Small Molecules News and Research

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Exploring the World of RNA Chemistry

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Philip Bevilacqua from Pennsylvania State University about the world of RNA chemistry.

From Pittcon 5 May 2023

Crohn’s disease: Symptoms, diagnosis, and treatments

Anyone newly diagnosed with Crohn's disease likely has a lot of questions – and probably some anxiety – about having a chronic ailment for which there's no cure.

4 May 2023

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform."

3 May 2023

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).

2 May 2023

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Small amounts of nanometer-thin metal-organic layers efficiently protect red blood cells during freezing and thawing, as a team of researchers writing in the journal Angewandte Chemie has discovered. The nanolayers, made from metal-organic frameworks based on the metal hafnium, prevent ice crystal formation at very low concentrations. This effective novel cryoprotection mode could be used to develop new and more efficient cryoprotectants for the biosciences.

29 Apr 2023

Researchers develop novel bio-inspired molecules to enhance bone regeneration

People's ability to regenerate bones declines with age and is further decreased by diseases such as osteoporosis.

28 Apr 2023

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

Research discusses recent advances in computer-aided drug discovery, including the use of virtual screening and deep learning methods and their potential to revolutionize the drug discovery process by identifying diverse, potent, and drug-like ligands to protein targets.

28 Apr 2023

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs.

27 Apr 2023

Developing Next-Generation Nanomaterials for Medical Applications

In this interview conducted at Pittcon 2023 in Philadelphia, Pennsylvania, we spoke to Dr. Chad Merkin, Director of the International Institute for Nanotechnology, about his work developing next-generation nanomaterials for medical applications.

From Pittcon 27 Apr 2023

Study uncovers a protein-protein interaction that contributes to Parkinson's disease

In a study published in Nature Communications, a team led by Krembil Brain Institute Senior Scientists, Drs. Lorraine Kalia and Suneil Kalia, and University of Toronto (U of T) Professor, Dr. Philip M. Kim, identified a protein-protein interaction that contributes to Parkinson's disease.

20 Apr 2023

New drug could effectively disarm multidrug-resistant bacteria

A new type of drug could provide a way to treat multidrug-resistant bacteria, according to a study published in Nature Communications.

19 Apr 2023

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Researchers present the crystal structure of an anti-non-structural protein 9 specific nanobody in complex with the SARS-CoV-2 nsp9.

15 Apr 2023

Genomic study reveals Babesia duncani's pathogenicity and virulence

'Tis the season for hiking now that spring has arrived and temperatures are on the upswing. But with hikes come insect bites and on the increase in North America is babesiosis, a malaria-like disease spread especially between May and October by a tick.

13 Apr 2023

MIP Discovery announces drugs of abuse reagent launch

MIP Discovery, a leader in rationally designed detection reagents based on its proprietary nanoMIP technology, in response to the growing synthetic opioid crisis has announced the launch of its first drugs of abuse products which are able to recognize norfentanyl, the main urinary metabolite of fentanyl.

From MIP Discovery 4 Apr 2023

Small Molecules News and Research

Exploring the World of RNA Chemistry

Crohn’s disease: Symptoms, diagnosis, and treatments

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

A dimensional reduction strategy for enhanced cryopreservation of red blood cells

Researchers develop novel bio-inspired molecules to enhance bone regeneration

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

Developing Next-Generation Nanomaterials for Medical Applications

Study uncovers a protein-protein interaction that contributes to Parkinson's disease

New drug could effectively disarm multidrug-resistant bacteria

Study uncovers a novel fold within the SARS-CoV-2 replication co-factor non-structural protein 9

Genomic study reveals Babesia duncani's pathogenicity and virulence

MIP Discovery announces drugs of abuse reagent launch

Oral antiviral CD04872SC shows promise in neutralizing COVID-19 variants, offering hope for broad-spectrum treatment

Lipid Nanoparticles (LNPs) and DNA delivery – unlocking the future of medical research

New insights and emerging disease-modifying drugs for Alzheimer’s disease treatment

Riboswitch may be the key to advance gene therapy, regenerative medicine

New review examines link between HDLC and different types of cancer

Discovery suggests a new way to treat spinal muscular atrophy

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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