Respiratory News and Research

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Patient laments on not getting the COVID-19 vaccine

Saul Torres considers himself lucky to be alive after contracting COVID-19 and suffering from a rare neurological condition.

10 Aug 2021

Researchers look into the effects of particle contaminants on mucosal system

Major disruptions to our health and quality of life are front of mind in an era when wildfires, floods, and the ongoing COVID-19 pandemic impact Earth's population daily.

10 Aug 2021

Study explores ‘brain fog’ following COVID-19

A recent survey conducted in the United Kingdom revealed that approximately one in every five experiences prolonged coronavirus disease 2019 (COVID-19) symptoms five weeks post-infection. Also, one in seven people reported persistent symptoms even after twelve weeks.

10 Aug 2021

Cardioprotective role of HIF1α in COVID-19 patients

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first emerged in Wuhan, China, in late December 2019, has quickly become the most urgent issue facing scientists worldwide. It has been reported that the respiratory infection causes cardiac dysfunction in 25-55% patients, including hospitalized patients and non-critical patients.

10 Aug 2021

SARS-CoV-2 Iota variant increases mortality risk among older adults

The findings reveal that the variant has considerably higher transmissibility and immune escape potential than previously circulating variants and that it can increase the infection fatality rate by 62% - 82% among older adults. The study is currently available on the medRxiv* preprint server.

10 Aug 2021

SARS-CoV-2 variants and their ability to infect mice

A new study published on the bioRxiv* preprint server has conducted in silico studies along with in vitro, in vivo, and in situ observations and indicated the mouse adaptation of SARS-CoV-2.

10 Aug 2021

Evaluation of COVID-19 risk among international travelers in the UK for safety purposes

A high risk of transmission of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, is associated with international travel.

9 Aug 2021

New protocol for the study of SARS-CoV-2's medium and long-term outcomes

The clinical symptoms of the severe COVID-19 have been well described. In addition, scientists have defined the post-acute COVID-19 as the development of sequelae or persistence of symptoms several weeks after the onset of COVID-19 symptoms. In some cases, the symptoms persist for around 3-4 weeks, and in other cases of chronic COVID-19, symptoms may persist beyond 12 weeks from the onset of symptoms.

9 Aug 2021

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

A recent study in Colorado used real-world data to evaluate if individuals with chronic conditions have reduced antibody response to COVID-19 mRNA vaccines. The study investigated whether some medical conditions may impact antibody response to the mRNA vaccines.

9 Aug 2021

Controlling the spread of SARS-CoV-2 at a large public university

Researchers from the U.S. recently reported a multimodal "SHIELD: Target, Test, and Tell" program that helped mitigate the transmission of SARS-CoV-2 at a large public university. The program also prevented community transmission and helped the continuation of in-person classes during the pandemic. This study is available on the medRxiv* preprint server.

9 Aug 2021

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

A new study describes the cytopathic episodes triggered by SARS-CoV-2 with virus replication processes in frozen-hydrated cells.

9 Aug 2021

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

A new study has explored a series of potential flavonoid inhibitors targeting 3CL protease of SARS-CoV.

9 Aug 2021

Young, healthy adult infected by COVID-19 suffers CNS lymphocytic vasculitis

Although COVID-19 is primarily treated as a respiratory disease, patients often experience neurological problems, such as headaches, anxiety, depression and cognitive issues, which can persist long after other symptoms have resolved.

9 Aug 2021

Expert panel recommends standardized criteria to define placental SARS-CoV-2 infection

A panel of experts convened by the National Institutes of Health has recommended standardized criteria to define infection of the placenta with SARS-CoV-2, the virus that causes COVID-19.

9 Aug 2021

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

In addition to clinical trials conducted to determine the safety and efficacy of the mRNA vaccines, additional studies began describing the serological response to the vaccines under "real-world" conditions, especially with the onset of the SARS-CoV-2 variants and case reports of vaccine escape.

9 Aug 2021

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

The spike protein comprises of two subunits: S1 subunit having the receptor-binding domain (RBD) that helps it to bind to the angiotensin-converting enzyme 2 (ACE2), which is present on the cell surface of the host, and the S2 subunit that helps in the fusion of the cellular membrane and the viral membrane.

9 Aug 2021

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

A group of medications long prescribed to treat tapeworm has inspired a compound that shows two-pronged effectiveness against COVID-19 in laboratory studies, according to a new publication appearing online in the journal ACS Infectious Disease.

9 Aug 2021

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

A team of US-based scientists has recently conducted a robust high-throughput screening to identify potential entry inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The screening identifies calpeptin as a potent and highly specific inhibitor of SARS-CoV-2 and its variants. The study is currently available on the bioRxiv* preprint server.

9 Aug 2021

Cetylpyridinium chloride-containing mouthwashes shown to inhibit SARS-CoV-2 in oral cavity

A team of international scientists has recently demonstrated the usefulness of cetylpyridinium chloride-containing mouthwashes in inhibiting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and reducing the risk of viral transmission. The study is currently available on the bioRxiv* preprint server.

9 Aug 2021

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

By retrieving 329,942 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) records from the GISAID database, researchers from a software company in Cambridge described genetic variability of SARS-CoV-2 in order to inform further studies. Their findings are currently available on the bioRxiv* preprint server while it undergoes peer review.

9 Aug 2021

Respiratory News and Research

Patient laments on not getting the COVID-19 vaccine

Researchers look into the effects of particle contaminants on mucosal system

Study explores ‘brain fog’ following COVID-19

Cardioprotective role of HIF1α in COVID-19 patients

SARS-CoV-2 Iota variant increases mortality risk among older adults

SARS-CoV-2 variants and their ability to infect mice

Evaluation of COVID-19 risk among international travelers in the UK for safety purposes

New protocol for the study of SARS-CoV-2's medium and long-term outcomes

Study shows impaired SARS-CoV-2 mRNA vaccine antibody response in individuals with chronic conditions

Controlling the spread of SARS-CoV-2 at a large public university

A multi-scale cryo-correlative platform to image SARS-CoV-2 in Vero cells

Flavonoid-based inhibitors targeting SARS-CoV 3CL protease for the treatment of SARS-CoV-2 infection

Young, healthy adult infected by COVID-19 suffers CNS lymphocytic vasculitis

Expert panel recommends standardized criteria to define placental SARS-CoV-2 infection

Study of antibody responses to COVID-19 mRNA vaccine in convalescent individuals

Research shows how SARS-CoV-2 variants are evolving towards increased furin cleavage efficiency

New compound inspired by tapeworm drugs shows two-pronged effectiveness against COVID-19

Scientists identify calpeptin as potential inhibitor of SARS-CoV-2

Cetylpyridinium chloride-containing mouthwashes shown to inhibit SARS-CoV-2 in oral cavity

Computational study identifies key areas of the SARS-CoV-2 genome prone to mutation

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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