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Spectroscopy is the study of the interaction between radiation (electromagnetic radiation, or light, as well as particle radiation) and matter.
Unlocking intrinsically disordered proteins: an interview with Peter Wright

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years. [More]
2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

2D-NMR could be a powerful complementary technique for assessing biosimilarity of protein drugs

A first-ever interlaboratory study of four versions of a therapeutic protein drug—all manufactured from living cells—reports that an established analytical tool akin to magnetic resonance imaging reliably assessed the atomic structures of the biologically similar products, yielding the equivalent of a fingerprint for each. [More]
Study finding could shed light on molecular mechanisms underlying Huntington's disease

Study finding could shed light on molecular mechanisms underlying Huntington's disease

Researchers at the University of Pittsburgh School of Medicine have shown that the core of the protein clumps found in the brains of people with Huntington's disease have a distinctive structure, a finding that could shed light on the molecular mechanisms underlying the neurodegenerative disorder. [More]
Using single-molecule studies to understand cellular processes: an interview with Professor W. E. Moerner

Using single-molecule studies to understand cellular processes: an interview with Professor W. E. Moerner

Single fluorescent molecules provide a local nanometer-sized probe of complex systems. We can measure the motion of the single molecule, use them to achieve imaging on a scale down to 20 nanometers, or we can infer aspects of the behaviour of the object under study by the details of the light that is emitted. [More]
WASF3 protein appears to be solid target for reducing cancer metastasis

WASF3 protein appears to be solid target for reducing cancer metastasis

A protein that is constantly expressed by cancer cells and quiescent in healthy ones appears to be a solid target for reducing cancer's ability to spread, scientists report. [More]
New study shows neurocognitive benefits of stand-height desks in classrooms

New study shows neurocognitive benefits of stand-height desks in classrooms

Do students think best when on their feet? A new study by the Texas A&M Health Science Center School of Public Health indicates they do. [More]
Determining ectopeptidase activity: an interview with Professor Stephen Weber, University of Pittsburgh

Determining ectopeptidase activity: an interview with Professor Stephen Weber, University of Pittsburgh

The scope of the activity of neuropeptides is remarkably broad. For example, neuropeptides are involved in pain control, mood/depression/eating disorders, social and emotional behaviour, body weight, drug abuse, stress, reproduction, motor control, memory, and in maintaining neuronal health when they are stressed. [More]
Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Researchers reveal secondary structure of Lewy bodies in the brain of Parkinson's disease patients

Lewy bodies had been considered to be a key element of pathogenesis for Parkinson's disease. Although structural analysis for Lewy bodies with an electron microscope had been performed, it had no secondary structural information of proteins, which is important for the development of drugs. [More]
Inflammation associated with elevated glutamate in the brain could guide depression treatments

Inflammation associated with elevated glutamate in the brain could guide depression treatments

Psychiatrists investigating depression have been energized in recent years by reports of rapid, successful treatment with drugs that interfere with the brain chemical glutamate, such as the anesthetic ketamine. [More]
Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

Laser-induced breakdown spectroscopy emerges as fast, cost-efficient method for biomass analysis

Laser-induced breakdown spectroscopy (LIBS) is emerging as a fast, cost-efficient method for identifying the total amount and specific compounds that comprise the inorganic component of biomass. Accurate and reliable analysis of these minerals, such as aluminum, calcium, iron, and silicon is essential, as this "ash" can cause problems when converting biomass to hydrocarbon biofuels, as described in a study published in Industrial Biotechnology, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]

Metrohm USA and University of Maryland School of Pharmacy form partnership

Metrohm USA and the University of Maryland School of Pharmacy have recently formed a mutually beneficial partnership. The alliance will bring state-of-the-art analytical instrumentation and software to the School to be used by students and faculty in a variety of disciplines. The presence of Metrohm at the School of Pharmacy will foster collaboration between Metrohm scientists and the renowned research and education leaders at the School. Collaborative work is already under way in the laboratory of Dr. Stephen Hoag, Professor of Pharmaceutical Sciences. [More]
ImpediMed introduces L-Dex system for clinical assessment of lymphedema in U.S.

ImpediMed introduces L-Dex system for clinical assessment of lymphedema in U.S.

ImpediMed Limited, a global provider of medical technology to measure, monitor and manage fluid status in patients, has announced the U.S. commercial launch of its L-Dex system to aid in the clinical assessment of lymphedema. [More]
CMFT adopts ZedScan system to improve cervical cancer care

CMFT adopts ZedScan system to improve cervical cancer care

DP Medical Systems Ltd has secured a deal with Central Manchester University Hospitals NHS Foundation Trust (CMFT) to adopt ZedScan™ as part of its cervical cancer care pathway. [More]
Harvard scientists link specific neurotransmitter in the brain with autistic behavior

Harvard scientists link specific neurotransmitter in the brain with autistic behavior

In a discovery that could offer valuable new insights into understanding, diagnosing and even treating autism, Harvard scientists for the first time have linked a specific neurotransmitter in the brain with autistic behavior. [More]
Can nanostructured microelectrodes be used to analyze biomarkers? An interview with Dr Shana Kelley

Can nanostructured microelectrodes be used to analyze biomarkers? An interview with Dr Shana Kelley

Electrochemical methods are appealing because simple and inexpensive instrumentation can be used to make highly sensitive measurements. However, it has been quite difficult to realize clinically-relevant levels of sensitivity using electrochemistry in highly complex, real-world samples. [More]
New analysis provides insight into the way water and DNA interact

New analysis provides insight into the way water and DNA interact

In a biological system, the ratio of water-to-non-water molecules, known as the hydration level, influences both the arrangement of biomolecules and the strength of the electric interactions that occur between biomolecules, free ions, and functional groups, which are groups of atoms within molecules that strongly influence the molecules' chemical properties. [More]
Neuroscientists find link between neurotransmitter GABA and tactile learning

Neuroscientists find link between neurotransmitter GABA and tactile learning

In an international collaboration with the Johns Hopkins University (Baltimore, MD, USA), neuroscientists at the Ruhr-University Bochum have determined a link between brain levels of the neurotransmitter GABA, the main source of inhibition in the brain, and tactile learning. Using magnetic resonance spectroscopy, they were able to show that success in learning can be predicted by baseline GABA levels. [More]
Study reveals molecular function of protein essential for replication of H5N1 flu virus

Study reveals molecular function of protein essential for replication of H5N1 flu virus

An international collaboration of scientists from the CEA, CNRS, University Joseph Fourier, the EMBL and the ILL has revealed the molecular function of a protein essential for replication of H5N1 influenza virus. [More]
New GASMAS-based technique shows promise for non-invasive sinusitis diagnostics

New GASMAS-based technique shows promise for non-invasive sinusitis diagnostics

A team of scientists from the South China Normal University (Guangzhou, China) and the Lund University (Sweden) led by Sune Svanberg now presents a new approach for a non-intrusive optical technique for human sinus realtime diagnostics that could be developed into a cost-effective, easy-to-use hand-held instrument. [More]
The importance of flexibility in spectrophotometry: an interview with Jessica Geisler

The importance of flexibility in spectrophotometry: an interview with Jessica Geisler

Spectrophotometry quantifies the concentration of a specific substance that is present in a sample by comparing the amount of light that goes into a sample versus the amount of light that comes out of the sample at a specific wavelength. [More]
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