Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Self-harm warns of repeated suicide attempt risk in schizophrenia

Individuals who have attempted suicide and also have a history of self-harm should be thoroughly assessed for psychotic symptoms in order to prevent delayed treatment and the risk for repeated suicide attempts, say researchers.

31 Oct 2013

Large, rare CNV burden reduced in bipolar disorder

Large and rare chromosomal copy number variants are uncommon in patients with bipolar disorder, even those with early-onset disease, study findings confirm.

31 Oct 2013

Mood instability shapes psychotic experiences

Mood instability is a prominent feature of psychosis, say researchers who found it was associated with and predicted the presence of psychotic experiences such as paranoid ideation and auditory hallucinations.

30 Oct 2013

Psychosis prediction model could facilitate early intervention

A integrated model has shown “outstanding” ability to predict the transition to psychosis in clinically high-risk patients, report investigators in Schizophrenia Bulletin.

25 Oct 2013

Research unlocks secrets of mouse behavior to help identify promising psychiatric drugs

Developing psychiatric medications is a long and complex process. Candidate drugs are evaluated and assessed based on their effects on the behavior of animals, usually rats or mice. Each class of drugs, from antidepressants to antipsychotics, is tested differently - often in a labor-intensive process that leaves plenty of room for human error. And there is a growing consensus that current procedures fail to effectively produce new medications.

25 Oct 2013

Autoimmune link to schizophrenia

Patients with schizophrenia have an increased risk for developing autoimmune diseases, especially if they contract an infection, shows a registry-based study.

24 Oct 2013

Multifactorial approach needed for early bipolar detection

At-risk states for bipolar disorder require a multifaceted approach to be identified and appropriately treated, according to preliminary results from the Dresden High-Risk Project.

24 Oct 2013

Schizophrenic hippocampal abnormalities blamed on glutamate

Elevated glutamate levels correlate with reduced tissue volume in the hippocampus of patients with schizophrenia, a study shows.

18 Oct 2013

Psychotic symptoms alone denote medical health risk

People with symptoms of psychosis have an increased rate of medical comorbidities and unhealthy lifestyle habits even if they do not have a psychiatric diagnosis, shows a worldwide study.

17 Oct 2013

Viewpoints: Marketplaces' 'technical foibles' may keep young people from coming back; health law may be ushering in era of narrow networks

The encouraging view is that the overwhelming number of visitors to the site indicates high demand for insurance in the new system. That's critical, because the more people who participate, the better the system works. The danger is that the technical foibles since Oct. 1 will discourage people from coming back, particularly the young and healthy customers the system needs to keep rates reasonable. With some big deadlines approaching, the Obama administration needs to fix the bugs, and fast. People who need insurance from the federal marketplace have until mid-December to buy coverage that begins Jan. 1. If enrollment figures aren't robust by then, the new health-care system will have a problem even bigger than a frustrating Web (10/11).

15 Oct 2013

Kraepelin distinctions back in favor

Modern statistical methods support Kraepelin’s original distinction between schizophrenia and bipolar disorder, but not the more recent schizoaffective disorder category, say researchers.

11 Oct 2013

Antisocial path to violence in psychosis

People are at particular risk for violent behavior during a first episode of psychosis if they have displayed antisocial behavior since childhood, show findings from the UK National EDEN Study.

10 Oct 2013

Self-management toolkit helps relatives of people with new-onset psychosis

Findings from a recent real-world clinical study indicate that relatives of people with recent-onset psychosis benefit from supported self-management interventions to help with outcomes such as distress and negative feelings around caregiving.

9 Oct 2013

UCLA investigates high rates of schizophrenia in people with 22q11.2 deletion syndrome

UCLA has joined an international consortium to investigate the high rates of schizophrenia and other neuropsychiatric disorders in those who are affected with Chromosome 22q11.2 deletion syndrome, a disorder caused by the deletion of a small piece of chromosome number 22.

9 Oct 2013

Parkinsonism predicts schizophrenia cognitive course

Parkinsonism is common in patients with first-episode psychosis and is predictive of cognitive impairment, say researchers.

3 Oct 2013

Affective dimensions aid bipolar disorder diagnosis

Measuring affective dimensions can help clinicians diagnose bipolar disorder in patients with first-episode psychosis, researchers report.

3 Oct 2013

Adolescent psychotic experiences lack uniformity

Psychotic experiences in adolescence appear to be quite distinct and vary widely from individual to individual, study findings indicate.

3 Oct 2013

Multiple aspects to severe bipolar mixed states

Researchers have identified four subgroups of severe bipolar mixed states, characterized by distinct symptomatologic presentations.

1 Oct 2013

Cogstate test shows effective treatment option for schizophrenia

Medical technology company Cogstate continues to strengthen its position as an essential partner for measuring cognition in important studies around the world, with results from a schizophrenia study using Cogstate's test published in a major scientific journal.

27 Sep 2013

Drug misuse predicts protracted hospital stay for schizophrenia patients

Patients hospitalized with schizophrenia have more severe symptoms and spend longer in hospital if they have a concurrent substance use disorder, report researchers.

26 Sep 2013