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Human physiology is the science of the mechanical, physical, and biochemical functions of humans in good health, their organs, and the cells of which they are composed. The principal level of focus of physiology is at the level of organs and systems. Most aspects of human physiology are closely homologous to corresponding aspects of animal physiology, and animal experimentation has provided much of the foundation of physiological knowledge. Anatomy and physiology are closely related fields of study: anatomy, the study of form, and physiology, the study of function, are intrinsically tied and are studied in tandem as part of a medical curriculum.
Male signals trigger female animals for reproduction but with harmful effects

Male signals trigger female animals for reproduction but with harmful effects

A research team led by a Northwestern University scientist has discovered that male animals, through their invisible chemical "essence," prime female animals for reproduction but with the unfortunate side effect of also hastening females' aging process. [More]
New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

New study raises safety concerns on clinical use of caspase inhibitors for liver diseases

Many acute and chronic liver diseases, including alcoholic hepatitis, result from apoptotic (programmed) cell death mediated by the enzyme caspase. Caspase inhibitors have therapeutic potential to treat and prevent apoptosis-mediated liver injury, and some are currently in clinical trials. [More]
Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

Novel controlled clinical trial finds Ayurvedic-based well-being program can alter blood-based metabolites

In a novel controlled clinical trial, participants in a six-day Ayurvedic-based well-being program that featured a vegetarian diet, meditation, yoga and massages experienced measurable decreases in a set of blood-based metabolites associated with inflammation, cardiovascular disease risk and cholesterol regulation. [More]
Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Penn researchers develop open-source software to infer evolutionary track of tumor metastasis

Individual cells within a tumor are not all the same. This may sound like a modern medical truism, but it wasn't very long ago that oncologists assumed that taking a single biopsy from a patient's tumor would be an accurate reflection of the physiological and genetic make-up of the entire mass. [More]
UAB researchers find microRNA as potential therapeutic target for MDD

UAB researchers find microRNA as potential therapeutic target for MDD

A tiny RNA appears to play a role in producing major depression, the mental disorder that affects as many as 250 million people a year worldwide. [More]
Next-generation advanced translational research preclinical imaging system unveiled by Bruker

Next-generation advanced translational research preclinical imaging system unveiled by Bruker

Bruker today unveils two new preclinical imaging systems at the World Molecular Imaging Congress 2016 in New York. The new systems are designed to deliver highest performance and improved convenience for routine imaging, and enable novel translational research into the causes, progression, as well as potential diagnosis and treatment of disease. [More]
New mouse model helps identify potential drug target for hard-to-treat social aspects of ASD

New mouse model helps identify potential drug target for hard-to-treat social aspects of ASD

A study of a new mouse model identifies a drug target that has the potential to increase social interaction in individuals with some forms of autism spectrum disorder (ASD), according to researchers in the Perelman School of Medicine at the University of Pennsylvania. The team published their work in Biological Psychiatry. [More]
Researchers unlock genetic code that disrupts response to breast cancer therapy

Researchers unlock genetic code that disrupts response to breast cancer therapy

Scientists may have unlocked the genetic code that determines why many patients with estrogen receptor-positive breast cancer fail to respond to the widely used drug tamoxifen. [More]
School-based exercises may benefit bone mass, strength in growing children

School-based exercises may benefit bone mass, strength in growing children

Moderate to high impact sports such as gymnastics, basketball, or football have been shown to benefit bone mass, structure and strength - with benefits particularly apparent during pre-and early adolescence. [More]
Beta-blockers can help treat bone loss caused by antidepressants in mice

Beta-blockers can help treat bone loss caused by antidepressants in mice

The antidepressant fluoxetine causes bone loss by instructing the brain to send out signals that increase bone breakdown, but a beta-blocker can intercept the signals, a new study in mice has found. [More]
Heart specialists to examine benefit of ECG screening for student athletes

Heart specialists to examine benefit of ECG screening for student athletes

UT Southwestern Medical Center heart specialists will study whether electrocardiograms (ECGs) are useful in identifying Texas high school student athletes who are at risk of suffering sudden cardiac death. [More]
Researchers identify potential new way of treating hypertension

Researchers identify potential new way of treating hypertension

Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years. [More]
Enzyme from oral bacteria could be potential therapy for celiac disease

Enzyme from oral bacteria could be potential therapy for celiac disease

Researchers have isolated an enzyme from bacteria present in human saliva that has potential as a therapy for celiac disease (CD), an autoimmune disorder that causes severe digestive and other health problems among sufferers when they consume gluten. [More]
Learning foreign languages can enhance the brain's ability to code information

Learning foreign languages can enhance the brain's ability to code information

Scientists from the Higher School of Economics together with colleagues from the University of Helsinki have discovered that learning foreign languages enhances the our brain's elasticity and its ability to code information. [More]
Moderation and appropriate rest periods may be key to healthier CrossFit workouts

Moderation and appropriate rest periods may be key to healthier CrossFit workouts

Are you a fitness enthusiast? If so, moderation and appropriate rest periods may be the key to healthier exercise, as consecutive CrossFit-style workouts could impair the immune system by affecting inflammatory proteins. [More]
Study shows impaired sexual health and function common after heart attacks

Study shows impaired sexual health and function common after heart attacks

New research from the University of Chicago investigates what happens to men's and women's sexual function and relationships after a heart attack in an effort to help clinicians develop better care guidelines for patients. [More]
New research sheds light on underlying genetic basis of heart arrhythmias

New research sheds light on underlying genetic basis of heart arrhythmias

In the August 31 issue of Science Translational Medicine, new research from the University of Chicago shows how deficits in a specific pathway of genes can lead to the development of atrial fibrillation, a common irregular heartbeat, which poses a significant health risk. [More]
Common signaling pathway may control formation of tumor cells in fat, reveals Purdue study

Common signaling pathway may control formation of tumor cells in fat, reveals Purdue study

A common cell signaling pathway that controls differentiation of stem cells may also control the formation of tumor cells in fat, according to a Purdue University study. [More]
Mitosis study identifies new potential target for cancer therapy

Mitosis study identifies new potential target for cancer therapy

Structural biologists show in a new study that an apparently key step in the process of cell division depends on a unique interaction among specific proteins, including one that is strongly linked to cancer. Their hope now is that the detailed new characterization of the interaction will make it a target for exploring a new cancer therapy. [More]
Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

Study reveals vital new details about inner workings of CRISPR-Cas9 machinery in live cells

A study in The Journal of Cell Biology by scientists at the University of Massachusetts Medical School reveals important new details about the inner workings of the CRISPR-Cas9 machinery in live cells that may have implications for the development of therapeutics that use the powerful gene editing tool. [More]
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