Sedative News and Research

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A sedative is a substance that induces sedation by reducing irritability or excitement.

Innovative care model for children with ASD reduces use of behavioral drugs in ED

An innovative care model developed by Nemours Children's Hospital for children with autism spectrum disorders in the emergency department reduces the use of medication administered to kids who are prone to stress and sensory overload in this care setting.

11 Dec 2018

Many primary care doctors are still prescribing sedative drugs for older adults

Despite years of warnings that older adults shouldn't take sedative drugs that put them at risk of injury and death, a new study reveals how many primary care doctors are still prescribing them, how often, and exactly where.

19 Oct 2018

Purdue researchers develop new chemical process to find better drug 'fits' for patients

When a medication doesn't "fit" the body quite right, the results can be devastating. Such is the case for thalidomide, which was prescribed in the 1950s and 1960s as a sedative or hypnotic, even for pregnant women.

16 Oct 2018

Adding energy drinks to alcohol may exacerbate negative effects of binge drinking

A key ingredient of energy drinks could be exacerbating some of the negative effects of binge drinking according to a new study.

14 Aug 2018

‘No one is ever really ready’: Aid-in-dying patient chooses his last day

In the end, it wasn't easy for Aaron McQ to decide when to die. The 50-year-old Seattle man — a former world traveler, triathlete and cyclist — learned he had leukemia five years ago, followed by an even grimmer diagnosis in 2016: a rare form of amyotrophic lateral sclerosis, or ALS.

14 Aug 2018

High opioid doses, concurrent sedative use are key factors for overdose risk in Medicaid recipients

Among Medicaid recipients taking prescription opioids, high opioid doses and concurrent treatment with benzodiazepine sedatives are among the key, potentially modifiable risk factors for fatal overdose, reports a study in the August issue of Medical Care.

13 Jul 2018

Study using i2b2 could help standardize artificial coma treatment for RSE patients

Status epilepticus, a dangerous condition in which epileptic seizures follow one another for a duration of five or more minutes without the victim's regaining consciousness between them, is the second most common neurological emergency in the United States, with a recorded maximum of around 150,000-plus cases per year.

30 Jun 2018

UT Southwestern study reveals structural information for major brain receptor

UT Southwestern researchers today published the first atomic structure of a brain receptor bound to a drug used to reverse anesthesia and to treat sedative overdoses.

28 Jun 2018

Overdose risk increases five-fold with concurrent opioid and benzodiazepine use

In the first 90 days of concurrent opioid and benzodiazepine use, the risk of opioid-related overdose increases five-fold compared to opioid-only use among Medicare recipients, according to a new study from the University of Pittsburgh School of Pharmacy, published today in JAMA Network Open

22 Jun 2018

Study: Effective intervention can reduce medication overuse in aged care facilities

Effective intervention can reduce medication overuse in Residential Aged Care Facilities, the latest University of Tasmania research shows.

14 May 2018

Early discharge of infants with neonatal abstinence syndrome may prolong their treatment, shows study

Infants who are diagnosed with drug withdrawal after birth who are treated with medication as outpatients at home are treated three times longer than infants treated solely as inpatients, according to a new Vanderbilt study

10 May 2018

Australian paramedics find new drug to quickly and safely calm violent patients

Australian paramedics are leading the world by introducing a new drug, droperidol, to quickly and safely calm violent patients fueled by alcohol and drugs.

2 May 2018

Children with autism more likely to be prescribed antipsychotic medication, study finds

A new study by Swansea University has suggested that children with intellectual difficulty or autism are more likely to be given antipsychotic medication from a younger age than those without intellectual disability and have higher rates of hospitalization for depression and for injury and also are at risk of other medical side effects.

4 Apr 2018

Researchers explore ways to help older adults taper off and stop using sedatives

Older adults, especially those who are admitted to hospitals, are at risk for potentially dangerous side effects if they are taking multiple medicines. Taking several medications at the same time is called polypharmacy.

23 Mar 2018

Desymmetrization paves way for new bioactive compounds

Many chemical molecules can exist in nature together with their mirror counterparts; like hands, two compounds can be made up of the same atoms in the same overall structure but in opposite orientations, i.e. left-handed and right-handed.

23 Feb 2018

FDA warning against Kratom strengthened

The U.S. Food and Drug Administration (FDA) has amped up its warnings against popular herbal drug kratom. The new warning mentions the deadly risks associated with kratom including a case of a teenager who hanged himself under influence.

8 Feb 2018

Cannabis Quality and Contamination Testing

Dr. Bob Clifford has published and presented over 125 papers in the fields of food, pharmaceutical, environmental, energy, geology, material science, photonics, and cannabis. However, his true love is in food. After graduating with his Ph.D., he left his job with the FDA for Shimadzu where he has worked for the last 26 years.

From Pittcon 5 Feb 2018

Valproic acid exposure results in characteristics linked to autism, zebrafish study shows

Exposure to a compound used to treat migraines and seizures causes characteristics associated with autism, groundbreaking research with zebrafish has demonstrated.

24 Jan 2018

New tool developed to assess likely risk of drug turning into potentially harmful version

A new method to test the likelihood of a drug turning into a potentially harmful version of itself when it enters the body has been developed by researchers at Cardiff University.

5 Jan 2018

Ketamine can stop suicidal thoughts finds new study

A study has shown that Ketamine – an anesthetic drug, is capable of reducing and halting suicidal thoughts in depressed patients. The study comes from Columbia University Medical Center (CUMC) who found that it may take only a few hours after administration of ketamine to reduce the suicidal thoughts in the patients.

18 Dec 2017