Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Scientists identify new algorithm to distinguish two subtypes of malignant melanoma

Scientists of the University of Ulm and Columbia University have discovered a diagnostic algorithm to distinguish two subtypes of malignant melanoma. Desmoplastic and spindle cell melanoma may look alike - they often resemble little scars or retractions of the skin - but differ in prognosis and therapeutic options.

4 Nov 2013

Gene sequencing reveals mutations in estrogen receptor

Researchers at the University of Michigan Comprehensive Cancer Center have identified a type of mutation that develops after breast cancer patients take anti-estrogen therapies. The mutations explain one reason why patients often become resistant to this therapy.

4 Nov 2013

LMU researchers identify a factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

4 Nov 2013

Simulation-based team training improves patient safety and clinical outcomes

A study conducted by an inter-professional team of LSU Health Sciences Center New Orleans faculty found that simulation-based operating room team training of medical and nursing students resulted in more effective teamwork by improving attitudes, behaviors, interaction and overall performance leading to potential increased patient safety and better clinical outcomes.

4 Nov 2013

Study: Dual-pronged strategy could successfully treat childhood cancer

A dual-pronged strategy using two experimental cancer drugs together could successfully treat a childhood cancer by inhibiting tumour growth and blocking off the escape routes it uses to become resistant to treatment, finds a new study.

3 Nov 2013

Prana's PBT2 effective in reversing memory, learning losses associated with aging process

Prana Biotechnology, a leading global developer of first-in-class treatments for neurodegenerative disease, has today announced the publication of an article in the peer reviewed Aging Cell showing the effects of PBT2 on neurogenesis and in reversing the memory and learning losses associated with the aging process, in normal (ie non transgenic) old mice.

31 Oct 2013

New finding could help lead to better treatments for eczema

For the millions of people suffering from the intensely red, horribly itchy skin condition known as eczema, the only thing more maddening than their disease is the lack of understanding of what causes it, or makes it flare up from time to time.

31 Oct 2013

Reduced SMG1 protein expression may contribute to neurological disorders

The absence of a protein called SMG1 could be a contributing factor in the development of Parkinson's disease and other related neurological disorders, according to a study led by the Translational Genomics Research Institute.

31 Oct 2013

Canadian researchers contribute to the science of verotoxigenic E. coli and associated infections

Many Canadian scientists and clinicians were unsung heroes during the early years (1977-1983) of research unfolding around verotoxigenic E. coli (VTEC).

30 Oct 2013

Overweight men diagnosed with prostate cancer more likely to die from the disease

Men who are overweight or obese when they are diagnosed with prostate cancer are more likely to die from the disease than men who are of healthy weight, according to a Kaiser Permanente study published today in the journal Obesity Research & Clinical Practice. In patients with more aggressive forms of prostate cancer, the researchers also found an even stronger correlation between obesity and mortality.

30 Oct 2013

New research reveals iron deposits in brain play a role in pathology of MS

While it's been known for over a century that iron deposits in the brain play a role in the pathology of Multiple Sclerosis (MS), new imaging research from Western University (London, Canada) helps to answer the question of whether these accumulations are a cause or consequence of the disease.

29 Oct 2013

African-American women less likely to benefit from HPV vaccines to prevent cervical cancer

Two subtypes of human papillomavirus prevented by vaccines are half as likely to be found in African-American women as in white women with precancerous cervical lesions, according to researchers at Duke Medicine.

29 Oct 2013

Research findings could help define new vaccination applications

New research from the Masonic Cancer Center, University of Minnesota, and the University of Minnesota Center for Immunology has identified key proteins that influence immune response strategies, a finding that could influence new vaccination approaches.

29 Oct 2013

Two related genes underlie development of two rare bone tumours in nearly 100% of patients

Scientists have made a rare discovery that allows them to attribute two types of tumour almost entirely to specific mutations that lie in two related genes.

28 Oct 2013

NHMRC awards over $6M for Griffith University research projects

Griffith University research projects have been awarded just over $6m in research funding by the prestigious National Health and Medical Research Council.

28 Oct 2013

Men treated by self-referring urologists more likely to undergo unnecessary IMRT

A comprehensive review of Medicare claims for more than 45,000 patients from 2005 through 2010 found that nearly all of the 146 percent increase in intensity-modulated radiation therapy (IMRT) for prostate cancer among urologists with an ownership interest in the treatment was due to self-referral, according to new research, "Urologists' Use of Intensity-Modulated Radiation Therapy for Prostate Cancer," released today in The New England Journal of Medicine (NEJM) for its October 24, 2013 issue.

25 Oct 2013

Use of IMRT for prostate cancer doubles when self-referral's financial incentives involved

A comprehensive review of Medicare claims for more than 45,000 patients from 2005 through 2010 found that nearly all of the 146 percent increase in intensity-modulated radiation therapy for prostate cancer among urologists with an ownership interest in the treatment was due to self-referral, according to new research, "Urologists' Use of Intensity-Modulated Radiation Therapy for Prostate Cancer," released today in The New England Journal of Medicine for its October 24, 2013 issue.

25 Oct 2013

Study: Gene Expression Classifier test reduces unnecessary surgeries in thyroid nodule assessment

The latest study co-led by a CU School of Medicine researcher has confirmed that a Gene Expression Classifier (GEC) test can drastically reduce the problem of unnecessary surgeries in thyroid nodule assessment.

25 Oct 2013

Diabetic patients may require higher doses of metformin to achieve same anti-cancer activity

A University of Colorado Cancer Center study published online this month in the journal Cell Cycle shows that breast cancer cell growth, motility and aggression is promoted by excess glucose, as experienced by patients with diabetes and metabolic syndrome.

25 Oct 2013

Just 13 days in space may cause changes in eye structure, gene expression

Just 13 days in space may be enough to cause profound changes in eye structure and gene expression, report researchers from Houston Methodist, NASA Johnson Space Center, and two other institutions in the October 2013 issue of Gravitational and Space Research.

25 Oct 2013

Pathology News and Research

Further Reading

Scientists identify new algorithm to distinguish two subtypes of malignant melanoma

Gene sequencing reveals mutations in estrogen receptor

LMU researchers identify a factor that promotes metastasis of colon tumors

Simulation-based team training improves patient safety and clinical outcomes

Study: Dual-pronged strategy could successfully treat childhood cancer

Prana's PBT2 effective in reversing memory, learning losses associated with aging process

New finding could help lead to better treatments for eczema

Reduced SMG1 protein expression may contribute to neurological disorders

Canadian researchers contribute to the science of verotoxigenic E. coli and associated infections

Overweight men diagnosed with prostate cancer more likely to die from the disease

New research reveals iron deposits in brain play a role in pathology of MS

African-American women less likely to benefit from HPV vaccines to prevent cervical cancer

Research findings could help define new vaccination applications

Two related genes underlie development of two rare bone tumours in nearly 100% of patients

NHMRC awards over $6M for Griffith University research projects

Men treated by self-referring urologists more likely to undergo unnecessary IMRT

Use of IMRT for prostate cancer doubles when self-referral's financial incentives involved

Study: Gene Expression Classifier test reduces unnecessary surgeries in thyroid nodule assessment

Diabetic patients may require higher doses of metformin to achieve same anti-cancer activity

Just 13 days in space may cause changes in eye structure, gene expression

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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