Promoter News and Research

RSS

Newly discovered molecule plays central role in appetite control mechanisms

A newly discovered molecule increases appetite during fasting -- and decreases it during gorging. The neuron-exciting protein, named NPGL - apparently aims to maintain body mass at a constant, come feast or famine. An evolutionary masterstroke, but not great news for those looking to trim down -- or beef up for the summer.

28 Apr 2017

Epigenetic changes detectable at birth linked to risk of obesity

These changes, known as epigenetic modifications, control the activity of our genes without changing the actual DNA sequence. One of the main epigenetic modifications is DNA methylation, which plays a key role in embryonic development and the formation of different cell types, regulating when and where genes are switched on.

26 Apr 2017

Scientists develop novel technique to screen non-coding DNA of genome for diseases

Researchers have developed a method to swiftly screen the non-coding DNA of the human genome for links to diseases that are driven by changes in gene regulation.

4 Apr 2017

Researchers pinpoint Jumonji protein as key to Ewing's Sarcoma spread

By the time Ewing's Sarcoma is diagnosed, primarily in teens and young adults, it has often spread from its primary site to other parts of the body, making it difficult to treat.

24 Mar 2017

Lack of methyl groups in gene body may lead to emergence of cancer

Every cell in our body contains the complete DNA library. So-called methyl groups regulate that in body tissues only the genetic information is expressed that is indeed needed in this tissue.

23 Feb 2017

Researchers show how metabolism drives proliferation of tumor cells

The metabolic state of tumor cells contributes to signals that control the proliferation of tumor cells. Already the German biochemist and Nobel Prize laureate Otto H. Warburg observed in the 1920s that tumor cells radically change their metabolism.

20 Feb 2017

Sleep may be regulated by several brain-based immune proteins, study reveals

Sleep -- one of the most basic, yet most mystifying processes of the human body -- has confounded physicians, scientists and evolutionary biologists for centuries.

2 Feb 2017

Non-invasive technique for examining fatty tissues could revolutionize medicinal drug testing

That's the hope of Associate Professor Noriyuki Yanaka and researchers at Hiroshima University who have developed a non-invasive way to assess the anti-inflammatory properties of fortified health foods and medications.

31 Jan 2017

JAX researchers unravel mechanism that enables cancer cells to survive and divide

Some cancer cells have a trick up their sleeve to avoid cell death: boosting maintenance of telomeres, the protective "end caps" on chromosomes, and a research team led by Jackson Laboratory Professor Roel Verhaak reports in Nature Genetics on a newly discovered telomere maintenance mechanism.

31 Jan 2017

Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer.

19 Jan 2017

Real-time study of medaka fish aboard ISS sheds light on bone metabolism under microgravity

Tokyo Institute of Technology research: Gravitational biology: Real time imaging and transcriptome analysis of medaka aboard space station

11 Jan 2017

DaVita releases recap of 2016 accomplishments

DaVita Inc., a leading independent medical group and a leading provider of kidney care services in the United States, today released a recap of major accomplishments for the company in 2016, marking its 16th year bringing quality of life to patients and teammates around the world.

30 Dec 2016

Researchers explore how neuronal activity influences CREB dynamics

Neuronal activity mediates the formation of neuronal circuits in the cerebral cortex. These processes are regulated by the transcription factor CREB, which regulates gene expression in neuronal activity-dependent processes.

27 Dec 2016

PITX2 methylation biomarker shows promise for predicting prostate cancer recurrence risk

Prostate-specific antigen (PSA) and other biomarkers are essential tools for diagnosing and monitoring prostate cancer.

8 Dec 2016

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers of the Sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, have first described the methylation profile of Ewing's sarcoma, a cancer of bone and soft tissues that mainly affects children and teenagers.

1 Dec 2016

Penn researchers use CRISPR/Cas9 gene targeting approach to treat hemophilia B in mice

CRISPR/Cas9, a powerful genome editing tool, is showing promise for efficient correction of disease-causing mutations.

1 Dec 2016

Scientists develop safe, highly efficient method to improve searching of new germicides

Scientists from the Lomonosov Moscow State University in cooperation with colleagues have worked out a safe, not that expensive and highly efficient method, which allows to speed up and improve searching of new germicides.

29 Nov 2016

Bone gene in mammals may take additional role to promote cognition in humans

A gene that regulates bone growth and muscle metabolism in mammals may take on an additional role as a promoter of brain maturation, cognition and learning in human and nonhuman prim ates, according to a new study led by neurobiologists at Harvard Medical School.

9 Nov 2016

Study identifies prognostic value of IDH and CIC mutations for grade II/III glioma patients

NRG Oncology investigators have identified two biomarkers that are prognostic of overall and progression-free survival for patients with lower-grade gliomas.

4 Oct 2016

AAFP awards highest honor to North Carolina physician Karen L. Smith

The American Academy of Family Physicians today awarded its highest honor to Karen L. Smith, MD, FAAFP, of Raeford, North Carolina.

25 Sep 2016