Stroke News and Research

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A stroke is a medical emergency. Strokes happen when blood flow to your brain stops. Within minutes, brain cells begin to die. There are two kinds of stroke. The more common kind, called ischemic stroke, is caused by a blood clot that blocks or plugs a blood vessel in the brain. The other kind, called hemorrhagic stroke, is caused by a blood vessel that breaks and bleeds into the brain. "Mini-strokes" or transient ischemic attacks (TIAs), occur when the blood supply to the brain is briefly interrupted.

Researchers demonstrate connection between circadian rhythm, platelet function and cardiovascular risk

Researchers at Brigham and Women's Hospital (BWH) have demonstrated that the circadian system, the body's internal clock, regulates human platelet function and causes a peak in platelet activation corresponding to the known morning peak in adverse cardiovascular events. These findings are published in PLoS ONE on September 8, 2011.

9 Sep 2011

Autophagy also mobilizes and exports cholesterol from cells

Researchers at the University of Ottawa Heart Institute (UOHI) have discovered that an ancient pathway called autophagy also mobilizes and exports cholesterol from cells.

9 Sep 2011

Feds stop brain stent stroke study after failures

A promising but expensive device to prop open blocked arteries in the brain in the hope of preventing disabling or fatal strokes failed in a rigorous study, researchers reported on Wednesday. Those who got the device actually had so many more strokes than those assigned to control risk factors, like blood pressure, cholesterol and diabetes, that the study was abruptly terminated.

9 Sep 2011

Study examines alcohol use in relation to successful ageing among women

Among 13,894 women in the Nurses' Health Study, investigators prospectively examined alcohol use assessed at midlife in relation to "successful ageing," which was defined as survival to age 70 years, not having a major chronic disease, and having no major cognitive impairment, physical impairment, or mental health problems.

9 Sep 2011

Cardiovascular and Renal Drugs Advisory Committee recommends FDA approval of J&JPRD's rivaroxaban

Johnson & Johnson Pharmaceutical Research and Development, L.L.C. (J&JPRD) announced today that the U.S. Food and Drug Administration's (FDA) Cardiovascular and Renal Drugs Advisory Committee recommended approval of rivaroxaban, a novel, once-daily, oral anticoagulant, for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

9 Sep 2011

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

The Juvenile Diabetes Research Foundation (JDRF), the worldwide leader for research to cure, treat, and prevent type 1 diabetes, and InnoCentive, Inc., the pioneer in open innovation and crowdsourcing, today announced a $100,000 Challenge calling for innovative ways to approach the discovery and development of a glucose-responsive insulin drug as a means to treat insulin-dependent diabetes.

9 Sep 2011

UOHI team identifies that autophagy also mobilizes and exports cholesterol from cells

Researchers at the University of Ottawa Heart Institute (UOHI) have discovered that an ancient pathway called autophagy also mobilizes and exports cholesterol from cells.

9 Sep 2011

Stents for blocked brain arteries may not be as successful in prolonging survival as believed: Study

A study out this Wednesday says that insertion of an artery-opening device called a stent into the brain to improve blood flow to prevent a second stroke may do more harm than managing high-risk patients with drugs and lifestyle changes. Blocked brain arteries caused by the build-up of fatty deposits called plaque account for more than 50,000 of the 795,000 strokes occurring in the United States each year. Stroke is the fourth-leading cause of death and a leading cause of disability in the United States.

8 Sep 2011

First Edition: September 8, 2011

In today's headlines, reports from last night's GOP presidential debate, as well as explorations of what the future might hold for the 'Super Committee' and news developments related to physician payment issues.

8 Sep 2011

Aggressive medical management better than stenting for prevention of recurrent stroke

Patients at a high risk for a second stroke who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to the medical treatment, a large nationwide clinical trial has shown. The investigators published the results in today's online first edition of the New England Journal of Medicine.

8 Sep 2011

Enrollment complete in Concentric Medical's Stentriever trial for acute ischemic stroke

Concentric Medical, Inc., a global leader in acute ischemic stroke intervention, today announced completion of enrollment of the TREVO Study.

8 Sep 2011

Aggressive medical treatment without stenting better for high-risk stroke patients

An article appearing in the Sept. 7 New England Journal of Medicine, reporting on National Institutes of Health research on brain stents, says aggressive medical treatment without stenting is better for high-risk stroke patients.

8 Sep 2011

Intensive medical treatment more effective in preventing second stroke than stenting

People who received intensive medical treatment following a first stroke had fewer second episodes and were less likely to die than people who received brain stents in addition to medical treatment, according to a new report in the New England Journal of Medicine, to be published online Sept. 7.

8 Sep 2011

Hospitals: HHS inspector general counsel backs telemedicine plan for stroke care program

Hospital issues making headlines include a telemedicine plan, the unreliability of some children's hospital rankings and how long hospital wait times can be deadly.

8 Sep 2011

Daily moderate drinking may decrease atherosclerosis

For the first time, new research shows that patterns of alcohol consumption - a drink or two every night, or several cocktails on Friday and Saturday nights only - may be more important in determining alcohol's influence on heart health than the total amount consumed.

8 Sep 2011

Exercise, intervention may help individuals with peripheral arterial disease

Peripheral arterial disease, or PAD, is a common condition affecting 12-20 percent of Americans age 65 and older that may be a signal of future heart attack and stroke-and many with the disease may be unaware they have it, says the Society of Interventional Radiology.

8 Sep 2011

New surprising discovery on division of mitochondria within cells

A surprising new discovery by the University of Colorado Boulder and the University of California, Davis regarding the division of tiny "power plants" within cells known as mitochondria has implications for better understanding a wide variety of human diseases and conditions due to mitochondrial defects.

8 Sep 2011

Simple pain relievers a better alternative to antipsychotic medications for dementia patients

Many dementia patients are being treated with antipsychotic medications, but a new study shows that simple pain relievers may be a better alternative.

8 Sep 2011

Researchers rethink fenretinide for prevention of oral cancer

Scientists on the cutting edge of biomedical research know that research is a process - a combination of successes and failures that inform the next step forward. However, for some researchers at The Ohio State University progress means taking a step back. Supported by the Ohio State University Center for Clinical and Translational Science (CCTS), these scientists are using failed and forgotten research to uncover future treatments for major health conditions as diverse as oral cancer and stroke.

7 Sep 2011

Cheap medicines could prevent huge number of deaths from heart attacks, strokes

A major new international study involving researchers from the Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital has revealed that aspirin, statins, beta blockers and ACE inhibitors are prescribed far too infrequently. They are cheap, preventive medicines that could prevent a huge number of deaths from heart attacks and strokes.

7 Sep 2011

Stroke News and Research

Further Reading

Researchers demonstrate connection between circadian rhythm, platelet function and cardiovascular risk

Autophagy also mobilizes and exports cholesterol from cells

Feds stop brain stent stroke study after failures

Study examines alcohol use in relation to successful ageing among women

Cardiovascular and Renal Drugs Advisory Committee recommends FDA approval of J&JPRD's rivaroxaban

InnoCentive, JDRF announce $100,000 Challenge to uncover solutions for insulin-dependent diabetes

UOHI team identifies that autophagy also mobilizes and exports cholesterol from cells

Stents for blocked brain arteries may not be as successful in prolonging survival as believed: Study

First Edition: September 8, 2011

Aggressive medical management better than stenting for prevention of recurrent stroke

Enrollment complete in Concentric Medical's Stentriever trial for acute ischemic stroke

Aggressive medical treatment without stenting better for high-risk stroke patients

Intensive medical treatment more effective in preventing second stroke than stenting

Hospitals: HHS inspector general counsel backs telemedicine plan for stroke care program

Daily moderate drinking may decrease atherosclerosis

Exercise, intervention may help individuals with peripheral arterial disease

New surprising discovery on division of mitochondria within cells

Simple pain relievers a better alternative to antipsychotic medications for dementia patients

Researchers rethink fenretinide for prevention of oral cancer

Cheap medicines could prevent huge number of deaths from heart attacks, strokes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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