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Sesame oil supplementation: a potential breakthrough in postmenopausal osteoporosis prevention?

Daily sesame oil supplementation in ovariectomized rats was found to prevent osteoporosis by enhancing bone formation, reducing bone resorption, and maintaining serum estrogen and aromatase levels.

7 Jan 2024

Prevention of post-menopausal osteoporosis in rats by sesame oil

Study demonstrates that daily supplementation with sesame oil in a rat model effectively prevents post-menopausal osteoporosis by maintaining serum estrogen and aromatase levels, suggesting its potential as a safer alternative to hormone replacement therapy.

4 Jan 2024

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Over the past decades, scientists have made substantial progress unveiling the underlying mechanisms behind many psychiatric disorders.

4 Jan 2024

Study sheds light on enzyme's role in advanced prostate cancer progression

Prostate cancer is the most common cancer in men other than skin cancer, and more than 288,000 new cases are diagnosed every year, according to the American Cancer Society.

21 Dec 2023

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Study reveals that cytoglobin (cygb2) plays a crucial role in regulating cilia motility and organ laterality during development, highlighting its importance in NO signaling and cilia function.

19 Dec 2023

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Colorectal cancer presents with varying clinical characteristics due to tumor heterogeneity. Microsatellite instability (MSI), present in 10%-15% of CRC cases, indicates a different clinical trajectory than microsatellite stable (MSS) patients.

15 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Carrot juice boosts immune response, cuts inflammation, new study reveals

A study in the journal Nutrients by Danish researchers shows that consuming carrot juice, rich in falcarinol and falcarindiol, influences acute inflammatory mediators and innate immune responses in human blood.

4 Dec 2023

The effects of vitamin K on bone health

Existing scientific data on the effects of vitamin K (VK) on bone health and elucidated the underlying mechanisms.

30 Nov 2023

Study uncovers cell signaling pathway that regulates melanoma brain metastasis

Melanoma is the deadliest form of skin cancer because of its ability to quickly grow and spread throughout the body.

29 Nov 2023

RNA-based therapy shows promise for treating leukemia in animal models

Each year, about 13,000 people in Deutschland are diagnosed with leukemia, an umbrella term that encompasses various forms of blood cancer.

27 Nov 2023

New signaling mechanism implicated in the development of ventricular fibrillation

A study led by Guadalupe Sabio and José Jalife at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid has identified a new signaling mechanism implicated in the development of ventricular fibrillation, a type of arrhythmia, or irregular heartbeat.

27 Nov 2023

The future of functional foods: Leveraging Dendrobium officinale for optimal gut health and disease prevention

The structure, extraction, health benefits, and mechanisms of Dendrobium officinale polysaccharides (DOPs).

27 Nov 2023

Mendelian randomization reveals a causal relationship between diabetes mellitus and pancreatic cancer

Announcing a new article publication for BIO Integration journal. This study investigates the association between diabetes mellitus and susceptibility to pancreatic cancer by using Mendelian randomization (MR) methods and an extensive human genome-wide association study (GWAS) dataset.

23 Nov 2023

Microautophagy plays crucial role in lysosome repair, promoting healthy aging

To age or not to age! How does aging affect organisms on a cellular level? What mechanisms help cells survive self-inflicted or external harm? It is known that lysosomes-;critically important cellular structures-;are crucial for digesting damaged cellular components and pathogens, and maintain stability within cells and tissues.

21 Nov 2023

Bacteria fight phages with RNA-based immune defense

There's no organism on earth that lives free of threat-;including bacteria. Predatory viruses known as phages are among their most dire foes, infiltrating their cells to replicate and take over.

15 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

Signaling Pathway News and Research

Sesame oil supplementation: a potential breakthrough in postmenopausal osteoporosis prevention?

Prevention of post-menopausal osteoporosis in rats by sesame oil

IDO2 deficiency in mice leads to behavioral abnormalities resembling autism spectrum disorder

Study sheds light on enzyme's role in advanced prostate cancer progression

Study reveals cytoglobin's pivotal role in cilia movement and organ positioning during development

Wnt signaling holds promise for tailored immunotherapy in microsatellite-instable colorectal cancer

Study explores the intricate gut-brain-liver connection and its impact on health

Carrot juice boosts immune response, cuts inflammation, new study reveals

The effects of vitamin K on bone health

Study uncovers cell signaling pathway that regulates melanoma brain metastasis

RNA-based therapy shows promise for treating leukemia in animal models

New signaling mechanism implicated in the development of ventricular fibrillation

The future of functional foods: Leveraging Dendrobium officinale for optimal gut health and disease prevention

Mendelian randomization reveals a causal relationship between diabetes mellitus and pancreatic cancer

Microautophagy plays crucial role in lysosome repair, promoting healthy aging

Bacteria fight phages with RNA-based immune defense

Charting the future of IBD treatment: From immune modulators to microRNA therapies

Proteomic study pinpoints potential biomarkers for long-COVID diagnosis and persistent health impacts

Yabing Chen receives NIH grants to advance vascular disease research

New mechanism discovered for aspirin's cancer-fighting properties

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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