RNA Sequencing News and Research

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New insights into the pathogenesis of chronic liver diseases

Fatty liver diseases (FLD) have become a significant health concern worldwide, affecting millions. The two most common types of FLD are non-alcoholic fatty liver disease (NAFLD) and alcoholic-associated liver disease (ALD). NAFLD is associated with obesity, insulin resistance, and metabolic syndrome, while ALD is caused by excessive alcohol consumption.

7 Nov 2023

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Researchers have mapped the complex epigenetic and transcriptomic landscape of cancer, revealing key regulatory elements across 11 tumor types that could unlock new insights into cancer progression and metastasis.

5 Nov 2023

How to optimize nuclei extraction & counting for single cell sequencing

In this interview, News Medical talks to DeNovix about the best way to prepare nuclei samples before single cell sequencing workflows and optimize nuclei extraction.

From DeNovix Inc. 1 Nov 2023

PacBio announces Kinnex RNA Kits, further scaling HiFi Sequencing in Full-Length RNA, Single-Cell RNA and 16S rRNA applications

PacBio today announced it has begun taking orders for its groundbreaking Kinnex RNA kits, which increase throughput for full-length RNA, single-cell RNA, and 16S rRNA sequencing on PacBio’s long-read sequencing systems to enable large-scale studies at a resolution difficult to attain with short-read RNA sequencing.

From PacBio 1 Nov 2023

Metabolic increase in the hippocampus is early sign of Alzheimer's disease, study finds

An early phase in the process of developing Alzheimer's disease is a metabolic increase in a part of the brain called the hippocampus, report researchers from Karolinska Institutet in a study published in Molecular Psychiatry.

31 Oct 2023

Imperial researchers discover hidden mechanism behind feeling touch

Imperial researchers have discovered a hidden mechanism within hair follicles that allow us to feel touch.

27 Oct 2023

New insights into why obesity puts individuals at risk for severe influenza

The mechanisms underpinning severe cases of influenza among the obese population.

23 Oct 2023

Scientists uncover a group of immune cells that may drive severe asthma in older men

Scientists from La Jolla Institute for Immunology (LJI) and The University of Southampton, UK, have uncovered a group of immune cells that may drive severe asthma.

20 Oct 2023

Researchers identify new biomarker to predict neuronal regeneration after injury

Neurons, the main cells that make up our brain and spinal cord, are among the slowest cells to regenerate after an injury, and many neurons fail to regenerate entirely.

16 Oct 2023

New nanocapsule treatment boosts immune response against solid tumors

UCLA researchers have developed a new treatment method using a tiny nanocapsule to help boost the immune response, making it easier for the immune system to fight and kill solid tumors.

11 Oct 2023

DNA aptamers: A versatile tool for regenerative medicine and beyond

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

10 Oct 2023

Progress and challenges in completing the human gene catalogue

A group of authors reviewed the progress and challenges in annotating the human genome, including protein-coding genes, isoforms, and non-coding RNAs, and advocated for a universal annotation standard for clinical use.

5 Oct 2023

New zebrafish xenograft platform could help screen for glioblastoma treatments

Scientists have created a new zebrafish xenograft platform to screen for novel treatments for an aggressive brain tumor called glioblastoma, according to a new study by the Gerhardt and De Smet labs published in EMBO Molecular Medicine.

4 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Researchers reported that the increased long-term risk of acute cardiovascular complications associated with COVID-19 is linked to SARS-CoV-2 infecting coronary vessels and inducing the formation of plaques.

3 Oct 2023

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Micro-ribonucleic acids (miRNAs) linked to cognition and Alzheimer's disease (AD).

3 Oct 2023

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

The organisms that cause visceral leishmaniasis, a potentially deadly version of the parasitic disease that most often affects the skin to cause disfiguring disease, appear to have a secret weapon, new research suggests: They can infect non-immune cells and persist in those uncommon environments.

29 Sep 2023

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Researchers have developed BigRNA, a groundbreaking deep learning model capable of predicting RNA behavior, including tissue-specific expression and splicing, directly from genomic DNA sequences. The model excels in identifying pathogenic variants and could be a game-changer in the development of personalized RNA-based therapies for treating genetic diseases.

28 Sep 2023

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Alzheimer's disease affects more than 6 million people in the United States, and there are very few FDA-approved treatments that can slow the progression of the disease.

28 Sep 2023

Researchers develop new way to boost immune cells' ability to fight TB

Tuberculosis is old-;ancient even. The infectious bacterial disease that plagued Old Testament Israelites and took down pharaohs was eventually stunted by vaccinations, antibiotics, and public health measures like isolation, but it hasn't been cured yet.

27 Sep 2023

RNA Sequencing News and Research

New insights into the pathogenesis of chronic liver diseases

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

How to optimize nuclei extraction & counting for single cell sequencing

PacBio announces Kinnex RNA Kits, further scaling HiFi Sequencing in Full-Length RNA, Single-Cell RNA and 16S rRNA applications

Metabolic increase in the hippocampus is early sign of Alzheimer's disease, study finds

Imperial researchers discover hidden mechanism behind feeling touch

New insights into why obesity puts individuals at risk for severe influenza

Scientists uncover a group of immune cells that may drive severe asthma in older men

Researchers identify new biomarker to predict neuronal regeneration after injury

New nanocapsule treatment boosts immune response against solid tumors

DNA aptamers: A versatile tool for regenerative medicine and beyond

Progress and challenges in completing the human gene catalogue

New zebrafish xenograft platform could help screen for glioblastoma treatments

Could infants' robust immune responses reshape future vaccination strategies?

SARS-CoV-2 infection in coronary vessels linked to cardiovascular complications

Identification of Alzheimer's disease-associated micro-RNA biomarkers through network-based analysis

Parasites that cause visceral leishmaniasis can infect non-immune cells, study finds

Unlocking the code: BigRNA's deep learning model predicts RNA behavior

Study reveals a complex interplay of genetic and epigenetic changes in Alzheimer’s disease progression

Researchers develop new way to boost immune cells' ability to fight TB

Sequencing & Genomics: Elevating Science and Healthcare eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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