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Statins are drugs used to lower cholesterol. Your body needs some cholesterol to work properly. But if you have too much in your blood, it can stick to the walls of your arteries, narrowing or even blocking them.
Statins could reduce threat of venous thromboembolism, research shows

Statins could reduce threat of venous thromboembolism, research shows

Statins could hold the key to eradicating one of the most preventable causes of hospital deaths after researchers uncovered a new role for the cholesterol-lowering pill. [More]
UIC chemists pinpoint role of cholesterol in cells

UIC chemists pinpoint role of cholesterol in cells

Scientists have long puzzled over cholesterol. It's biologically necessary; it's observably harmful - and nobody knows what it's doing where it's most abundant in cells: in the cell membrane. [More]
TMDU researchers identify metabolic pathway crucial for embryo development

TMDU researchers identify metabolic pathway crucial for embryo development

Much has been revealed about how a single fertilized cell, the egg, can develop into a complete organism simply via repeated cycles of cell division. However, many gaps remain in our understanding of how these dividing cells are directed to arrange themselves appropriately at each stage of embryonic development. [More]
Reducing cocaine use can potentially reverse coronary atherosclerosis

Reducing cocaine use can potentially reverse coronary atherosclerosis

People who use cocaine regularly are at high risk of coronary artery disease. A study in the Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine, reports that stopping or reducing cocaine use can potentially reverse the process of coronary atherosclerosis. The journal is published by Wolters Kluwer. [More]
Fenofibrate drug may reduce risk of cardiovascular events in patients with type 2 diabetes

Fenofibrate drug may reduce risk of cardiovascular events in patients with type 2 diabetes

A new study shows that the drug fenofibrate might reduce the risk of cardiovascular events in patients with type 2 diabetes who have high levels of triglycerides and low levels of "good" cholesterol, despite being treated with statins. [More]
Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

Saint Louis University geriatrician urges older patients to talk to doctors about too many pills

If you're 65 or older and taking more than four medications, resolve to talk to your doctor about doing a New Year's triage to make sure too many pills aren't making you sick, advises Milta Little, D.O., associate professor of geriatrics at Saint Louis University. [More]
Heart attack risk for people with HIV nearly 50% higher than predicted

Heart attack risk for people with HIV nearly 50% higher than predicted

Current methods to predict the risk of heart attack and stroke vastly underestimate the risk in individuals with HIV, which is nearly double that of the general population, reports a new Northwestern Medicine study. [More]
NHS Health Checks may have prevented up to 8,400 heart attacks and strokes, review reveals

NHS Health Checks may have prevented up to 8,400 heart attacks and strokes, review reveals

The NHS Health Check programme in England may have prevented an estimated 4,600 to 8,400 heart attacks, strokes, or death from these causes in its first five years, according to an independent review of the programme led by Queen Mary University of London. [More]
Reducing cholesterol to level of newborn baby lowers cardiovascular disease risk, research finds

Reducing cholesterol to level of newborn baby lowers cardiovascular disease risk, research finds

Reducing our cholesterol levels to those of a new-born baby significantly lowers the risk of cardiovascular disease, according to new research. [More]
Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk

Common anti-cholesterol drugs show promise for reducing Alzheimer's disease risk

Common anti-cholesterol drugs show promise for reducing the risk of Alzheimer's disease, a University of Southern California-led study of Medicare data reveals. [More]
PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

PCSK9 and HMGCR genetic variations that lower bad cholesterol affect risk of cardiovascular events

In a new study published in the December 1, 2016 issue of The New England Journal of Medicine, researchers at Brigham and Women's Hospital, and a collaboration of international researchers, studied variants in the genes encoding HMGCR and PCSK9 that affect cholesterol levels, and found that variants that lowered LDL (or "bad") cholesterol in each gene were associated with nearly identical protective effects on the risk of cardiovascular events per unit reduction in LDL cholesterol. [More]
Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Statins can help prevent first time heart attacks, strokes in adults with cardiovascular risk factors

Cholesterol-lowering drugs help prevent heart attacks and strokes in adults with cardiovascular risk factors such as high cholesterol, high blood pressure, diabetes and smoking, but have not yet had a heart attack or stroke, according to a large-scale analysis of clinical trial data led by the OHSU Pacific Northwest Evidence-Based Practice Center. [More]
USPSTF recommends use of low- to moderate-dose statins for preventing CVD events in adults

USPSTF recommends use of low- to moderate-dose statins for preventing CVD events in adults

The U.S. Preventive Services Task Force has issued a recommendation statement regarding the use of statins for primary prevention of cardiovascular disease in adults. The report appears in the November 15 issue of JAMA. [More]
New guidelines recommend use of antiplatelet therapy and exercise program for treatment of PAD

New guidelines recommend use of antiplatelet therapy and exercise program for treatment of PAD

New guidelines for the treatment of peripheral artery disease (PAD), include recommendations on the use of antiplatelet therapy to reduce the risk of blood clots and statin drugs to lower cholesterol and advise PAD patients to participate in a structured exercise program. [More]
High-intensity statin treatments increase survival rates in patients with cardiovascular disease

High-intensity statin treatments increase survival rates in patients with cardiovascular disease

A large national study has confirmed the value of high-intensity statin treatments for people with cardiovascular disease, according to researchers at the Stanford University School of Medicine. [More]
Risk and reality do not always match up in prostate cancer biopsies, research suggests

Risk and reality do not always match up in prostate cancer biopsies, research suggests

When it comes to prostate cancer biopsies, risk and reality don't always match up, according to research published online today in the Journal of Clinical Oncology. [More]
Small changes in diet can reduce CVD risk by 30%

Small changes in diet can reduce CVD risk by 30%

Exchanging few commercially regular-consumed food items with improved fat quality reduces total and LDL cholesterol. [More]
NCDR provides data to study appropriate use of oral anticoagulant therapy

NCDR provides data to study appropriate use of oral anticoagulant therapy

The American College of Cardiology's National Cardiovascular Data Registry was the source of data for research published throughout 2016, including a study examining if atrial fibrillation patients are being prescribed oral anticoagulants, how appropriate use criteria correlates to angioplasty rates and the variation among racial groups for revascularization procedures. [More]
Study evaluates link between lowering LDL-C and CV risk reduction across statin and nonstatin therapies

Study evaluates link between lowering LDL-C and CV risk reduction across statin and nonstatin therapies

In a study appearing in the September 27 issue of JAMA, Marc S. Sabatine, M.D., M.P.H., of Brigham and Women's Hospital, Harvard Medical School, Boston, and colleagues evaluated the association between lowering low-density lipoprotein cholesterol (LDL-C) and relative cardiovascular risk reduction across different statin and nonstatin therapies. [More]
HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

HIJ-PROPER trial: Intensive cholesterol-lowering regimen in ACS patients shows no better outcomes

Survival and other cardiovascular outcomes were not significantly reduced with intensive treatment using a second-line cholesterol-lowering medication on top of a standard statin, compared to statin treatment alone in patients with acute coronary syndrome (ACS) and dyslipidemia, investigators reported here. [More]
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