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Botox injections may improve frequency of chronic daily and migraine headaches

Although botulinum toxin A injections are U.S. Food and Drug Administration approved for preventive treatment for chronic migraines, a review and analysis of previous studies finds a small to modest benefit for patients with chronic migraine headaches and chronic daily headaches, although botox injections were not associated with greater benefit than placebo for preventing episodic migraine or chronic tension-type headaches, according to an article in the April 25 issue of JAMA.

24 Apr 2012

Orthopaedic research studies in the Journal of Bone and Joint Surgery

Below are highlights of orthopaedic research studies appearing in the April 18th issue of the Journal of Bone and Joint Surgery (JBJS), as well as the issue's full Table of Contents.

21 Apr 2012

Research roundup: Caring for dual eligibles; Antitrust policy and the health law

Using data from the Centers for Disease Control and Prevention (CDC), this report notes a systematic difference in life expectancy across region and race. "Within in each sex-race group, there are striking geographical differences in the probability of survival to age 70. ... These differences are larger for males than females within each race and larger for blacks than whites within each sex."

21 Apr 2012

Study finds under-treatment of RHD in India, Africa

Rheumatic heart disease (RHD) is significantly under-treated in Africa and India according to the preliminary findings of a new global study presented today at the World Congress of Cardiology.

21 Apr 2012

WHO releases guidance on couples testing, counseling, including ART for discordant couples

The WHO on Wednesday released its new 54-page "Guidance on couples HIV testing and counselling, including antiretroviral therapy (ART) for treatment and prevention in serodiscordant couples: Recommendations for a public health approach," according to the Center for Global Health Policy's "Science Speaks" blog.

20 Apr 2012

Researchers, advocates meet in Sydney to discuss state of microbicide, HIV prevention research

"Three decades after the full onset of the global HIV tragedy, science appears to finally be developing preventative measures, including microbicides that would thwart infections in the first place, according to individuals at" the biennial International Microbicides Conference in Sydney, the Asia Sentinel writes.

19 Apr 2012

Anti-HIV pill could prevent thousands of new infections: Study finds

A once daily pill to prevent HIV infection could significantly reduce the spread of the AIDS-causing virus. However it would only be cost-effective if limited to men at very high risk for HIV infection, according to a new study.

18 Apr 2012

No added HIV risk with hormonal contraceptives

An HIV prevention trial that pre-dates the shift to antiretroviral (ARV)-based approaches is nonetheless helping to answer some of the most relevant and topical questions the field is facing today.

18 Apr 2012

International Microbicides Conference to discuss state of HIV prevention research

Researchers, activists and funders are meeting this week in Sydney to discuss the state of HIV prevention research. The biennial International Microbicides Conference, which was opened on Sunday evening by the Honorable Tanya Plibersek MP, Australian Minster of Health, is taking place amid renewed optimism about development and delivery of new HIV prevention options with the potential for ending the AIDS epidemic, including anti-retroviral based microbicides and pre-exposure prophylaxis.

17 Apr 2012

Discontinuing antibiotic used to prevent opportunistic infections among HIV patients could increase risk of malaria, diarrhea

"Abruptly discontinuing co-trimoxazole -- an antibiotic used to prevent opportunistic infections in HIV-positive people -- can lead to a higher incidence of malaria and diarrhea compared with patients who keep on taking the drug," according to a study conducted by the CDC in eastern Uganda and published by the Oxford Journal of Clinical Infectious Diseases in March, PlusNews reports.

12 Apr 2012

Ventria completes VEN100 phase 2 trial on antibiotic-associated diarrhea

Ventria Bioscience has announced the successful completion of a phase 2 clinical trial of its lead therapeutic candidate, VEN100. The study was conducted by a team of investigators from the Department of Epidemiology, Division of Infectious Diseases, and Division of Geriatric Medicine at Johns Hopkins University.

5 Apr 2012

Positive outcome from AiCuris’ Letermovir phase 2b trial on HCMV infections

AiCuris announced today that data on the positive outcome of Letermovir (AIC246) tested in a phase 2b trial in transplant patients will be disclosed at several international meetings on behalf of the AIC246 study team.

3 Apr 2012

CSL Behring initiates rVIIa-FP Phase I study in hemophilia A and B

CSL Behring announced today the first in human dosing of recombinant fusion protein linking coagulation factor VIIa with albumin (rVIIa-FP). The Phase I study will investigate in healthy volunteers the safety and pharmacokinetics of rVIIa-FP in comparison to placebo.

31 Mar 2012

Ethiopia's workplace HIV/AIDS policy aims to help employers, employees nationwide

Ethiopia's new HIV/AIDS workplace policy, instituted in January by the government in cooperation with the country's main employees' and employers' associations, "is expected to protect job seekers from mandatory HIV tests, while facilitating voluntary counseling and testing and defending the right of employees living with HIV to medical leave or job re-allocation," PlusNews reports.

29 Mar 2012

Vaccination for HPV reduces risk of renewed disease

The vaccination against human papillomavirus (HPV) reduces the risk of a renewed HPV-associated illness in patients who have already had diseases as a consequence of an HPV infection.

29 Mar 2012

AHF calls on FDA Commissioner Hamburg to step down

AIDS Healthcare Foundation (AHF), the nation's largest HIV/AIDS organization, today called on Food and Drug Administration (FDA) Commissioner Margaret Hamburg to step down in response to the agency's gross mismanagement of new product reviews and a lack of transparency.

29 Mar 2012

Experts discuss significant findings from CROI in video interview

This post in the AIDS.gov blog provides video of Ron Valdiserri, deputy assistant secretary of health for infectious diseases, interviewing Jonathan Mermin, director of the CDC Division of HIV/AIDS Prevention, at the recent 19th Conference on Retroviruses and Opportunistic Infections.

22 Mar 2012

Westmead Hospital endorse a new medical device designed to increase blood circulation and prevent Deep Vein Thrombosis

A new medical device, the geko™, designed to increase blood circulation through neuromuscular electro–stimulation to the common peroneal nerve, has received the positive endorsement of Westmead Hospital, New South Wales, as an important new development in the prevention of Deep Vein Thrombosis (DVT).

18 Mar 2012

Antibody-based therapies successfully protect monkeys from deadly Ebola and Marburg viruses

Army scientists have demonstrated, for the first time, that antibody-based therapies can successfully protect monkeys from the deadly Ebola and Marburg viruses. In addition, the animals were fully protected even when treatment was administered two days post-infection, an accomplishment unmatched by any experimental therapy for these viruses to date.

14 Mar 2012

ICAP releases results from HPTN 064 Women's HIV Seroincidence Study

ICAP at Columbia University's Mailman School of Public Health is part of a network of research organizations that jointly released results, finding that HIV infection rates of black women living in certain parts of the U.S. are higher than previously estimated for black adolescent and women living in the U.S.

12 Mar 2012

Prophylaxis News and Research

Botox injections may improve frequency of chronic daily and migraine headaches

Orthopaedic research studies in the Journal of Bone and Joint Surgery

Research roundup: Caring for dual eligibles; Antitrust policy and the health law

Study finds under-treatment of RHD in India, Africa

WHO releases guidance on couples testing, counseling, including ART for discordant couples

Researchers, advocates meet in Sydney to discuss state of microbicide, HIV prevention research

Anti-HIV pill could prevent thousands of new infections: Study finds

No added HIV risk with hormonal contraceptives

International Microbicides Conference to discuss state of HIV prevention research

Discontinuing antibiotic used to prevent opportunistic infections among HIV patients could increase risk of malaria, diarrhea

Ventria completes VEN100 phase 2 trial on antibiotic-associated diarrhea

Positive outcome from AiCuris’ Letermovir phase 2b trial on HCMV infections

CSL Behring initiates rVIIa-FP Phase I study in hemophilia A and B

Ethiopia's workplace HIV/AIDS policy aims to help employers, employees nationwide

Vaccination for HPV reduces risk of renewed disease

AHF calls on FDA Commissioner Hamburg to step down

Experts discuss significant findings from CROI in video interview

Westmead Hospital endorse a new medical device designed to increase blood circulation and prevent Deep Vein Thrombosis

Antibody-based therapies successfully protect monkeys from deadly Ebola and Marburg viruses

ICAP releases results from HPTN 064 Women's HIV Seroincidence Study

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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