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Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Man takes 217 COVID vaccines with no ill effects, shows immune boost

A case report of a 62-year-old man receiving 217 SARS-CoV-2 vaccinations over 29 months reveals no adverse effects, increased T-cells, and spike-specific antibodies, providing unique insights into the effects of hyper-vaccination on immune responses.

7 Mar 2024

Elevated IFN-γ levels linked to long COVID, study finds

Researchers find elevated IFN-γ levels in long COVID patients, with symptom improvement correlating with decreased IFN-γ, suggesting it as a potential biomarker and target for therapeutic intervention.

22 Feb 2024

Syphilis: A silent epidemic reawakens

Study reports a significant increase in syphilis cases in India, highlighting the need for effective prevention and treatment despite the availability of effective therapies.

31 Jan 2024

BNT162b2 vaccine effectiveness in preventing SARS-CoV-2 infection and severe disease

The BNT162b2 vaccine’s effectiveness in preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

11 Jan 2024

UVA biomedical engineer unveils hidden immune symphony during pregnancy

Sepideh Dolatshahi, an assistant professor of biomedical engineering at the University of Virginia, is spearheading an exploration of systems immunology in its crucial development phase -; during pregnancy.

15 Dec 2023

Wood cookstove use linked to gastric cancer risk

Researchers conducted a population-based study with a case–control design in rural areas of Honduras in Central America to examine whether wood cookstove use by indigenous populations was associated with increased risk of stomach cancers, including gastric adenocarcinoma.

4 Oct 2023

Zoonotic spillover safeguarding: computationally designed antigen targets range of coronaviruses

Researchers used an interdisciplinary approach incorporating phylogenetics, 3D protein modeling, and plasmid design to identify and computationally design an antigen representing the core of most currently known sarbecoviruses.

27 Sep 2023

Is the coadministration of a COVID-19 vaccine with a seasonal influenza vaccine safe and efficacious?

Researchers investigated the comparative efficacy and safety of the simultaneous COVID-19 and seasonal influenza vaccination regimen compared to SARS-CoV-2 vaccination alone among healthcare workers who had received one or two COVID-19 booster doses.

12 Sep 2023

Onset and prognosis of post-COVID-19 condition: A 2-Year observational study

Researchers conducted a prospective cohort analysis over two years.

8 Sep 2023

Immune cells present in people months before influenza infection, finds study

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

Potential of COVID-19 convalescent plasma for future monoclonal antibodies against severe SARS-CoV-2 inflammation

Researchers report that convalescent plasma treatment is most effective in treating hospitalized COVID-19 patients.

17 Aug 2023

The protective effect of previous infections and vaccinations on SARS-CoV-2 Omicron infection

Researchers estimate the protective effect of hybrid immunity on infection with the SARS-CoV-2 Omicron variant.

14 Aug 2023

The association of long-term air pollution exposure with SARS-CoV-2 infection

Researchers investigated the association between air quality and risk of SARS-CoV-2 infection.

4 Aug 2023

NIAID funds research to better understand Post-treatment Lyme Disease Syndrome

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded five projects for research to better understand Post-treatment Lyme Disease Syndrome (PTLDS), which is a collection of symptoms, such as pain, fatigue, and difficulty thinking or "brain fog," which linger following standard treatment for Lyme disease.

21 Jul 2023

The infection connection: investigating the impact on dementia risk, neuroimaging reveals

Researchers compared the association between neuroimaging markers of dementia and antibodies to common infection.

17 Jul 2023

New research shows antibody cross-reactivity between human and animal coronaviruses

Researchers probed for antibody binding against all seven human coronaviruses (hCoVs).

27 Jun 2023

MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome.

8 Jun 2023

Link confirmed: Infant RSV infections increase likelihood of childhood asthma

Research investigates the association between early-life respiratory syncytial virus (RSV) infection and the development of childhood asthma. It aims to assess the impact of RSV infection during infancy on the onset of wheezing illnesses and asthma in children.

30 May 2023

Top-Down Proteomics: Bridging the Genotype-to-Phenotype Gap

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to this year's recipient of the Pittsburgh Analytical Chemistry Award, Neil Kelleher, about his work in top-down proteinomics.

From Pittcon 26 May 2023