ICAP releases results from HPTN 064 Women's HIV Seroincidence Study

Published on March 12, 2012 at 2:51 AM · No Comments

ICAP at Columbia University's Mailman School of Public Health is part of a network of research organizations that jointly released results, finding that HIV infection rates of black women living in certain parts of the U.S. are higher than previously estimated for black adolescent and women living in the U.S.

The HIV Prevention Trials Network's (HPTN) 064 Women's HIV Seroincidence Study (ISIS) found an HIV incidence of 0.24% in its study cohort of 2,099 women (88% black)-a rate that is five times higher than that estimated for black women overall in the U.S. by the Centers for Disease Control and Prevention (CDC).

Results from HPTN 064 are based on a study design that selected HIV 'hot spots,' i.e. geographic areas of the U.S. with elevated rates of HIV and poverty. Six distinct geographical areas in the northeast and southeast regions of the U.S. were selected-Atlanta, GA, Raleigh-Durham, NC, Washington D.C., Baltimore, MD, Newark, NJ, and New York City -where women, ages 18 to 44, without a prior positive HIV test were eligible for enrollment.

Within ICAP's consortium of clinical research sites, the HPTN 064 study was conducted at three New York City-area sites: ICAP's Harlem Prevention Center, the Bronx-Lebanon Hospital Center, and the New Jersey Medical School Adult Clinical Research Center. Investigators for the study included Drs. Wafaa El-Sadr, ICAP Director; Jessica Justman, ICAP Senior Technical Director; Sharon Mannheimer, Chief of Infectious Diseases at Harlem Hospital Center; Edward Telzak, Chief of Infectious Diseases/Director of AIDS Program at Bronx-Lebanon Hospital Center; and Sally Hodder, Vice Chair, Department of Medicine and Director, HIV/AIDS Program in the Division of Infectious Diseases at UMDNJ.

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