Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Study suggests anxiety increases the risk of subsequent cognitive progression in non-dementia elderly

Researchers investigate the effects of anxiety on cognitive degeneration in non-dementia elderly.

14 Jul 2023

U-M researchers develop animal-free method to produce brain organoids

Researchers at University of Michigan developed a method to produce artificially grown miniature brains -; called human brain organoids -; free of animal cells that could greatly improve the way neurodegenerative conditions are studied and, eventually, treated.

13 Jul 2023

New heart cell atlas reveals detailed structure of the human heart

In a new study, published today (12 July) in Nature, researchers have produced the most detailed and comprehensive human Heart Cell Atlas to date, including the specialised tissue of the cardiac conduction system - where the heartbeat originates.

12 Jul 2023

Researchers discover a molecular switch that regulates lipid metabolism in cells

Our body's fat metabolism plays a vital role in energy production in our body. A research team at the University of Basel, Switzerland, has discovered a molecular switch that regulates lipid metabolism in our cells.

3 Jul 2023

Cutting-edge research: machine learning identifies early predictors of type 1 diabetes

Scientists utilized plasma protein proteomics to identify proteins associated with the onset of type 1 diabetes.

3 Jul 2023

Combining proteomic and miRNA data yields superior age predictions, study suggests

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 12, entitled, "Age prediction from human blood plasma using proteomic and small RNA data: a comparative analysis."

30 Jun 2023

New method can track the complete activity of proteins in living cells

The genetic plans within our DNA come to functional fruition through proteins, which underlie our bodies' structure and activity.

29 Jun 2023

INTEGRA Biosciences’ pipettes help to advance cancer drug discovery

The Institute for Cancer Research (ICR), part of the University of London, is using VIAFLO electronic pipettes from INTEGRA Biosciences to streamline its preclinical drug screening and translational medicine workflows.

From INTEGRA Biosciences 20 Jun 2023

EPFL researchers achieve near-perfect control of individual molecules for improving sensing precision

Aleksandra Radenovic, head of the Laboratory of Nanoscale Biology in the School of Engineering, has worked for years to improve nanopore technology, which involves passing a molecule like DNA through a tiny pore in a membrane to measure an ionic current.

19 Jun 2023

Researchers create a diagnostic test to identify functional sperm in infertile men

In a recent study, researchers created a diagnostic test to identify functional sperm in infertile men that could change the treatment of male infertility and assisted reproductive technology.

14 Jun 2023

Study unveils potential early detection algorithm for neurodegeneration in rare genetic disorder

Xeroderma pigmentosum (XP) is a rare and devastating genetic disorder characterised by an inability to repair skin damage caused by ultraviolet (UV) light.

11 Jun 2023

Ancient, virus-like protein may contribute to ALS

More than 5,000 people are diagnosed annually with ALS (amyotrophic lateral sclerosis), a fatal, neurodegenerative disease that attacks nerve cells in the brain and spinal cord, gradually robbing people of the ability to speak, move, eat and breathe.

7 Jun 2023

Prenatal COVID boosts protective power of breast milk

The impact of SARS-CoV-2 infection during pregnancy on postpartum human milk-derived extracellular vesicles.

6 Jun 2023

Researchers characterize the expression of cardiac proteins during embryonic heart development

Researchers at the UNC School of Medicine, UNC McAllister Heart Institute, and the UNC Lineberger Comprehensive Cancer Center characterized the expression of thousands of cardiac proteins during eight critical stages of embryonic heart development.

6 Jun 2023

When Spectrometry bridges the gap between Proteomics and Biology

In this new episode of omg OMx, Kate Sumpo talks to Balyn Zaro about her research, experiences, and insights as a biologist in proteomics and spectrometry.

From Bruker Life Sciences Mass Spectrometry 2 Jun 2023

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Researchers in the Netherlands assessed the structure of human circulatory IgM and its relationship with the small CD5L protein.

31 May 2023

Modest reduction in beta-amyloidogenic processing of APP may be a viable strategy to prevent Alzheimer's disease

A new study conducted by researchers at the University of Eastern Finland discovered that the APP A673T genetic variant, which protects against Alzheimer’s disease, alters levels of several proteins and peptides linked to amyloid-beta metabolism in human biofluids and cell culture models, including amyloid beta itself.

26 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023

Mays Cancer Center conducts clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma

The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM).

24 May 2023

Researchers produce a multi-scale map of protein assemblies in the DNA damage response

Writing in the May 22, 2023 issue of Cell Systems, a diverse team of scientists, led by researchers at University of California San Diego School of Medicine, have produced a novel map that depicts the human body's enormously complicated and highly evolved system for addressing and repairing DNA damage -; a cause and consequence of many diseases.

22 May 2023