimer’s Disease

Clinical Trial Authorisation application granted for combined drug PK051 targeting amyloid deposits associated with Alzheimer’s Disease.

From PharmaKure 4 Jan 2024

Could your diet impact endometriosis? Research points to dietary insights for treatment

The role of dietary ingredients in modifying the progression and development of endometriosis.

4 Jan 2024

Simple technique boosts antibody delivery for treating brain diseases

The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors.

3 Jan 2024

Research could offer a new approach to treating malnourished, stunted kids

Millions of children in under-resourced parts of the world suffer from malnutrition and, consequently, stunted growth.

3 Jan 2024

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

An atomic-level investigation of how Eastern equine encephalitis virus binds to a key receptor and gets inside of cells also has enabled the discovery of a decoy molecule that protects against the potentially deadly brain infection, in mice.

3 Jan 2024

Study maps gene network orchestrating complex process of IgG glycosylation in aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Mapping of the gene network that regulates glycan clock of ageing."

3 Jan 2024

Previously unidentified protein variant shields against Parkinson's disease

A previously unidentified genetic mutation in a small protein provides significant protection against Parkinson's disease and offers a new direction for exploring potential treatments, according to a new USC Leonard Davis School of Gerontology study.

2 Jan 2024

New AI tool spotlights hidden cancers for better diagnosis

A new artificial intelligence tool that interprets medical images with unprecedented clarity does so in a way that could allow time-strapped clinicians to dedicate their attention to critical aspects of disease diagnosis and image interpretation.

2 Jan 2024

Healthy aging modulates the neural oscillatory dynamics serving working memory function

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 24, entitled, "Age-related alterations in the oscillatory dynamics serving verbal working memory processing."

2 Jan 2024

Study identifies α-MSH as therapeutic candidate for corneal endothelial disease

Findings from a pioneering study in The American Journal of Pathology, published by Elsevier, reveal that administration of the neuropeptide α-melanocyte-stimulating hormone (α-MSH) promotes corneal healing and restores normal eye function to an otherwise degenerating and diseased cornea by providing protection against cell death and promoting cell regeneration.

2 Jan 2024

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a therapeutic window.

2 Jan 2024

Angelica gigas extract emerges as a potential treatment for vascular disease

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Angelica gigas extract inhibits acetylation of eNOS via IRE1α sulfonation/RIDD-SIRT1-mediated posttranslational modification in vascular dysfunction."

28 Dec 2023

Common inflammation pathway turns anthrax toxin into killer

Bacillus anthracis lethal toxin (LT) is a determinant of lethal anthrax. Its function in myeloid cells is required for bacterial dissemination, and LT itself can directly trigger dysfunction of the cardiovascular system.

26 Dec 2023

Increased β-amyloid accumulation may be linked to Alzheimer’s dementia risk in oldest of the old

A new study indicates that severity of amyloid deposition in the brain -; not just age -; may be key to determining who will benefit from new anti-amyloid therapies to delay the progression of Alzheimer's disease.

26 Dec 2023

Pathology News and Research

Further Reading

Long COVID's hidden toll: How does post-exertional malaise affect skeletal muscles?

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Seizures may be responsible for some sudden deaths in children, study finds

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Unmasking the persistent threats of long-COVID's pulmonary sequelae

PharmaKure granted MHRA Clinical Trial Authorisation (CTA) for PK051 for the treatment of mild cognitive impairment due to Alzheimer’s Disease

Could your diet impact endometriosis? Research points to dietary insights for treatment

Simple technique boosts antibody delivery for treating brain diseases

Research could offer a new approach to treating malnourished, stunted kids

Eastern equine encephalitis virus study uncovers decoy molecule that protects against deadly brain infection

Study maps gene network orchestrating complex process of IgG glycosylation in aging

Previously unidentified protein variant shields against Parkinson's disease

New AI tool spotlights hidden cancers for better diagnosis

Healthy aging modulates the neural oscillatory dynamics serving working memory function

Study identifies α-MSH as therapeutic candidate for corneal endothelial disease

Small molecule-switchable RNA platform enables control of therapeutic protein expression

Angelica gigas extract emerges as a potential treatment for vascular disease

Common inflammation pathway turns anthrax toxin into killer

Increased β-amyloid accumulation may be linked to Alzheimer’s dementia risk in oldest of the old

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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