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On-the-spot test aids postsurgical coagulopathy management

Point-of-care thromboelastometric and aggregometric testing helps to reduce exposure to allogenic blood products in patients with coagulopathy after cardiac surgery, a randomized trial shows.

5 Sep 2012

Arsenic induces acute promyelocytic leukemia remission

Elderly patients with acute promyelocytic leukemia have a high rate of response to arsenic trioxide, say researchers who believe the drug should be a first-line treatment in this population.

5 Sep 2012

Predictors of early death after traumatic bleeding uncovered

The strongest predictors of early death after traumatic postinjury bleeding are Glasgow coma score, age, and systolic blood pressure, report researchers.

4 Sep 2012

Childhood coagulation marker levels distinct from adulthood

Levels of key coagulation markers significantly vary with age in children, research reveals, potentially affecting the diagnosis and treatment of pediatric thrombotic and hemorrhagic disease.

29 Aug 2012

Vitamin to the rescue in fight with ‘superbugs’

High doses of vitamin B3 may help fight against so called “superbugs” such as methicillin-resistant Staphylococcus aureus, show study results.

29 Aug 2012

Life-quality concerns for multiple myeloma survivors

Care of patients with multiple myeloma should not end with the achievement of long-term survival, suggests research indicating many experience poor health-related quality of life in the decade after diagnosis.

22 Aug 2012

Rivaroxaban effective in children

Laboratory tests show no significant differences in rivaroxaban efficacy across children aged from 28 days to 16 years, researchers report.

16 Aug 2012

Pediatric imatinib for Philadelphia-chromosome ALL fights relapse

Trial findings confirm the benefits of imatinib therapy in children with Philadelphia-chromosome-positive acute lymphoblastic leukemia.

15 Aug 2012

Tranexamic acid reduces bleeding in off-pump coronary bypass surgery

Patients undergoing off-pump coronary artery bypass grafting who are given a tranexamic acid infusion show a modest reduction in postoperative bleeding and blood transfusion relative to their placebo-treated peers, a clinical trial shows.

15 Aug 2012

Women with chronic PVT should be informed, not discouraged, about pregnancy

Maternal and fetal outcomes are favorable for most pregnancies that reach 20 weeks’ in women with chronic portal vein thrombosis, a study shows.

13 Aug 2012

Immigration influences HIV diagnosis demographics

HIV-positive individuals born outside the USA are a heterogenous population but have significant demographic differences to infected patients born within in the USA, research reveals.

8 Aug 2012

Vorinostat drives HIV from hiding

The addition of vorinostat to current antiretroviral therapy regimens can potentially help to eradicate hidden pockets of dormant human immunodeficiency virus, according to study results published in Nature.

6 Aug 2012

Novel integrase inhibitor dolutegravir shows promise for HIV-1 treatment

The once-daily integrase inhibitor dolutegravir has shown promise in a phase III noninferiority study comparing it with twice-daily raltegravir for treatment of HIV-1, indicate study results presented at the 19th International AIDS Conference in Washington DC, USA.

3 Aug 2012