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Ribonucleic acid (RNA) is a biologically important type of molecule that consists of a long chain of nucleotide units. Each nucleotide consists of a nitrogenous base, a ribose sugar, and a phosphate.

Arizona COVID-19 Genomics Union tracks SARS-CoV-2 genome sequences

Initial findings reported by the Arizona COVID-19 Genomics Union (ACGU) suggest that following Arizona's first reported case of COVID-19 in late January, the state experienced no cases that went undetected and was COVID-free until at least 11 distinct incursions occurred between mid-February and early April.

16 Sep 2020

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

A study on the effectiveness of multiple treatments, including laboratory-made antibodies, at preventing mild COVID-19 from advancing to severe illness in the outpatient setting is underway by researchers at The University of Texas Health Science Center at Houston (UTHealth).

16 Sep 2020

New images capture startlingly high SARS-CoV-2 viral loads

Now, a team of scientists from the University of North Carolina at Chapel Hill School of Medicine produced striking images in respiratory tract cultures of the infectious form of the SARS-CoV-2 produced by infected epithelial cells.

16 Sep 2020

SARS-CoV-2 infection severity linked to superior humoral immunity against the S-protein

In a recent bioRxiv* preprint paper, Jenna J. Guthmiller et al., focus on the acute infection of SARS-CoV-2 and observe that the humoral immunity is distinctive with the infection stage and viral antigens.

16 Sep 2020

SARS-CoV-2 N protein forms biomolecular condensates with viral RNA

Now, a study by researchers from the University of California has shown that the N protein forms biomolecular condensates with the viral RNA in both in vitro and in vivo studies. The research titled, ‘SARS CoV-2 nucleocapsid protein forms condensates with viral genomic RNA’, was published on the preprint server bioRxiv on September 14th, 2020.

15 Sep 2020

Different variants of SARS-CoV-2 identified in San Francisco Bay Area sewage

A team of scientists at the University of California, Berkeley, Innovative Genomics Institute, Illumina, Inc., and Stanford University has performed a genomic sequencing of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) collected from sewage in the San Francisco Bay Area.

15 Sep 2020

Patients with more severe SARS-CoV-2 infection exhibit larger antibody response

Researchers in the United States have found that individuals who develop more severe disease following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mount a larger antibody and memory B cell response during both acute infection and convalescence.

15 Sep 2020

UIC receives $4.5 million to study how adolescent binge drinking affects adult behavior

The University of Illinois Chicago has received $4.5 million in continuation funding from the National Institute on Alcohol Abuse and Alcoholism to support the UIC site of the national Neurobiology of Adolescent Drinking in Adulthood, or NADIA, consortium.

15 Sep 2020

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

Scientists at Sanford Burnham Prebys Medical Discovery Institute, Fondazione Santa Lucia IRCCS, and Università Cattolica del Sacro Cuore in Rome have shown that pharmacological (drug) correction of the content of extracellular vesicles released within dystrophic muscles can restore their ability to regenerate muscle and prevent muscle scarring (fibrosis).

15 Sep 2020

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

In a recently published study, researchers from the Turku Bioscience Centre at the University of Turku and Åbo Akademi University in Finland monitored the production of new proteins as they were produced by the cells' protein building machinery, the ribosome.

15 Sep 2020

New antibody assay for COVID-19 promises sensitive mass-scale detection

A new paper by researchers at McMaster University and Hamilton Health Sciences, published on the preprint server medRxiv in September 2020, reports on the development of a serologic assay that is suitable for sensitive high-throughput antibody testing for COVID-19.

15 Sep 2020

RNA nanoparticles show great promise for targeted delivery of anticancer drugs

A new study by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC - James) shows that RNA nanoparticles have elastic and rubbery properties that help explain why these particles target tumors so efficiently and why they possess lower toxicity in animal studies.

15 Sep 2020

Bath scientists receive funding to monitor wastewater in cities in the UK and Africa

Chemists, biologists and mathematicians from the University of Bath have received funding to monitor wastewater in cities in the UK and Africa, to provide an early warning of the potential spread of COVID-19.

15 Sep 2020

Central nervous system immune responses to COVID-19

A recent study published on the preprint server bioRxiv by scientists from Yale School of Medicine, University of California, Yale School of Public Health, Yale University, and Howard Hughes Medical Institute examined the impact of SARS-CoV-2 infection on the central nervous system.

14 Sep 2020

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Myotonic dystrophy type I is the most common type of adult-onset muscular dystrophy. People with the condition inherit repeated DNA segments that lead to the toxic buildup of repetitive RNA, the messenger that carries a gene's recipe to the cell's protein-making machinery.

14 Sep 2020

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

Breast cancer is the second most common cancer diagnosed in women in the United States after skin cancer, and women with comorbidities (the presence of more than one condition/disease) often fare worse in terms of their breast cancer.

14 Sep 2020

Circadian rhythm affects SARS-CoV-2 infection and host immune response

In an interesting bioRxiv preprint paper, French researchers show that the time day can affect infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as guide subsequent host immune response – implying that circadian rhythm may well be a novel target for managing viral progression.

14 Sep 2020

Keto diet could be beneficial for elderly COVID-19 patients

A recent study by researchers at Yale School of Medicine, New York University Langone Health and Washington University School of Medicine, claims that the ketogenic diet (high fat, low carbohydrate diet) is capable of mitigating clinical outcomes of coronavirus disease 2019 (COVID-19) in elderly people by improving immune-metabolic functions and reducing inflammation. The study is currently available on the bioRxiv* preprint server.

14 Sep 2020

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

HSE University researchers have found microRNA molecules that are potentially capable of repressing the replication of human coronaviruses, including SARS-CoV-2.

14 Sep 2020

Susceptibility of domestic pigs to SARS-CoV-2

A recent study published on the preprint server bioRxiv sought to determine the susceptibility of domestic swine to SARS-CoV-2. Domestic swine is one of the most highly produced agricultural species that has the potential to impact public health significantly.

14 Sep 2020

RNA News and Research

Further Reading

Arizona COVID-19 Genomics Union tracks SARS-CoV-2 genome sequences

Researchers are testing the effectiveness of multiple treatments to prevent COVID-19

New images capture startlingly high SARS-CoV-2 viral loads

SARS-CoV-2 infection severity linked to superior humoral immunity against the S-protein

SARS-CoV-2 N protein forms biomolecular condensates with viral RNA

Different variants of SARS-CoV-2 identified in San Francisco Bay Area sewage

Patients with more severe SARS-CoV-2 infection exhibit larger antibody response

UIC receives $4.5 million to study how adolescent binge drinking affects adult behavior

Study uncovers a promising new therapeutic approach for Duchenne muscular dystrophy

LRRK2 enzyme suppresses protein synthesis in Parkinson’s disease

New antibody assay for COVID-19 promises sensitive mass-scale detection

RNA nanoparticles show great promise for targeted delivery of anticancer drugs

Bath scientists receive funding to monitor wastewater in cities in the UK and Africa

Central nervous system immune responses to COVID-19

RCas9 gene therapy clears toxic RNA buildup in mouse model of myotonic dystrophy

Researchers receive $2.5 million grant to develop and analyze breast tumor organoids

Circadian rhythm affects SARS-CoV-2 infection and host immune response

Keto diet could be beneficial for elderly COVID-19 patients

Researchers identify microRNA molecules that could repress the replication of human coronaviruses

Susceptibility of domestic pigs to SARS-CoV-2

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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