Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Single nucleotide polymorphisms and forensic genetics, maybe not such a perfect combination

Forensic genetics is the branch of genetics that, through DNA analysis and comparison, deals with the resolution of legal problems such as paternity tests.

21 Oct 2004

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Researchers at Virginia Commonwealth University’s Massey Cancer Center received a prestigious award and a $600,000 grant from the V Foundation for Cancer Research, one of the nation’s leading organizations devoted exclusively to funding cancer research.

20 Oct 2004

Scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia

UCLA scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia, (A-T), a life-shortening disorder that devastates the neurological and immune systems of one in 40,000 young children.

19 Oct 2004

Significant steps to fight a deadly childhood muscle cancer

University of Utah scientists have taken significant steps to fight a deadly childhood muscle cancer by identifying some of the genetic events that cause the disease and then engineering mice that develop the tumors.

16 Oct 2004

University of Cambridge executes exclusive patent licences and collaborative research and development agreement with Gene Networks International

The University of Cambridge has entered into two licence agreements with Gene Networks International (GNI), granting exclusive rights to Cambridge's intellectual property related to angiogenesis (the growth of new blood vessels) and inflammation that may have implications in the identification of new drug targets for a range of diseases.

13 Oct 2004

New research suggests that cancer cells can be reformed

New research by Dean Felsher, MD, PhD, assistant professor of medicine (oncology) and of pathology at the Stanford University School of Medicine, suggests that cancer cells can be reformed.

12 Oct 2004

Researchers identify common mutation in T-cell acute lymphocytic leukemia

Researchers at Brigham and Women’s Hospital (BWH) and Dana-Farber Cancer Institute (DFCI) have made a breakthrough discovery, identifying a common mutation in T-cell acute lymphocytic leukemia (T-ALL), an important form of cancer in children and adolescents.

11 Oct 2004

Research examines why a person’s mental health is important for maintaining a satisfying marriage

Results from the research show that each spouse’s level of anxiety and depression predicted not only their own marital satisfaction but their spouse’s as well.

11 Oct 2004

Study raises important questions about the use of drugs that promote or prevent angiogenesis

Dartmouth Medical School cardiology researchers have discovered a new mechanism for what drives the growth of muscle tissue in the lining of injured heart vessels that can eventually lead to blockage.

11 Oct 2004

Research has identified Dectin-1 as the beta-glucan receptor on immune cells

This finding may be of use in the prophylactic prevention of a variety of infections, especially in surgical patients, and in the treatment of cancer. The identification of Dectin-1 as the beta-glucan receptor may also provide a novel strategy for combating fungal infections.

10 Oct 2004

$10 million to establish a multidisciplinary research program in cancer nanotechnology

The National Institutes of Health (NIH) has awarded scientists from Emory University and the Georgia Institute of Technology two new collaborative research grants, totaling nearly $10 million, to establish a multidisciplinary research program in cancer nanotechnology and to develop a new class of nanoparticles for molecular and cellular imaging.

6 Oct 2004

Research continues to show the cardiovascular benefits of fish consumption or omega-3 fatty acids

USA-Peer-reviewed research continues to show the cardiovascular benefits of fish consumption or intake of long-chain omega-3 polyunsaturated fatty acids (n-3 LC-PUFAs).

5 Oct 2004

FDA fast tracks Genaera's drug for the treatment of wet age-related macular degeneration

Genaera Corporation has announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to squalamine, an intravenously administered, first in class, small molecule anti-angiogenic drug for the treatment of "wet" age-related macular degeneration (AMD).

4 Oct 2004

Chemotherapy improves survival and reduces the risk of recurrence in women with stage I ovarian cancer

A new study finds chemotherapy improves survival and reduces the risk of recurrence in women with stage I ovarian cancer (cancer that has not spread beyond the ovary). But it remains unclear which patients would most benefit from adjuvant chemotherapy and what the optimal treatment regimen would entail.

27 Sep 2004

New type of regulatory T cell that reduces asthma and airway inflammation

The team's research not only provides a detailed profile of these newfound cells but also sheds light on how such cells are related to other T cells and suggests that there exists a spectrum of regulatory T cells, known as Tregs, to be identified and studied.

26 Sep 2004

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Researchers targeted Nef, a protein responsible for accelerating the development of acquired immunodeficiency syndrome, or AIDS. Nef was targeted with small molecules synthesized by the researchers – molecules that disrupted Nef’s interaction with other proteins.

26 Sep 2004

Pathology News and Research

Further Reading

Single nucleotide polymorphisms and forensic genetics, maybe not such a perfect combination

Genetic predictions may bring “quantum leap” in breast cancer treatment success

Scientists have devised a novel way to repair one of the genetic mutations that causes ataxia-telangiectasia

Significant steps to fight a deadly childhood muscle cancer

University of Cambridge executes exclusive patent licences and collaborative research and development agreement with Gene Networks International

New research suggests that cancer cells can be reformed

Researchers identify common mutation in T-cell acute lymphocytic leukemia

Research examines why a person’s mental health is important for maintaining a satisfying marriage

Study raises important questions about the use of drugs that promote or prevent angiogenesis

Research has identified Dectin-1 as the beta-glucan receptor on immune cells

$10 million to establish a multidisciplinary research program in cancer nanotechnology

Research continues to show the cardiovascular benefits of fish consumption or omega-3 fatty acids

FDA fast tracks Genaera's drug for the treatment of wet age-related macular degeneration

Chemotherapy improves survival and reduces the risk of recurrence in women with stage I ovarian cancer

New type of regulatory T cell that reduces asthma and airway inflammation

Researchers have successfully targeted an HIV protein that has eluded existing therapies

Study presents multiple lines of evidence against the proposed link between SV40 and human mesotheliomas

Zebrafish atlas will help research community to model human disease

Genome researchers to look at 1918 Spanish flu

Microdebrider better than CO2 laser for removal of most pediatric airway lesions

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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