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The proteome is the entire complement of proteins expressed by a genome, cell, tissue or organism. More specifically, it is the expressed proteins at a given time point under defined conditions. The term is a blend of proteins and genome.

Autophagy can help combat Salmonella and other pathogens

Autophagy - the process of recycling cellular material in the body, can help combat Salmonella and other pathogens according to researchers at the School of Life Sciences, University of Warwick who have studied how autophagy can get rid of bacteria, and prevent diseases developing.

27 Mar 2019

UIC scientists identify hidden proteins in bacteria

Scientists at the University of Illinois at Chicago have developed a way to identify the beginning of every gene -- known as a translation start site or a start codon -- in bacterial cell DNA with a single experiment and, through this method, they have shown that an individual gene is capable of coding for more than one protein.

21 Mar 2019

Universal pan-filovirus T-cell vaccine could offer protection against Ebola and Marburg

Vaccines that induce protective T-cell responses could protect against members across the filovirus family, according to a study published February 28 in the open-access journal PLOS Pathogens by Tomáš Hanke of the University of Oxford, Bette Korber of the Los Alamos National Laboratory, and colleagues.

4 Mar 2019

Discovery paves the way for simple blood test to detect early stages of NAFLD

One in four people in Western and Asian societies develop a build-up of fat in the liver as a result of an unhealthy diet. This disease - referred to as non-alcoholic fatty liver disease (NAFLD) - causes no symptoms initially but can develop into end-stage liver cirrhosis with limited treatment options.

1 Mar 2019

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

Cholesterol carried in high-density lipoprotein particles, or HDL cholesterol, has been dubbed the good cholesterol, because people whose HDL levels are high have a lower risk of developing heart disease. That link was first established in 1977 and has been confirmed over and over in epidemiological studies.

15 Feb 2019

When genomic sequencing fails to diagnose a rare disease

Routine sequencing has given unprecedented insight into the genetics of rare diseases, but genomics fails to diagnose up to half of patients who are tested. That's the problem German scientists tackled in a recent study in the journal Molecular & Cellular Proteomics.

11 Feb 2019

Hibernation spurts of hamsters hold clues to better treatments for Alzheimer's disease

Syrian hamsters are golden-haired rodents often kept as house pets. Cold and darkness can cause the animals to hibernate for 3-4 days at a time, interspersed with short periods of activity.

7 Feb 2019

Gero to present latest results of aging studies at Longevity Therapeutics Conference

Gero is a data-driven longevity company developing innovative therapies that will strongly extend the healthy period of life also known as healthspan. Latest results of Gero aging studies will be presented at Longevity Therapeutics Conference in San Francisco, January 29-31, 2019.

25 Jan 2019

Analyzing proteins in blister fluid may classify burn severity more accurately

Severe burns can leave physical and psychological scars, especially in children. When a burn patient enters the clinic, doctors use factors such as the depth and size of the burn, as well as the time required for skin healing--or re-epithelialization--to determine the best course of treatment.

18 Jan 2019

High-performing MS device reaches new level in characterizing protein impurities

In response to current regulatory guidance a Mass Spectrometry-based Host Cell Protein detection approach with faster, more accurate and wider-ranging detection is essential.

10 Jan 2019

Researchers develop new method of analysis to map cellular locations of proteins

Researchers at Karolinska Institutet and SciLifeLab have developed a new method of analysis that maps the location of proteins in the cell. The information has been compiled in a database that is accessible to researchers around the world.

3 Jan 2019

Researchers discover new changes occurring in the brain in early Alzheimer's disease

Researchers at the University of Eastern Finland have discovered new changes occurring in the human brain in the early stages of Alzheimer's disease.

21 Dec 2018

Scientists discover new biomarkers for early detection of cystic fibrosis

Scientists at McMaster University have discovered several new biomarkers from a single drop of blood that could allow earlier and more definitive detection of cystic fibrosis, a genetic disease which strikes both children and adults, causing chronic problems with the digestive system and the lungs.

20 Dec 2018

Proteome News and Research

Autophagy can help combat Salmonella and other pathogens

UIC scientists identify hidden proteins in bacteria

Universal pan-filovirus T-cell vaccine could offer protection against Ebola and Marburg

Discovery paves the way for simple blood test to detect early stages of NAFLD

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

When genomic sequencing fails to diagnose a rare disease

Hibernation spurts of hamsters hold clues to better treatments for Alzheimer's disease

Gero to present latest results of aging studies at Longevity Therapeutics Conference

Analyzing proteins in blister fluid may classify burn severity more accurately

High-performing MS device reaches new level in characterizing protein impurities

Researchers develop new method of analysis to map cellular locations of proteins

Researchers discover new changes occurring in the brain in early Alzheimer's disease

Scientists discover new biomarkers for early detection of cystic fibrosis

Scientists find answers to how cancer spreads

New version of InSyBio Suite launched to revolutionize biomarker discovery

Microglia show distinct responses under inflammatory conditions

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

Integral Molecular wins NIH grant to initiate target discovery program for Alzheimer’s disease

New project aims to deliver fast, effective treatment for autoimmune rheumatic diseases

Researchers obtain understanding of pathomechanisms underlying two age-related eye disorders

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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