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Women may be more vulnerable to drug addiction and addiction-like behaviors than men

The results of several new studies focusing on sex differences in pain and addiction indicate females could be more susceptible to drug addiction and addiction-like behaviors than males. Researchers also explored the role of lack of sleep on the likeliness to relapse. This is due in part to hormone differences in females and males. Data from the studies will be presented virtually October 19–22 at the American Physiological Society's seventh conference on New Trends in Sex and Gender Medicine.

20 Oct 2021

New SBIR award helps Temple scientists to explore the therapeutic potential of novel cannabis analog

More than 20 percent of adults in the United States live with chronic pain. For many affected individuals, long-term physical discomfort negatively impacts overall well-being, leading to reduced work output and increased anxiety and depression.

29 Sep 2021

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

A research team from the Universitat Autònoma de Barcelona has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio A disease.

12 Sep 2021

Mutated enzyme impairs communication between neurons and causes motor defects in SCA34 model

In one type of a rare, inherited genetic disorder that affects control of body movement, scientists have found a mutation in an enzyme that impairs communication between neurons and what should be the inherent ability to pick up our pace when we need to run, instead of walk, across the street.

17 Aug 2021

E-cigarette use during pregnancy poses health risk for offspring all the way into adulthood

The use of e-cigarettes (vaping) during pregnancy poses a significant health risk for the offspring, impairing blood vessel function even into adulthood, according to a new study by researchers at West Virginia University's School of Medicine.

5 Aug 2021

Study opens the door to improved treatment for psychosis sufferers

University of Otago scientists have opened the door to improved treatment of brain dysfunction which causes psychosis.

15 Jul 2021

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

The RDM Positive Impact Foundation is funding an ambitious $1.25 million research project at the UC Davis MIND Institute to study SYNGAP1.

22 Jun 2021

Study reveals how HIV prevents the maturation of myelin-making brain cells

It's long been known that people living with HIV experience a loss of white matter in their brains. As opposed to "gray matter," which is composed of the cell bodies of neurons, white matter is made up of a fatty substance called myelin that coats neurons, offering protection and helping them transmit signals quickly and efficiently.

2 Jun 2021

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

Scientists have revealed a potential mechanism for how traumatic brain injury leads to neurodegenerative diseases, according to a study in fruit flies, and rat and human brain tissue, published today in eLife.

1 Jun 2021

New cocaine and oxycodone biobanks provide investigatory therapeutic targets for addiction

A major hurdle to developing new and effective treatments for drug addiction is better understanding how exactly it manifests itself before, during and after chronic use.

26 Apr 2021

Fixing traumatic injuries to the skin and bones using bioprinting during surgery

Fixing traumatic injuries to the skin and bones of the face and skull is difficult because of the many layers of different types of tissues involved, but now, researchers have repaired such defects in a rat model using bioprinting during surgery, and their work may lead to faster and better methods of healing skin and bones.

26 Apr 2021

New exosome-coated stent repairs damaged tissue, heals vascular injury

Researchers from North Carolina State University have developed an exosome-coated stent with a "smart-release" trigger that could both prevent reopened blood vessels from narrowing and deliver regenerative stem cell-derived therapy to blood-starved, or ischemic, tissue.

6 Apr 2021

$Researchers move one step closer to preventing limb deformities from childhood fractures$

Researchers move one step closer to preventing limb deformities from childhood fractures

Orthopedic researchers are one step closer to preventing life-long arm and leg deformities from childhood fractures that do not heal properly.

25 Mar 2021

UTMB researchers pioneer a new way to study frustration as a factor in substance use disorders

A team from The University of Texas Medical Branch at Galveston (UTMB) focused on drug addiction research have pioneered a new way to study frustration as a factor in substance use disorders.

1 Mar 2021

Researchers develop new tool for tackling disseminated intravascular coagulation

Researchers have developed a new tool for addressing disseminated intravascular coagulation (DIC) - a blood disorder that proves fatal in many patients.

17 Feb 2021

Cell-selective nanotherapy can help treat atherosclerotic plaques

Percutaneous coronary intervention (PCI), commonly known as angioplasty with a stent, opens clogged arteries and saves lives. Despite its benefit in treating atherosclerosis that causes coronary artery disease, this common minimally-invasive procedure still poses severe complications for some patients.

11 Feb 2021

Rat Model News and Research

Women may be more vulnerable to drug addiction and addiction-like behaviors than men

New SBIR award helps Temple scientists to explore the therapeutic potential of novel cannabis analog

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

Mutated enzyme impairs communication between neurons and causes motor defects in SCA34 model

E-cigarette use during pregnancy poses health risk for offspring all the way into adulthood

Study opens the door to improved treatment for psychosis sufferers

RDM Positive Impact Foundation funds $1.25 million research project to study SYNGAP1

Study reveals how HIV prevents the maturation of myelin-making brain cells

Study reveals potential mechanism for how traumatic brain injury leads to neurodegenerative diseases

New cocaine and oxycodone biobanks provide investigatory therapeutic targets for addiction

Fixing traumatic injuries to the skin and bones using bioprinting during surgery

New exosome-coated stent repairs damaged tissue, heals vascular injury

Researchers move one step closer to preventing limb deformities from childhood fractures

UTMB researchers pioneer a new way to study frustration as a factor in substance use disorders

Researchers develop new tool for tackling disseminated intravascular coagulation

Cell-selective nanotherapy can help treat atherosclerotic plaques

New contraceptive gel contains spermicidal, anti-viral, libido-enhancing agents in one formulation

Newly designed Biomesh minimizes postsurgical complications of hernia repair

Novel MRI contrast agent shows strong potential as safer alternative to current products

USask researchers to study how cannabis use during pregnancy affects fetus' brain development

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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