Polymerase News and Research

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Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

Researchers developed an RNA-based switch, the pA regulator system, to control gene expression in mammalian cells by modulating synthetic polyA signal cleavage, offering a novel approach for gene therapy applications.

4 Jan 2024

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Study explores the potential of EZH2 inhibitors GSK126 and Tazemetostat in stimulating β-cell regeneration from pancreatic ductal progenitor cells, offering a novel therapeutic approach for Type 1 Diabetes.

3 Jan 2024

Spicing up the fight: Saffron's powerful impact on prostate cancer revealed

Saffron-treated prostate cancer (PCa) cells.

3 Jan 2024

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

Study evaluates the impact of hybrid immunity on SARS-CoV-2 antibody levels in Canadian adults, revealing that hybrid immunity, combining vaccination and recovery from infection, significantly reduces COVID-19 morbidity and mortality.

2 Jan 2024

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

Study demonstrates that the BNT162b2 SARS-CoV-2 XBB1.5 variant-modified vaccine significantly reduces the risk of COVID-19-related hospitalizations and ambulatory visits, outperforming previous vaccine versions in the face of evolving virus strains.

2 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

Early embryo DNA replication program reveals unexpected flexibility

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next.

20 Dec 2023

New Year's Eve celebrations linked to spike in COVID-19 cases: Small gatherings, not large events, the main culprit

Study investigates the impact of New Year's Eve celebrations on SARS-CoV-2 transmission in Belgium, revealing that small-scale social gatherings, rather than large events, significantly contributed to a surge in COVID-19 cases among higher education students.

18 Dec 2023

HPV infections increase prostate cancer risk by 2.3 times, study finds

Study investigates the association between HPV infections and prostate cancer, revealing that HPV patients have a 2.3-fold increased risk of developing prostate cancer compared to those without HPV.

18 Dec 2023

Transgenic carrots producing nisin protein show promise as natural food preservatives

Study explores the production of nisin protein in transgenic carrots, demonstrating its potential as a natural preservative effective against bacterial pathogens in food and juices.

18 Dec 2023

Intranasal COVID-19 vaccine shows promise in reducing severe symptoms

Study evaluates the single-dose intranasal spray vaccine dNS1-RBD, finding it effective against symptomatic COVID-19, particularly in reducing severe symptoms and respiratory issues.

15 Dec 2023

Gene therapy shows promise for arrhythmogenic cardiomyopathy

Researchers evaluated the effectiveness of adeno-associated virus (AAV)-mediated Plakophilin 2 (PKP2) delivery in treating arrhythmogenic cardiomyopathy (ACM).

12 Dec 2023

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

Researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into mRNAs affects ribosomal frameshifting and the overall fidelity of mRNA translation.

7 Dec 2023

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Researchers created Drosophila models using multi-omics profiles to elucidate the biological mechanisms and effects of everyday low-intensity blue light exposure (BLE).

7 Dec 2023

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

The clinical significance of Streptococcus agalactiae (Group B Streptococcus; GBS) deoxyribonucleic acid (DNA) in the placenta.

4 Dec 2023

New 4-in-1 test can differentiate between swine flu, COVID-19, RSV, and influenza

The first case of a new strain of ‘swine flu’ has been detected in a human in the UK. The last swine flu pandemic killed 457 people in Britain alone. A leading testing expert says this strain looks to be very different but is urging Brits to take precautions.

4 Dec 2023

Polymerase News and Research

Revolutionary RNA-based switch offers new control over gene expression in mammalian cells

EZH2 inhibitors show promise in regenerating insulin-producing cells for type 1 diabetes treatment

Spicing up the fight: Saffron's powerful impact on prostate cancer revealed

Hybrid immunity's role in curbing COVID-19: Canadian study sheds light on vaccine-infection synergy

New Pfizer/BioNTech vaccine variant shows enhanced protection against COVID-19 hospitalization

How immune cells shape our earliest breaths

Early embryo DNA replication program reveals unexpected flexibility

New Year's Eve celebrations linked to spike in COVID-19 cases: Small gatherings, not large events, the main culprit

HPV infections increase prostate cancer risk by 2.3 times, study finds

Transgenic carrots producing nisin protein show promise as natural food preservatives

Intranasal COVID-19 vaccine shows promise in reducing severe symptoms

Gene therapy shows promise for arrhythmogenic cardiomyopathy

A step forward in vaccine technology: Exploring the effects of N1-methylpseudouridine in mRNA translation

From LED screens to genes: The effects of blue light on aging and m6A methylation in fruit flies

Study links placental Group B Streptococcus to higher neonatal unit admissions in newborns

New 4-in-1 test can differentiate between swine flu, COVID-19, RSV, and influenza

Poverty and poor housing linked to increased risk of mobility issues after COVID-19

Alarming rise in antibiotic-resistant urogenital infections in Greece, study shows escalating resistance trends

Breakthrough in Malaria detection: new FREM platform delivers 98% accuracy for rapid screening and genotyping

New study provides convincing evidence of the essential role of cylicins in sperm development and fertility

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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