Phenotype News and Research

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Researchers evaluate performance of a large language model in phenotyping postpartum hemorrhage patients

Researchers evaluated the performance of a large language model (LLM) in phenotyping postpartum hemorrhage (PPH) patients using discharge notes.

4 Dec 2023

UCLA studies unravel metabolic pathways in prostate cancer treatment

Two new studies led by researchers from the UCLA Jonsson Comprehensive Cancer Center give insight into how cells use energy to influence the way prostate tumors survive and grow -; advancements that can help explain why some prostate cancers become resistant to hormone therapy, the most commonly used treatment for men with advanced stages of the disease.

4 Dec 2023

Navigating STXBP1-related disorders: Unraveling clinical and developmental outcomes

Researchers examined the combined patient-years of seizure and developmental histories in individuals with disorders related to the STXBP1 gene.

4 Dec 2023

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

Researchers examinea the effects of temporal morphogen gradient during neural induction on the formation of brain organoids.

4 Dec 2023

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Psoriasis etiopathogenesis and treatment.

29 Nov 2023

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Researchers in the U.S. used non-human primate models to explore the molecular mechanisms and neural systems behind behavioral inhibition, a key risk factor for anxiety disorders. The study identified molecular systems in the posterior orbitofrontal cortex linked to variations in anxious temperament, offering potential targets for treating anxiety disorders.

28 Nov 2023

Microneedle bandage offers new hope for diabetic wound treatment

Researchers developed a microneedle (MN) bandage containing selenium (Se) and chlorin e6 (Ce6) hybrid nanoparticles (SeC@PA) for diabetic wound therapy.

28 Nov 2023

SECRE technique paves way for new therapeutics for autoimmune diseases

Scientists have developed a potentially transformative new technique that could aid in the discovery and development of new therapeutics for a number of globally prevalent autoimmune diseases.

27 Nov 2023

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

23 Nov 2023

Isolation measures during pandemic drove faster, more transmissible SARS-CoV-2 variants, study reveals

A Nature Communications study finds that isolation practices during the COVID-19 pandemic influenced the evolution of SARS-CoV-2, leading to variants with earlier, higher peak viral loads but shorter infection durations, suggesting a shift towards increased transmissibility.

23 Nov 2023

Research reveals how isolation measures influence SARS-CoV-2's evolutionary trajectory

Researchers used previously reported empirical clinical data analysis and multi-level mathematical modeling to forecast changes in SARS-CoV-2 dynamics during infection and evolution.

23 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Phenotype News and Research

Researchers evaluate performance of a large language model in phenotyping postpartum hemorrhage patients

UCLA studies unravel metabolic pathways in prostate cancer treatment

Navigating STXBP1-related disorders: Unraveling clinical and developmental outcomes

Temporal morphogen-driven neural induction spurs growth of expanded brain organoids with enhanced neuroepithelium formation

Revolutionary advances in psoriasis treatment: unveiling new therapeutic approaches

Decoding anxiety: Study reveals brain's role in behavioral inhibition risks

Microneedle bandage offers new hope for diabetic wound treatment

SECRE technique paves way for new therapeutics for autoimmune diseases

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Isolation measures during pandemic drove faster, more transmissible SARS-CoV-2 variants, study reveals

Research reveals how isolation measures influence SARS-CoV-2's evolutionary trajectory

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Engineering approach reveals surprising macrophage phenotype with best tumor-targeting ability

New diagnostic workflow improves detection of 5q-spinal muscular atrophy

New lipidic peptide IK14004 shows promise in treating cancer and reducing autoimmune complications

Intestinal MCT1 plays a crucial role in sex-dependent metabolic regulation

Study reveals mechanisms underlying non-suppressible HIV viremia

AI-powered method could revolutionize cancer treatment by interpreting tumor tissue data

Pioneering study finds predictive biomarker in lung adenocarcinoma

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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