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The term sperm refers to the male reproductive cells. In the types of sexual reproduction known as anisogamy and oogamy, there is a marked difference in the size of the gametes with the smaller one being termed the "male" or sperm cell. The human sperm cell is haploid, so that its 23 chromosomes can join the 23 chromosomes of the female egg to form a diploid cell.
Researchers one step closer to unraveling complex processes crucial to sperm development

Researchers one step closer to unraveling complex processes crucial to sperm development

Researchers are one step closer to unraveling the extraordinarily complex series of processes that leads to an event crucial to human reproduction: the creation of sperm. [More]
CHOPS syndrome sheds light on key biological processes during human development

CHOPS syndrome sheds light on key biological processes during human development

Analyzing a puzzling multisystem disorder in three children, genetic experts have identified a new syndrome, shedding light on key biological processes during human development. The research also provides important information to help caregivers manage the disorder, and may offer clues to eventually treating it. [More]
Einstein researchers find possible clue to why older mothers have babies born with Down syndrome

Einstein researchers find possible clue to why older mothers have babies born with Down syndrome

Researchers at Albert Einstein College of Medicine of Yeshiva University have found a possible clue to why older mothers face a higher risk for having babies born with conditions such as Down syndrome that are characterized by abnormal chromosome numbers. [More]
First comprehensive maps and analyses of human epigenomes revealed

First comprehensive maps and analyses of human epigenomes revealed

Two dozen scientific papers published online simultaneously on Feb. 18, 2015 present the first comprehensive maps and analyses of the epigenomes of a wide array of human cell and tissue types. Epigenomes are patterns of chemical annotations to the genome that determine whether, how, and when genes are activated. [More]
UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

UT Southwestern scientists identify new biomarker that could optimize chemotherapy response

UT Southwestern Medical Center scientists have identified a new biomarker that could help identify patients who are more likely to respond to certain chemotherapies. [More]
Microsurgical technique revolutionizes treatment of infertile men

Microsurgical technique revolutionizes treatment of infertile men

A microsurgical technique credited with revolutionizing treatment of men once thought to be infertile was recently performed at Henry Ford Hospital in Detroit, a first for southeast Michigan. [More]
Study shows that de novo mutations can be detected in human in vitro fertilized embryos using PGD

Study shows that de novo mutations can be detected in human in vitro fertilized embryos using PGD

Reprogenetics, the largest U.S. genetics laboratory specializing in Preimplantation Genetic Diagnosis (PGD), announced today the publication of new clinical data in the March issue of Genome Research demonstrating that de novo single base mutations can be detected in embryos after in vitro fertilization (IVF). [More]
Jefferson, RMA of Philadelphia announce clinical partnership

Jefferson, RMA of Philadelphia announce clinical partnership

Jefferson announced today its clinical partnership with RMA of Philadelphia, merging the expertise of two outstanding groups of reproductive specialists on its Center City campus. [More]
Parents can pass silenced genes to offspring through a specific mechanism

Parents can pass silenced genes to offspring through a specific mechanism

For more than a century, scientists have understood the basics of inheritance: if good genes help parents survive and reproduce, the parents pass those genes along to their offspring. And yet, recent research has shown that reality is much more complex: genes can be switched off, or silenced, in response to the environment or other factors, and sometimes these changes can be passed from one generation to the next. [More]
INRS researchers to use new specialized equipment to study environmental equity, male infertility

INRS researchers to use new specialized equipment to study environmental equity, male infertility

With the acquisition of new specialized equipment, INRS researchers Philippe Apparicio, Géraldine Delbès, and Maritza Jaramillo and their teams will be able to advance knowledge and train highly qualified people in the fields of environmental equity, reproductive toxicology, and the treatment of infections. They received a total of over $1 million from the Quebec government and the John R. Evans Leaders Fund of the Canadian Foundation for Innovation. [More]
Study: ICSI technique no better than conventional IVF

Study: ICSI technique no better than conventional IVF

The use of an assisted reproduction technique known as intracytoplasmic sperm injection (ICSI) doubled between 1996 and 2012, although compared with conventional in vitro fertilization (IVF), use of ICSI was not associated with improved reproductive outcomes, according to a study in the January 20 issue of JAMA. [More]
Scientists image zinc atoms released by fertilized mammalian egg

Scientists image zinc atoms released by fertilized mammalian egg

Sparks literally fly when a sperm and an egg hit it off. The fertilized mammalian egg releases from its surface billions of zinc atoms in "zinc sparks," one wave after another, found a Northwestern University-led interdisciplinary research team that includes experts from the U.S. Department of Energy's Advanced Photon Source at Argonne National Laboratory. [More]
Sensitive toxicity test aims to detect dangerous side effects in pharmaceutical development

Sensitive toxicity test aims to detect dangerous side effects in pharmaceutical development

Because of undetected toxicity problems, about a third of prescription drugs approved in the U.S. are withdrawn from the market or require added warning labels limiting their use. An exceptionally sensitive toxicity test invented at the University of Utah could make it possible to uncover more of these dangerous side effects early in pharmaceutical development so that fewer patients are given unsafe drugs. [More]
Scientists demonstrate technique for editing genome in sperm-producing adult stem cells

Scientists demonstrate technique for editing genome in sperm-producing adult stem cells

Scientists at Indiana University and colleagues at Stanford and the University of Texas have demonstrated a technique for "editing" the genome in sperm-producing adult stem cells, a result with powerful potential for basic research and for gene therapy. [More]
Endocrinologist examines benefits and harms of testosterone therapy

Endocrinologist examines benefits and harms of testosterone therapy

An article in the latest edition of Australian Prescriber looks at the prescribing of testosterone, often used for ‘male menopause’ symptoms such as reduced energy, poor concentration and increased body fat. Over the past decade there has been a steep rise in the amount of testosterone dispensed in Australia and globally. [More]
Finding could upend scientific consensus about when embryonic cells begin separating into cell types

Finding could upend scientific consensus about when embryonic cells begin separating into cell types

Bioengineers at the University of California, San Diego have discovered that mouse embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery that could upend the scientific consensus about when embryonic cells begin differentiating into cell types. [More]
Uterine contractions have positive effect on artificial insemination

Uterine contractions have positive effect on artificial insemination

The negative impact of contractions during in vitro fertilisation is a well-known fact. What was unknown until now was the effect it had on artificial insemination. [More]
Researchers reveal mechanism that determines direction of egg flow in fallopian tubes

Researchers reveal mechanism that determines direction of egg flow in fallopian tubes

Researchers in Japan have revealed the mechanism that determines the direction of the transportation of eggs in the fallopian tube. [More]
Single mutation in beta-catenin gene can lead to infertility

Single mutation in beta-catenin gene can lead to infertility

Scientists from the RIKEN BioResource Center in Tsukuba, Japan, have discovered that a single mutation in the beta-catenin gene, which codes a protein known to be deeply involved in a number of developmental and homeostatic processes, can lead to infertility not through a disruption of the production of egg or sperm cells, but rather by leading to abnormalities in the morphology of the sexual organs, making natural reproduction impossible. [More]
Two major studies newly implicate dozens of genes in autism

Two major studies newly implicate dozens of genes in autism

Two major genetic studies of autism, led in part by UC San Francisco scientists and involving more than 50 laboratories worldwide, have newly implicated dozens of genes in the disorder. The research shows that rare mutations in these genes affect communication networks in the brain and compromise fundamental biological mechanisms that govern whether, when, and how genes are activated overall. [More]