Progesterone News and Research

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Zometa reduces bone loss in patients receiving breast cancer treatment

Data presented at the American Society of Clinical Oncology (ASCO) annual meeting in Orlando, Florida, demonstrate that Zometa (zoledronic acid), an intravenous bisphosphonate, was shown to inhibit bone loss in postmenopausal women treated with Femara (letrozole) in the adjuvant breast cancer setting (directly following surgery to prevent cancer recurrence).

16 May 2005

Postmenopausal women who consume even moderate amounts of alcohol may face an increased risk of breast cancer

Postmenopausal women who consume even moderate amounts of alcohol may face an increased risk of breast cancer, particularly if their cancer is fueled by the hormones estrogen or progesterone, according to a data analysis by researchers at Boston's Dana-Farber Cancer Institute, Brigham and Women's Hospital, and Harvard School of Public Health.

15 May 2005

Simple and efficient method for creation of novel protein functions in an existing protein scaffold

By designing a molecular bridge, scientists at the University of Illinois at Urbana-Champaign have forged a successful pathway through a complex ocean of barriers: They've changed the function of a protein using a co-evolution approach.

8 May 2005

HIV treatment not affected by hormonal birth control

Estrogen and progesterone hormones in birth control do not influence the effectiveness of highly active antiretroviral therapy (HAART), which is used to treat HIV infection, according to researchers from the Johns Hopkins Bloomberg School of Public Health and other institutions. The study is published in the May 1, 2005, issue of the American Journal of Epidemiology.

2 May 2005

HRT now linked to cancer of the womb

A new study of more than 700,000 women has found, say the researchers, that Hormone replacement therapy (HRT) can increase the risk of cancer of the womb, depending on the form of HRT used.

1 May 2005

Risk of womb cancer now linked to some hormone-replacement therapy

Researchers in the UK say that certain types of hormone-replacement therapy (HRT) increase a woman’s risk of womb cancer while others do not. The study found that though many post-menopausal women, who have not had a hysterectomy, use combined HRT because oestrogen only are thought to increase the risk of womb cancer, little information exists on the incidence of womb cancer in users of these other therapies.

1 May 2005

Baby hormone reduces risk of breast cancer

It has been common knowledge that having a baby by the age of 20 cuts a woman's future risk of breast cancer in half, but now U.S. scientists at the Fox Chase Cancer Centre, Philadelphia, have shown that the hormone that heralds pregnancy could offer a way to prevent breast cancer.

19 Apr 2005

The facts on prenatal care

The nine months of pregnancy come complete with a rich folklore, from guessing at a baby’s sex by the expectant mother’s shape to home remedies for morning sickness. Along with these ageless stories and advice, women also face a variety of recommendations from the modern world of medicine on how best to take care of themselves during pregnancy.

3 Apr 2005

Female sex hormones have a profound effect on susceptibility to the herpes simplex virus

Two McMaster University studies, to be published in the Journal of Virology, show that sex hormones have a profound effect on susceptibility of female mice to the herpes simplex virus, type 2 (HSV-2 ), one of the most common sexually transmitted diseases.

21 Feb 2005

Why estrogenic hormones produce unintended results in women

New research is shedding light on why estrogenic hormones produce unintended results in women, giving hope to the idea that new drugs might reach their targets and work more effectively. Ultimately it could mean that postmenopausal women would know that hormone-replacement therapy would have only its intended result.

13 Feb 2005

Sex hormone progesterone metabolite allopregnanolone reduces stress

A steroid hormone released during the metabolism of progesterone, the female sex hormone, reduces the brain's response to stress, according to research in rats by scientists at Emory University School of Medicine, the Yerkes National Primate Research Center and Atlanta's Center for Behavioral Neuroscience.

9 Feb 2005

Nearly 10,000 preterm births could have been prevented in 2002

Nearly 10,000 preterm births could have been prevented in 2002 if all pregnant women at high risk for a premature baby and eligible for weekly injections of a derivative of the hormone progesterone had received them, according to a new study published in the February issue of Obstetrics & Gynecology.

31 Jan 2005

Why some men develop aggressive prostate cancer that becomes resistant to hormone-withdrawal therapy

Researchers found that certain mutations in a protein called the androgen receptor cause advanced and invasive prostate cancer when put into otherwise healthy mice. The androgen receptor's normal function is to control growth of the prostate gland in response to cues from male hormones called androgens, which have long been thought to stimulate prostate tumors.

26 Jan 2005

Direct modulation of progesterone signaling appears to influence ovarian cancer risk

A woman's risk of ovarian cancer rises significantly if she carries either of two previously unexamined variations in the gene that codes for the progesterone receptor, according to a team of researchers led by scientists from the Keck School of Medicine of the University of Southern California.

5 Jan 2005

Link between body-mass index and oral-contraceptive failure

Overweight and obese women who take oral contraceptives are 60 percent to 70 percent more likely to get pregnant while on the birth-control pill, respectively, than women of lower weight, according to new findings from Fred Hutchinson Cancer Research Center that will be published in the January issue of Obstetrics & Gynecology.

30 Dec 2004

Testosterone has both a physiological and a psychological impact on women’s sexuality

A recently published dissertation from the Karolinska Institutet in Sweden shows that testosterone has both a physiological and a psychological impact on women’s sexuality.

23 Nov 2004

Reproductive hormones have effects on all of these stages of brain growth and development

Scientists are now uncovering increasing evidence that the brain not only responds to hormones produced by the reproductive system, but that these hormones-the so-called "female hormones," estrogen and progestin, and the "male" androgens, such as testosterone-play an important role in the development of differences between male and female brains.

2 Nov 2004

New insights into hormone therapy show when estrogen best aids brain

New hormone therapy studies demonstrate estrogen's ability to directly stimulate neurons, repair damaged neurons, and stimulate support cells—most of which can alleviate some of the cognitive decline associated with menopause.

28 Oct 2004

Progestin in hormone therapy could dramatically affect heart attack severity

“One type of hormone therapy limited heart muscle damage to only 5 percent while another resulted in permanent damage to 35 percent of muscle,” said J. Koudy Williams, Ph.D., lead investigator, from Wake Forest Baptist. “If we can learn more about this mechanism we might be able to identify better hormone therapies for postmenopausal women.”

10 Oct 2004

Contrary to popular belief, women do not suddenly start to lose their memory when menopause begins

Contrary to popular belief, women do not suddenly start to lose their memory when menopause begins, according to a study presented October 4, 2004, at the 129th annual meeting of the American Neurological Association in Toronto.

4 Oct 2004