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Psychiatry is the treatment, study and prevention of mental disorders.

Researcher develops novel IBT to help opioid-dependent Vermonters

Opioid dependence - addiction to heroin and prescription painkillers - has reached epidemic levels across the country, with treatment waitlists also at an all-time high. [More]
Studies shed light on propensity for habit formation in obsessive-compulsive disorder

Studies shed light on propensity for habit formation in obsessive-compulsive disorder

Two new studies published this week in Biological Psychiatry shed light on the propensity for habit formation in obsessive-compulsive disorder (OCD). These studies suggest that a tendency to develop habits, i.e., the compulsive component of the disorder, may be a core feature of the disorder rather than a consequence of irrational beliefs. [More]
Researchers win 2014 Joint Team Science Award to improve care for depression in low-income areas

Researchers win 2014 Joint Team Science Award to improve care for depression in low-income areas

A team of community leaders and researchers from UCLA and RAND has been awarded the 2014 Joint Team Science Award in recognition of a 10-year effort to conduct community engaged, population-based translational science to improve care for depression in low-income areas. [More]

UCLA and RAND researchers receive 2014 Joint Team Science Award

A team of community leaders and researchers from UCLA and RAND has been awarded the 2014 Joint Team Science Award in recognition of a 10-year effort to conduct community engaged, population-based translational science to improve care for depression in low-income areas. [More]

Risk factors for complete, attempted suicide in schizophrenia 'confirmed'

Among individuals with schizophrenia, those earliest in their illness course and those with a history of suicide attempts have the highest suicide-related mortality rates, reveals analysis of the international Ziprasidone Observational Study of Cardiac Outcomes. [More]

High relapse rates in bipolar disorder confirmed

Results from a naturalistic study show that there is a high risk of relapse among bipolar disorder patients, particularly if their medication is changed or stopped. [More]
Intranasal ketamine spray confers rapid antidepressant effect in patients with depressive disorder

Intranasal ketamine spray confers rapid antidepressant effect in patients with depressive disorder

A research team from the Icahn School of Medicine at Mount Sinai published the first controlled evidence showing that an intranasal ketamine spray conferred an unusually rapid antidepressant effect -within 24 hours-and was well tolerated in patients with treatment-resistant major depressive disorder. [More]
UCSF launches Brain Health Registry to advance neuroscience research

UCSF launches Brain Health Registry to advance neuroscience research

A new online project led by researchers at UC San Francisco promises to dramatically cut the time and cost of conducting clinical trials for brain diseases, while also helping scientists analyze and track the brain functions of thousands of volunteers over time. [More]

Findings confirm importance of brain activity during sleep for memory strength and accuracy

The sense of smell might seem intuitive, almost something you take for granted. But researchers from NYU Langone Medical Center have found that memory of specific odors depends on the ability of the brain to learn, process and recall accurately and effectively during slow-wave sleep — a deep sleep characterized by slow brain waves. [More]
DNA modifications in blood are directly related to changes in brain tissues, say researchers

DNA modifications in blood are directly related to changes in brain tissues, say researchers

Johns Hopkins researchers say they have confirmed suspicions that DNA modifications found in the blood of mice exposed to high levels of stress hormone — and showing signs of anxiety — are directly related to changes found in their brain tissues. [More]
Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Alkermes announces results from phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia

Alkermes plc today announced positive topline results from a randomized, double-blind, placebo-controlled phase 3 clinical trial of aripiprazole lauroxil in patients with schizophrenia. Patients treated once monthly with either 441 mg or 882 mg of aripiprazole lauroxil demonstrated statistically significant reductions from baseline in Positive and Negative Syndrome Scale (PANSS) total scores at week 12, compared to placebo (p<0.001 aripiprazole lauroxil 441 mg, p<0.001 aripiprazole lauroxil 882 mg), which was the prespecified primary endpoint in the study. Based on the positive results from this phase 3 study, Alkermes plans to submit a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) in the third quarter of 2014. [More]
Exposure to arsenic in drinking water negatively associated with child intelligence, shows study

Exposure to arsenic in drinking water negatively associated with child intelligence, shows study

A study by researchers at Columbia University reports that schoolchildren from three school districts in Maine exposed to arsenic in drinking water experienced declines in child intelligence. [More]
Researchers integrate meditation and science to develop targeted mental health treatments

Researchers integrate meditation and science to develop targeted mental health treatments

Mindfulness is always personal and often spiritual, but the meditation experience does not have to be subjective. Advances in methodology are allowing researchers to integrate mindfulness experiences with brain imaging and neural signal data to form testable hypotheses about the science - and the reported mental health benefits - of the practice. [More]
Study reveals role of dopamine in hippocampus region of brain

Study reveals role of dopamine in hippocampus region of brain

Bruno Giros, PhD, a researcher at the Douglas Mental Health University Institute and a professor in the Department of Psychiatry at McGill University, has demonstrated, for the first time, the role that dopamine plays in a region of the brain called the hippocampus. [More]

Cognitive dysfunction reflected in schizophrenia healthcare costs

Cognitive dysfunction has direct and indirect effects on healthcare costs in patients with schizophrenia, research suggests. [More]

Neurovance closes $6.3M extension to its series A1 financing round to advance development of EB-1020 SR

Neurovance, Inc. today announced that it has closed a $6.3 million extension to its series A1 financing round to further advance development of EB-1020 SR, a non-stimulant, for the treatment of all subtypes of adult ADHD (attention deficit hyperactivity disorder). [More]

FDA clears QbTest for unbiased evaluation of ADHD treatment

The US Food and Drug Administration (FDA) has cleared the neuropsychological test - QbTest - developed by the Swedish company Qbtech to aid in the evaluation of treatment interventions in patients with ADHD. [More]

Study on effect of Botox on depression

In the largest randomized, double-blind, placebo controlled study to date on the effect of OnabotulinumtoxinA (as known as Botox) on depression, researchers found that more than half of subjects suffering from moderate to severe depression showed a substantial improvement (greater than or equal to 50% of baseline) in their depressive symptoms as measured by the MADRS scale. [More]

Study finds that baclofen drug has potential to prevent cocaine relapse

Relapse is the most painful and expensive feature of drug addiction-even after addicted individuals have been drug-free for months or years, the likelihood of sliding back into the habit remains high. The National Institute on Drug Abuse estimates that 40 to 60 percent of addicted individuals will relapse, and in some studies the rates are as high as 80 percent at six months after treatment. [More]
Brain disconnect leaves teen brain less able to judge trustworthiness

Brain disconnect leaves teen brain less able to judge trustworthiness

Making a snap decision usually means following your initial reaction -- going with your gut. That intuitive feeling sprouts from the limbic system, the evolutionarily older and simpler part of the brain that affects emotion, behavior and motivation. [More]