Respiratory News and Research

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How replication and recombination contribute to emergence of SARS-CoV-2 variants

The coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of a novel coronavirus, namely, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). SARS-CoV-2 was first reported in late December 2019 in Wuhan, China. Since then, the virus has already claimed more than 4.3 million lives worldwide.

13 Aug 2021

Research debunks myth that COVID vaccination promotes mutations

A study conducted by researchers at the University of Maryland, USA, has highlighted the importance of coronavirus disease 2019 (COVID-19) vaccination in reducing the frequency of mutations in the delta variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

13 Aug 2021

SARS-CoV-2 variants containing L452R spike mutation more resistant to antibody-mediated neutralization

A team of scientists from Frankfurt, Germany, has recently explored the efficacy of vaccine- or infection-induced antibodies and therapeutic monoclonal antibodies in neutralizing kappa and delta variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Aug 2021

Camelid nanobody anti-SARS-CoV-2 drug candidates

In a research paper recently published in the journal eLife, researchers from several US institutions have developed a nanobody-based candidate drug that effectively prevents and suppresses severe SARS-CoV-2 infection in animals.

12 Aug 2021

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

How do viruses reorganize host cells with spatial and molecular specificity? Researchers from the Netherlands provided new insights in a recent study posted to the bioRxiv* preprint server, where they use optical nanoscopy to look at severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-triggered changes in primary human airway cells.

12 Aug 2021

FDA approves a new indication for chronic sleep disorder treatment

The U.S. Food and Drug Administration today approved a new indication for Xywav for idiopathic hypersomnia (IH) in adults.

12 Aug 2021

PAHO Director expresses concern about COVID-19 vaccine hesitancy in Caribbean countries

Dr. Carissa F. Etienne, Director of the Pan American Health Organization (PAHO), expressed concern about COVID-19 vaccine hesitancy in Caribbean countries and made a strong appeal to people to get vaccinated.

12 Aug 2021

Reading, ’rithmetic and resisting covid: The new 3 R’s as kids head back to school

When kids head back to school this fall, for some it will be the first time they've been in a real classroom with other students since the pandemic began.

12 Aug 2021

SARS-CoV-2 detection by machine learning surface-enhanced Raman spectroscopy

Surface-enhanced Raman spectroscopy is a highly sensitive molecule characterization method, significantly more sensitive than ordinary Raman spectroscopy due to the excitation of Raman modes matching the plasmon resonance frequency of the surface metal utilized, usually gold, silver, or copper.

11 Aug 2021

VPS29 gene facilitates coronavirus cell entry

In a research paper recently uploaded to the bioRxiv* preprint server by Poston et al. (August 8th, 2021), common host factors amongst several zoonotic pathogens are explored by CRISPR-Cas9 screening in human lung cells, focusing in particular on the betacoronavirus genus.

11 Aug 2021

Ten-fold reduced risk of workplace SARS-CoV-2 infection in seropositive essential workers

A reassuring new study supports the opening of workplaces to seropositive workers in view of the extremely low risk of reinfection observed in this cohort.

11 Aug 2021

COVID-19 risks likely to shift from older adults to younger children

Within the next few years, as the SARS-CoV-2 virus becomes endemic in the global population, COVID-19 may behave like other common-cold coronaviruses, affecting mostly young children who have not yet been vaccinated or exposed to the virus, according to new modeling results.

11 Aug 2021

Immunogenicity of mRNA vaccine against emerging strains of SARS-CoV-2 in immunocompromised patients

A study measured neutralization of SARS-CoV-2 and vaccine responses in immunocompromised patients with systemic inflammatory diseases.

11 Aug 2021

Researchers quantify left-over COVID vaccine in used Pfizer-BioNTech vials

A new observational study, published on medRxiv* preprint server, has evaluated the unused residual Pfizer-BioNTech vaccine in vials. Bainbridge Prepares (BP), an organization consisting of community medical and non-medical volunteers, supported the research.

11 Aug 2021

Norwegian study on the benefits of COVID vaccination for residents and employees in nursing homes

It is important to understand the vaccine effectiveness (VE) to determine how much protection it offers to the general population. Unfortunately, only a few studies are available that have determined the effect of the COVID-19 vaccine among the residents of LTCFs.

11 Aug 2021

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

In the current study, the authors evaluate several different competitive ELISAs that could be used to measure serum antibodies.

11 Aug 2021

Risk factors for hospitalization among HIV patients infected with SARS-CoV-2

The hospitalization of PWH with COVID-19 is related to host factors such as older age and co-morbidities, rather than due to traditional metrics of HIV.

11 Aug 2021

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

A recent study discusses the clinical characteristics and outcomes of patients with SARDs who were previously vaccinated against SARS-CoV-2.

11 Aug 2021

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

The coronavirus disease 2019 (COVID-19) has been thought to spread primarily when an infected person coughs or sneezes, but little is known about its transmissibility through activities such as breathing, talking, and singing.

11 Aug 2021

In Australia, high vaccine hesitancy among most vulnerable to COVID-19

World Health Organization (WHO) guidelines indicate the optimal timing of vaccination among specific groups based on the probability of infection and transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), e.g., health care workers providing direct care or acute disease and death (e.g., older people, organ transplant recipients).

11 Aug 2021

Respiratory News and Research

How replication and recombination contribute to emergence of SARS-CoV-2 variants

Research debunks myth that COVID vaccination promotes mutations

SARS-CoV-2 variants containing L452R spike mutation more resistant to antibody-mediated neutralization

Camelid nanobody anti-SARS-CoV-2 drug candidates

Optical nanoscopy reveals how SARS-CoV-2 infection alters human airway cells

FDA approves a new indication for chronic sleep disorder treatment

PAHO Director expresses concern about COVID-19 vaccine hesitancy in Caribbean countries

Reading, ’rithmetic and resisting covid: The new 3 R’s as kids head back to school

SARS-CoV-2 detection by machine learning surface-enhanced Raman spectroscopy

VPS29 gene facilitates coronavirus cell entry

Ten-fold reduced risk of workplace SARS-CoV-2 infection in seropositive essential workers

COVID-19 risks likely to shift from older adults to younger children

Immunogenicity of mRNA vaccine against emerging strains of SARS-CoV-2 in immunocompromised patients

Researchers quantify left-over COVID vaccine in used Pfizer-BioNTech vials

Norwegian study on the benefits of COVID vaccination for residents and employees in nursing homes

Evaluation of mRNA vaccine responses with a surrogate SARS-CoV-2 viral neutralization assay

Risk factors for hospitalization among HIV patients infected with SARS-CoV-2

Breakthrough SARS-CoV-2 infections in patients with systemic rheumatic diseases

Fine aerosols generated during talking, singing may play a major role in SARS-CoV-2 transmission

In Australia, high vaccine hesitancy among most vulnerable to COVID-19

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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