Penicillin News and Research

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Penicillin (sometimes abbreviated PCN or pen) is a group of antibiotics derived from ''Penicillium'' fungi. Penicillin antibiotics are historically significant because they are the first drugs that were effective against many previously serious diseases such as syphilis and Staphylococcus infections.

Dangerous antibiotic-resistant bacteria found in China's ready-to-eat foods

The study reveals high levels of antibiotic-resistant Staphylococcus aureus (MRSA) in ready-to-eat foods across 25 provinces in China, posing a serious public health risk. The findings emphasize the need for stronger food safety measures, as the MRSA strains identified were resistant to multiple antibiotics and exhibited various virulence factors.

10 Sep 2023

FAU researchers discover novel method to identify therapeutic agents to treat addiction

According to the Substance Abuse and Mental Health Services Administration, approximately 40 million people in the United States had a substance use disorder in 2020.

8 Sep 2023

Broad-spectrum antibiotics linked to higher sepsis risk in neonates

A preprint presents evidence for the hypothesis that neonatal sepsis is linked to prenatal antibiotics.

7 Sep 2023

KFF Health News' 'What The Health?': 3 health policy experts you should know

In this special episode, host Julie Rovner, KFF Health News' chief Washington correspondent, interviews three noted health policy experts.

31 Aug 2023

High-fiber diets may help control the adverse effects of antibiotic treatments on beneficial gut microbiota

The role of diet in controlling the structure and function of the gut via chemical environment modulation.

30 Aug 2023

UCF researcher receives $3.4 million to develop new antibiotic to treat tuberculosis

A College of Medicine researcher is developing a new antibiotic related to penicillin to treat tuberculosis (TB) and related lung infections.

16 Aug 2023

Penn State researchers develop new method for creating cyclopropanes

Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive-;potentially explosive-;ingredients. Now, a team of researchers from Penn State has identified and demonstrated a safe, efficient and practical way to create cyclopropanes on a wide variety of molecules using a previously undescribed chemical process.

4 Aug 2023

Using bacteriophages to treat bladder infections

About one in two women are affected by cystitis during her lifetime, and many suffer from recurrent urinary tract infections.

21 Jul 2023

PALACE study: Direct oral challenge can safely remove penicillin allergy label

Penicillin allergy affects more than 25 million people in the United States (up to 1 in 10 Americans) and has been shown to lead to particularly poor health outcomes in pregnant women and surgical patients. It is also a public health threat, leading to antibiotic resistance and infections in hospitalized patients that can be life threatening.

17 Jul 2023

Pharmacist-led intervention can help suppress multi-drug resistant pathogens

The battle to stop the increase of superbugs in hospitals has been an ongoing struggle for healthcare professionals.

13 Jul 2023

Wait, What’s a PBM?

Pharmacy benefit managers, or PBMs, are intermediary companies that negotiate the price of prescription drugs.

13 Jul 2023

Sickle cell disease: A global call to action

Reducing the burden of Sickle Cell Disease (SCD) requires substantial financial and political commitment to improving data-collection, diagnosis, treatment and training - doing so will positively impact the lives of millions of patients and families worldwide - says a new Commission published in The Lancet Haematology journal.

12 Jul 2023

Combination therapy successfully treats Pasteurella multocida-related invasive infections

Announcing a new article publication for Zoonoses journal. Pasteurella multocida, a Gram-negative, penicillin-sensitive coccobacillus that is frequently a member of the normal respiratory microbiota of different animals, remains a clinically important pathogen with the ability to cause severe disease. Few case reports have involved P. multocida infections without animal bites.

4 Jun 2023

Battle against superbugs: E. coli resistance in UTIs shows slight decline

Research finds that the prevalence of antimicrobial resistance (AMR) of uropathogenic Escherichia coli (UPEC) from outpatient uncomplicated UTIs at KPSC has slightly decreased between 2016 and 2021, both for in-person and virtual settings, although the magnitude of the decrease was mostly small. Resistance to penicillins, fluoroquinolones, and TMP-SMX was common.

30 May 2023

Long-ignored antibiotic could help fight against multi-drug resistant bacteria

"The end of modern medicine as we know it." That's how the then-director general of the World Health Organization characterized the creeping problem of antimicrobial resistance in 2012.

16 May 2023

New guidance recommends the discontinuation of antibiotics after closure of incisions

Antibiotics administered before and during surgery should be discontinued immediately after a patient's incision is closed, according to updated recommendations for preventing surgical site infections.

5 May 2023

World Health Day: Giving Universal Health Coverage a Platform

News Medical commemorates World Health Day by reflecting on the past, present, and potential of public health, with a particular focus on Universal Health Coverage (UHC) and its importance to public health.

6 Apr 2023

Inhibition of cell wall formation arrests staphylococcal cell division

We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics.

23 Mar 2023

Study estimates the associations of global and regional antibiotic use with COVID-19 cases and vaccinations during 2020–2022

Researchers evaluated the association between COVID-19 cases and vaccinations with antibiotic use worldwide during the SARS-CoV-2 pandemic between 2020 and 2022.

9 Feb 2023

Multi-country study examines clinical and community antibiotic use during the pandemic

Globally, during the first two years of the COVID-19 pandemic, antibiotics were prescribed to 75 percent of COVID-19 patients despite bacterial coinfection rates averaging less than 10 percent.

6 Feb 2023