Pulmonary Fibrosis News and Research

RSS

Study identifies molecular pathway critical to development of fibrosis

A study led by investigators at Massachusetts General Hospital and University Health Network in Toronto has identified a molecular pathway that appears to be critical to the development of fibrosis - scarring and excessive tissue deposition that result from abnormal healing responses and can compromise the function of vital organs.

15 Nov 2017

Health scientists uncover gene linked to lung fibrosis

Health scientists at the University of Leicester and University of Nottingham have heralded the discovery of a gene associated with lung fibrosis as 'a potential new avenue of treatment for further research into this terrible disease.'

23 Oct 2017

Study: 52-gene risk profile accurately predicts survival for patients with severe lung disease

An international Yale-led research team has shown that a risk profile based on 52 genes accurately predicts survival for patients with a severe lung disease. If confirmed in further studies, the finding could transform the way patients are treated for the condition, which is on the rise in older adults.

20 Sep 2017

Detailed understanding of ‘one of the most complex organs’ could provide new ways to treat lung disorders

Details of lung cell molecular pathways that promote or inhibit tissue regeneration were reported by researchers from the Perelmen School of Medicine at the University of Pennsylvania in Cell this week. Their aim is to find new ways to treat lung disorders.

7 Sep 2017

FDA issues warning letter to US Stem Cell Clinic for significant deviations

The U.S. Food and Drug Administration today posted a warning letter issued to US Stem Cell Clinic of Sunrise, Florida, and its Chief Scientific Officer Kristin Comella for marketing stem cell products without FDA approval and for significant deviations from current good manufacturing practice requirements, including some that could impact the sterility of their products, putting patients at risk.

28 Aug 2017

Cellular aging process can promote idiopathic pulmonary fibrosis

Pulmonary fibrosis can possibly be attributed to a kind of cellular aging process, which is called senescence. This has been shown by researchers from the Helmholtz Zentrum München, partner in the German Center for Lung Research.

4 Aug 2017

Researchers develop potential stem cell treatment for several lung conditions

A team of scientists from the UNC School of Medicine and North Carolina State University has developed promising research towards a possible stem cell treatment for several lung conditions, such as idiopathic pulmonary fibrosis (IPF), chronic obstructive pulmonary disease (COPD), and cystic fibrosis -- often-fatal conditions that affect tens of millions of Americans.

3 Aug 2017

New survey reveals emotional, practical challenges facing people with idiopathic pulmonary fibrosis

New results from a global survey supported by Boehringer Ingelheim reveal the emotional and practical challenges facing people with idiopathic pulmonary fibrosis (IPF).

24 Jul 2017

Targeting immune cells could lead to new treatments for pulmonary fibrosis

Northwestern Medicine scientists have demonstrated that a unique population of immune cells plays a key role in the development of pulmonary fibrosis, and showed that targeting such cells could lead to new treatments for the disease.

13 Jul 2017

Loyola Medicine participates in major study of rare lung disease that affects Puerto Ricans

Loyola Medicine is enrolling patients in the first major study of a rare, debilitating lung disease that disproportionately affects people from Puerto Rico.

7 Jul 2017

Keck School of Medicine of USC awarded seven-year NIH grant for research on lung cell regeneration

The Keck School of Medicine of the University of Southern California is one of four institutions in California to receive a multimillion R35 grant from the National Institutes of Health's National Heart, Lung, and Blood Institute in 2017.

5 Jul 2017

New tools can potentially play key role in early diagnosis of systemic sclerosis

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR) 2017 press conference highlight the use of two new tools, which can potentially play a pivotal role in the early diagnosis of Systemic Sclerosis.

14 Jun 2017

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Two T cell biomarkers appear to predict the survival trajectory of patients with idiopathic pulmonary fibrosis (IPF), a lung disease that has a varied, but ultimately devastating, impact on patients, according to new research presented at the ATS 2017 International Conference.

22 May 2017

CUMC researchers create new organoids that mimic features of full-sized lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung- have been created from human pluripotent stem cells by researchers at Columbia University Medical Center. The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

11 May 2017

Researchers find antibody to be effective against radiation-induced fibrosis

Radiation therapy is part of the treatment regimen for about two thirds of cancer patients today. Radiotherapy is well tolerated in most cases, but it can also lead to damage in healthy tissues that are also irradiated.

31 Mar 2017

Review provides new understanding of cytokine mediated effects on inflammatory disorders

Researchers studying chronic inflammation that can lead to the development of lung diseases such as asthma, pulmonary fibrosis, and cancer, are focusing on the role cytokines play in regulating the behavior of fibroblast cells and the extracellular matrix.

24 Mar 2017

Researcher examines scarring process in hope of preventing chronic lung transplant rejection

For patients affected by lung diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease, cystic fibrosis and others, cures for their diseases are incredibly rare, if not nonexistent.

2 Mar 2017

Two thirds of IPF patients report being involved during the decision-making process for the most appropriate treatment

New results from a global survey of over 150 people living with idiopathic pulmonary fibrosis (IPF), a life-threatening rare lung disease, demonstrate that while many patients were involved in treatment decisions, opportunities exist to improve the level of dialogue between patients and healthcare professionals.

28 Feb 2017

Mayo Clinic study finds link between biology of aging and idiopathic pulmonary fibrosis

A Mayo Clinic study has shown evidence linking the biology of aging with idiopathic pulmonary fibrosis, a disease that impairs lung function and causes shortness of breath, fatigue, declining quality of life, and, ultimately, death.

23 Feb 2017

Radiotherapy for breast cancer linked to greater risk of second primary lung cancer

East Asian female breast cancer patients receiving radiotherapy have a higher risk of developing second primary lung cancer.

16 Feb 2017