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UIC chemists pinpoint role of cholesterol in cells

UIC chemists pinpoint role of cholesterol in cells

Scientists have long puzzled over cholesterol. It's biologically necessary; it's observably harmful - and nobody knows what it's doing where it's most abundant in cells: in the cell membrane. [More]
Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson's disease. [More]
Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

A naturally-occurring compound has been found to block a molecular process thought to underlie Parkinson's Disease, and to suppress its toxic products, scientists have reported. [More]
Study establishes harmonized reference ranges for total testosterone in men

Study establishes harmonized reference ranges for total testosterone in men

A large study of more than 9,000 men has established harmonized reference ranges for total testosterone in men that when applied to assays that have been appropriately calibrated will effectively enable clinicians to make a correct diagnosis of hypogonadism, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. [More]
Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress of emphysema, a common component of chronic obstructive pulmonary disease (COPD). [More]
Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer. [More]
Strong emotional reactions can trigger adrenaline release that causes goose bumps

Strong emotional reactions can trigger adrenaline release that causes goose bumps

When you find yourself in an eerie place or the beat drops just right during a favorite song, the chills start multiplying. You know the feeling. It is a shiver that seems to come from within and makes your hairs stand on end. [More]
New study suggests potential new approach to combat spread of malaria

New study suggests potential new approach to combat spread of malaria

Disruption of hormone signaling in mosquitoes may reduce their ability to transmit the parasite that causes malaria, according to a new study published in PLOS Pathogens. The findings suggest a potential new approach to combat spread of the disease. [More]
Scientists discover new class of host molecules to transport steroids in the body

Scientists discover new class of host molecules to transport steroids in the body

Synthetic hosts are to transport medical substances and hormones into the body and to release them at specific points. [More]
Controversial hormone could fight against recurring breast cancers

Controversial hormone could fight against recurring breast cancers

An international team of researchers involving the University of Adelaide is tackling the controversy over what some scientists consider to be a "harmful" hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments. [More]
Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

Endometrial microbiota play vital role in determining reproductive outcome in women undergoing IVF

Endometrial microbiota (bacteria in the uterine cavity) play an important role in determining whether women are able to get pregnant via in vitro fertilization (IVF), according to a new study published in the American Journal of Obstetrics and Gynecology. [More]
Study reveals why air pollutants cause some people to be at risk for atopic dermatitis

Study reveals why air pollutants cause some people to be at risk for atopic dermatitis

Tohoku University Graduate School of Medicine and Tohoku Medical Megabank Organization are pleased to announce the published results of a study into why air pollutants cause some people to be more susceptible to atopic dermatitis, a kind of skin inflammation. [More]
TUM scientists explore link between gastrointestinal microbiota and dietary fats

TUM scientists explore link between gastrointestinal microbiota and dietary fats

Gut bacteria play a little-understood role in the body’s energy balance, which is influenced by diet. However, the crucial nutritional components are unknown. A team at the Technical University of Munich was able to demonstrate for the very first time that mice without gastrointestinal microbiota grow obese when fed with dietary fat from plant sources, but not from animal sources. [More]
Men lack knowledge about risk factors contributing to male infertility, study finds

Men lack knowledge about risk factors contributing to male infertility, study finds

The first large-scale study of its kind has revealed that Canadian men generally lack knowledge about the risk factors contributing to male infertility. [More]
Results of high-impact clinical trials could improve kidney-related medical care

Results of high-impact clinical trials could improve kidney-related medical care

The results of numerous high-impact clinical trials that could affect kidney-related medical care will be presented at ASN Kidney Week 2016, November 15-20 at McCormick Place in Chicago, IL. [More]
Study: Fungal asthma in UK greatly exceeds prior estimates

Study: Fungal asthma in UK greatly exceeds prior estimates

Experts are warning of a significant increase in the number of people in the UK who are living with invasive and serious fungal diseases that affect the lungs, bloodstream and brain and can sometimes lead to death. [More]
Exposure to licorice compound disrupts steroid sex hormone production in ovary

Exposure to licorice compound disrupts steroid sex hormone production in ovary

A study of mouse reproductive tissues finds that exposure to isoliquiritigenin, a compound found in licorice, disrupts steroid sex hormone production in the ovary, researchers report. [More]
Study elucidates why women have higher risk of developing Alzheimer's disease than men

Study elucidates why women have higher risk of developing Alzheimer's disease than men

Women have a two-fold higher risk of developing Alzheimer's disease than men, yet strikingly little is known about how changes in brain function promote this difference -- and how early in midlife those changes can be detected. [More]
Oral vitamin D supplement could reduce risk of severe asthma attacks

Oral vitamin D supplement could reduce risk of severe asthma attacks

A recent Cochrane Review has found evidence from randomised trials, that taking an oral vitamin D supplement in addition to standard asthma medication is likely to reduce severe asthma attacks. [More]
CHEST, ATS release new guidelines for discontinuing mechanical ventilation in critically ill adults

CHEST, ATS release new guidelines for discontinuing mechanical ventilation in critically ill adults

The American College of Chest Physicians and the American Thoracic Society have published new guidelines for discontinuing mechanical ventilation in critically ill adults. [More]
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