Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

American Academy of Otolaryngology publishes new guideline on “Improving Voice Outcomes after Thyroid Surgery”

The American Academy of Otolaryngology-Head and Neck Surgery Foundation on Tuesday published a new Clinical Practice Guideline on "Improving Voice Outcomes after Thyroid Surgery" to recognize the importance of the patient's voice and the potential impact thyroid surgery can have on it.

4 Jun 2013

Altered function of neural circuitry contributes to bulimia and anorexia

Anorexia nervosa and bulimia nervosa -disorders characterized by extreme eating behavior and distorted body image - are among the deadliest of psychiatric disorders, with few proven effective treatments.

4 Jun 2013

NanoString's Prosigna Breast Cancer Assay can help identify node-positive early-stage breast cancer

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and molecular diagnostic products, today announced new results from the combined data analysis of the Austrian Breast & Colorectal Cancer Study Group 8 (ABCSG-8) and Arimidex, Tamoxifen, Alone or in Combination studies.

From NanoString Technologies 3 Jun 2013

Study investigates gene expression signature to predict response to bevacizumab

A new test may help identify newly diagnosed glioblastoma patients more likely to benefit from bevacizumab (Avastin-), according to new research from The University of Texas MD Anderson Cancer Center.

3 Jun 2013

NanoString Technologies to present clinical study of Prosigna Breast Cancer Assay at ASCO 2013

NanoString Technologies, Inc., a privately held provider of life science tools for translational research and molecular diagnostic products, today announced that a clinical study of the Prosigna Breast Cancer Assay will be presented during the Breast Cancer Oral Abstract Session at the 2013 Annual American Society of Clinical Oncology Meeting on Sunday, June 2.

From NanoString Technologies 1 Jun 2013

International researchers find how brain cancer cells survive and drive tumor growth

An international team of researchers - led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine - has found that a singular gene mutation helps brain cancer cells to not just survive, but grow tumors rapidly by altering the splicing of genes that control cellular metabolism.

1 Jun 2013

Using germ-killing soap, ointment reduces presence of MRSA in ICUs, study finds

Using germ-killing soap and ointment on all intensive-care unit patients can reduce bloodstream infections by up to 44 percent and significantly reduce the presence of methicillin-resistant Staphylococcus aureus in ICUs, according study results published in today's New England Journal of Medicine.

31 May 2013

Researchers develop new gene therapy to thwart potential influenza pandemic

Researchers at the Perelman School of Medicine, University of Pennsylvania have developed a new gene therapy to thwart a potential influenza pandemic. Specifically, investigators in the Gene Therapy Program, Department of Pathology and Laboratory Medicine, directed by James M. Wilson, MD, PhD, demonstrated that a single dose of an adeno-associated virus expressing a broadly neutralizing flu antibody into the nasal passages of mice and ferrets gives them complete protection and substantial reductions in flu replication when exposed to lethal strains of H5N1 and H1N1 flu virus.

30 May 2013

Researchers codify age-specific probabilities of live birth after IVF with frozen eggs

Researchers from New York Medical College and the University of California Davis have for the first time codified age-specific probabilities of live birth after in vitro fertilization (IVF) with frozen eggs.

30 May 2013

Medical researchers identify genetic marker associated with sporadic breast cancer

Medical researchers at the University of Alberta have pinpointed a genetic marker for sporadic breast cancer - one of a handful identified to date in Caucasians.

29 May 2013

PathCentral unveils AP Anywhere Express Anatomic Pathology Laboratory Information System

PathCentral, a technology-enabled company dedicated to the success of the pathology community, today unveiled its AP Anywhere Express Anatomic Pathology Laboratory Information System.

28 May 2013

New animal model provides insight into early stages of Parkinson's disease

At the present, no cure exists for Parkinson's disease, although symptomatic intervention, including treatment with dopamine agonists, can alleviate patients' motor impairment. Parkinson's is the second most common neurodegenerative disorder, after Alzheimer's disease; it is estimated that 100,000 to 300,000 patients are affected by Parkinson's disease in Germany alone.

28 May 2013

Researchers identify mutations in new genes that might be associated with ALS disease

Researchers at the Stanford University School of Medicine have identified mutations in several new genes that might be associated with the development of spontaneously occurring cases of the neurodegenerative disease known as amyotrophic lateral sclerosis, or ALS.

27 May 2013

Some aggressive forms of prostate cancer have similar genetic origins

Mayo Clinic researchers have used next generation genomic analysis to determine that some of the more aggressive prostate cancer tumors have similar genetic origins, which may help in predicting cancer progression. The findings appear online today in the journal Cancer Research.

24 May 2013

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Even while being dragged to its destruction inside a cell, a cancer-promoting growth factor receptor fires away, sending signals that thwart the development of tumor-suppressing microRNAs before it's dissolved, researchers reported in an early online publication at Nature.

24 May 2013

Research shows PODXL protein contributes to aggressive forms of bladder cancer

Aggressive forms of bladder cancer involve the protein PODXL - a discovery that could hold the key to improved treatment, according to researchers at Lund University, Uppsala University and KTH in Sweden.

24 May 2013

Common type of childhood asthma is not related to allergens and inflammation

Little is known about why asthma develops, how it constricts the airway or why response to treatments varies between patients. Now, a team of researchers at Weill Cornell Medical College, Columbia University Medical Center and SUNY Downstate Medical Center has revealed the roots of a common type of childhood asthma, showing that it is very different from other asthma cases.

24 May 2013

Pathology News and Research

Further Reading

American Academy of Otolaryngology publishes new guideline on “Improving Voice Outcomes after Thyroid Surgery”

Altered function of neural circuitry contributes to bulimia and anorexia

NanoString's Prosigna Breast Cancer Assay can help identify node-positive early-stage breast cancer

Study investigates gene expression signature to predict response to bevacizumab

NanoString Technologies to present clinical study of Prosigna Breast Cancer Assay at ASCO 2013

International researchers find how brain cancer cells survive and drive tumor growth

Using germ-killing soap, ointment reduces presence of MRSA in ICUs, study finds

Researchers develop new gene therapy to thwart potential influenza pandemic

Researchers codify age-specific probabilities of live birth after IVF with frozen eggs

Medical researchers identify genetic marker associated with sporadic breast cancer

PathCentral unveils AP Anywhere Express Anatomic Pathology Laboratory Information System

New animal model provides insight into early stages of Parkinson's disease

Researchers identify mutations in new genes that might be associated with ALS disease

Some aggressive forms of prostate cancer have similar genetic origins

EGFR gums up cell's miRNA-processing machinery under oxygen starvation conditions

Research shows PODXL protein contributes to aggressive forms of bladder cancer

Common type of childhood asthma is not related to allergens and inflammation

Drug addiction can be visualized in specific regions of brain that determine decision-making

Researchers reveal roots of a common type of childhood asthma

Mayo Clinic, Cancer Genetics form joint venture to improve cancer care

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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