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ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

ART trial: Adacolumn shows clinical benefit in refractory ulcerative colitis patients

Data from the 48-week ART trial, presented today at the Digestive Disease Week meeting, showed that remission and response rates were 37.2% and 53.2% respectively at week 12, in patients with moderate-to-severe, steroid-dependent active ulcerative colitis (UC) with insufficient response or intolerance to immunosuppressants and / or biologics when treated with between five and eight sessions with Adacolumn. [More]
Transplanted human stool may offer treatment hope for ulcerative colitis patients

Transplanted human stool may offer treatment hope for ulcerative colitis patients

Patients with ulcerative colitis (UC) may improve their symptoms with a transplantation of healthy stool from donors, according to Australian researchers. The findings were presented by Dr Sudarchan Paramsothy MD, a gastroenterologist from the University of New South Wales, Australia at the Digestive Disease Week conference in San Diego, California between the 21st to 24th May. [More]
Simple tips to reduce pain from sunburn

Simple tips to reduce pain from sunburn

The British Skin Foundation has sun safety tips available to the public on this page and our primary advice is to follow these to avoid sunburn in the first place. However, we realise that sometimes accidents can happen. [More]
Risk factors for hospital readmission after pediatric neurosurgical procedures

Risk factors for hospital readmission after pediatric neurosurgical procedures

Researchers at The University of Alabama at Birmingham have determined specific risk factors associated with hospital readmission following pediatric neurosurgery. [More]
Researchers investigate effects of new steroid treatment on children with ARDS

Researchers investigate effects of new steroid treatment on children with ARDS

Acute Respiratory Distress Syndrome (ARDS) affects hundreds of thousands of people each year, many of them children. Those with this life threatening condition have severely injured and wet lungs, and are treated with mechanical ventilation. [More]
Study highlights importance of routine osteoporosis screening for men

Study highlights importance of routine osteoporosis screening for men

Screening women for osteoporosis is now routine, however, when it comes to men, most are never screened and therefore suffer the consequences of the disease. In the U.S., nearly 1.5 million men over 65 have osteoporosis, and another 3.5 million men are at risk for developing the disease. [More]
Diabetes risk linked to increased dosage, duration and timing of steroids

Diabetes risk linked to increased dosage, duration and timing of steroids

Glucocorticoid (or steroid) therapy, prescribed to around half of patients with rheumatoid arthritis, is a known risk factor for developing diabetes. A study from The University of Manchester has found how the risk of diabetes increases in relation to the dosage, duration and timing of steroids. [More]
Real risk of rebound syndrome following fingolimod cessation for MS

Real risk of rebound syndrome following fingolimod cessation for MS

Rebound syndrome following cessation of fingolimod for multiple sclerosis occurs at a clinically relevant rate, shows research, prompting the need for further study on how best to sequence and discontinue such drugs. [More]
Changes in the brain make people prone to alcoholism

Changes in the brain make people prone to alcoholism

The brain tissue of persons with alcohol dependence shows a variety of changes compared to non-alcoholic control persons. All alcoholics' brains share some characteristics, but some are exclusive to the brain tissue of anxiety-prone type 1 alcoholics or impulsive type 2 alcoholics, according to a recent study from the University of Eastern Finland. [More]
Probiotic supplements may help treat post-menopausal osteoporosis

Probiotic supplements may help treat post-menopausal osteoporosis

Probiotic supplements protected female mice from the loss of bone density that occurs after having their ovaries removed, researchers at Emory University School of Medicine and Georgia State University have shown. [More]
Derivatives of female sex hormones can influence natural melanin production, study suggests

Derivatives of female sex hormones can influence natural melanin production, study suggests

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in skin pigmentation, the reason for the changes has long puzzled physicians. [More]
High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

High doses of commonly-used chemotherapy drug may increase survival rate of ALL patients

With a cure rate approaching 90 percent, acute lymphoblastic leukemia (ALL) - the most common type of childhood cancer - is often hailed as one of the "success stories" of modern cancer treatment. But up to 20 percent of patients with a high risk of relapse are not cured. That could change with the results from a clinical trial co-led by investigators from NYU Langone Medical Center, which shows giving high doses of a commonly-used chemotherapy drug increases the survival rate for these patients. [More]
Hydrocortisone drug can also prevent lung damage in premature babies

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen. [More]
SI-2 molecule can inhibit tumor growth in breast cancer mouse model

SI-2 molecule can inhibit tumor growth in breast cancer mouse model

Cancer cells communicate with their environment through cell molecules that pass on signals to the inside of the cell. The signals help cancer cells multiply and migrate, spreading the disease. [More]
Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Investigators find tacrolimus to be very effective in reducing ocular symptoms of GVHD

Researchers from Massachusetts Eye and Ear/Harvard Medical School have conducted a clinical trial comparing the safety and efficacy of topical tacrolimus, an immunosuppressive therapy, and topical methylprednisolone, a steroid medication, in patients with ocular graft-versus-host-disease (GVHD) -- a complication associated with allogeneic bone marrow transplants in which the transplanted immune system's cells attack certain parts of the recipient's body, including the cornea and ocular surface. [More]
UC Berkeley biologists discover potential target for unisex contraceptives

UC Berkeley biologists discover potential target for unisex contraceptives

UC Berkeley biologists have discovered the switch that triggers the power kick sperm use to penetrate and fertilize a human egg, uncovering a possible source of male infertility but also a potential target for contraceptives that work in both men and women. [More]
Mutated gene GT198 has strong potential in early diagnosis of breast cancer

Mutated gene GT198 has strong potential in early diagnosis of breast cancer

When mutated, a gene known for its ability to repair DNA, appears to instead cause breast cancer, scientists report. [More]
Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Southampton researchers explore ADAM33 gene's association with asthma, airway 'twitchiness'

Researchers at the University of Southampton are to study why some people are more likely to develop asthma. [More]
Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Fatness is clearly linked to cardiovascular disease, but scientists want to find why the unhealthy pair tend to go hand-in-hand and how to break up their relationship. [More]
CWRU researcher to customize tobacco mosaic virus to treat human cancers

CWRU researcher to customize tobacco mosaic virus to treat human cancers

A Case Western Reserve University researcher has been awarded more than $3 million in federal and foundation grants to turn common plant viruses into cancer sleuths and search-and-destroy emissaries. [More]
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