Pathophysiology News and Research

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Study provides new insight into cluster headache chronicity

A prospective study recently published in the journal Cephalalgia, the official journal of the International Headache Society, extends the idea behind cluster headache chronicity.

2 Jan 2020

New technology developed for treatment of children suffering from respiratory diseases

A new technology to unblock and remove secretions from the respiratory tract of children has been developed as part of a collaboration between researchers at Ben-Gurion University of the Negev and its affiliated Soroka University Medical Center, Cincinnati Children's Hospital Medical Center, and the University of Cincinnati.

4 Dec 2019

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Non-alcoholic fatty liver disease is becoming the most common chronic liver disorder in developed countries. Histological analysis of liver tissue is the only widely accepted test for diagnosing and distinguishing different stages of the disease. However, this technique provides only two-dimensional images of the liver tissue in low resolution and overlooks potentially important 3D structural changes.

4 Dec 2019

Cardiac-specific biomarkers may help predict CVD risk factors early

A new review article provides valuable insights into how traditional and emerging cardiac-specific biomarkers and their associated cardiovascular disease (CVD) risk factors may help point to effective preventive interventions in high-risk obese populations starting at an early stage of disease development.

12 Nov 2019

Discovery of causal link between hydrogen sulfide and schizophrenia

Researchers from the RIKEN Center for Brain Science in Japan have found certain chemical markers that are associated with schizophrenia. They worked with lab mice with models of schizophrenia as well as post mortem brain specimens of persons with schizophrenia. The study titled, “Excess hydrogen sulfide and polysulfides production underlies a schizophrenia pathophysiology,” was published in the latest issue of the journal EMBO Molecular Medicine.

28 Oct 2019

MPST enzyme levels in hair could be a good biomarker for schizophrenia

Working with model mice, post-mortem human brains, and people with schizophrenia, researchers at the RIKEN Center for Brain Science in Japan have discovered that a subtype of schizophrenia is related to abnormally high levels hydrogen sulfide in the brain.

28 Oct 2019

IOF Compendium highlights urgent need to maintain mobility in older populations

Presenting many new facts and figures, a 2nd edition of the International Osteoporosis Foundation Compendium of Osteoporosis has been launched to mark World Osteoporosis Day.

22 Oct 2019

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Huntington's disease (HD) is a fatal hereditary disease for which there is no cure. A novel study from Cedars-Sinai Medical Center, Los Angeles, using pluripotent stem cells advances understanding of how the disease develops and may help pave the way for identifying pathways for future treatments.

21 Oct 2019

Being obese may lead to fat accumulation in the lungs

Obesity is a growing health concern among children and adults across the globe. In the 2016 figures from the World Health Organization (WHO), 1.9 billion adults are overweight worldwide, and of these, over 650 million were obese.

17 Oct 2019

Neurofeedback can change guilt-related brain connectivity in patients with Major Depression Disorder

A study published in the journal Neuroimage: Clinical found that patients with Major Depressive Disorder, who had recovered from symptoms, were able to strengthen some of their brain connections whilst thinking about guilt-evoking memories, thereby increasing their self-esteem.

10 Oct 2019

The Ehlers-Danlos Society Center opens at IU Health to advance research and patient care

The Ehlers-Danlos Society is pleased to announce the opening of The Ehlers-Danlos Society Center at IU Health, committed to advancing research, education and patient care for those living with the Ehlers-Danlos syndromes (EDS), hypermobility spectrum disorders (HSD), and associated symptoms and conditions.

8 Oct 2019

Spatial Gene Expression Profiling of Neurological Disorders

In this interview, Cedric Uytingco discusses the key benefits of being able to visualize gene expression patterns in neurological samples.

From 10x Genomics, Inc. 7 Oct 2019

GW researchers to study the underlying pathophysiology of myasthenia gravis

The National Institutes of Health awarded a research team at the George Washington University $7.8 million to establish a rare disease network for myasthenia gravis. The network, which will be part of 25 established NIH Rare Diseases Clinical Research Networks, will include basic and clinical investigators, patient advocacy groups, and biotechnology and pharmaceutical companies working together to enhance therapeutic development for this rare disease.

4 Oct 2019

UTA researchers pursuing groundbreaking treatment for healing cranial injuries

A University of Texas at Arlington team researching a groundbreaking treatment to accelerate the healing of cranial injuries has received significant funding support from the National Institutes of Health.

1 Oct 2019

CDC to fund sickle cell disease surveillance

The Centers for Disease Control and Prevention (CDC) has announced a funding of $1.2 million to different states in order to collect data and information from people suffering from sickle cell disease. The program called the Sickle Cell Data Collection program or SCDC is at present functional in two states - California and Georgia. With the new funds coming in, nine states would be able to collect and send population based information on the health of persons living with sickle cell disease.

27 Sep 2019

New review provides knowledge about sex-related differences in Parkinson's disease

There is growing evidence that Parkinson's disease affects women and men differently. In this insightful review, published in the Journal of Parkinson's Disease, scientists present the most recent knowledge about these sex-related differences and highlight the significance of estrogens, which play an important role in the sex differences in PD.

25 Sep 2019

Pathophysiology News and Research

Study provides new insight into cluster headache chronicity

New technology developed for treatment of children suffering from respiratory diseases

Researchers create 3D liver model for improved diagnosis of non-alcoholic fatty liver disease

Cardiac-specific biomarkers may help predict CVD risk factors early

Discovery of causal link between hydrogen sulfide and schizophrenia

MPST enzyme levels in hair could be a good biomarker for schizophrenia

IOF Compendium highlights urgent need to maintain mobility in older populations

Pluripotent stem cells help advance understanding of how Huntington's disease develops

Being obese may lead to fat accumulation in the lungs

Neurofeedback can change guilt-related brain connectivity in patients with Major Depression Disorder

The Ehlers-Danlos Society Center opens at IU Health to advance research and patient care

Spatial Gene Expression Profiling of Neurological Disorders

GW researchers to study the underlying pathophysiology of myasthenia gravis

UTA researchers pursuing groundbreaking treatment for healing cranial injuries

CDC to fund sickle cell disease surveillance

New review provides knowledge about sex-related differences in Parkinson's disease

A single dose of yellow fever vaccine does not offer long-term immunity to children

Study identifies inhibitor that protects cells from toxic DUX4 effects

Neurobiological pathophysiology of schizophrenia differs based on gender

Study shows link between family history of diabetes and increased bone mineral density

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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