Tamoxifen News and Research RSS Feed - Tamoxifen News and Research

Tamoxifen is a drug used to treat certain types of breast cancer in women and men. It is also used to prevent breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast) and in women who are at a high risk of developing breast cancer. Tamoxifen is also being studied in the treatment of other types of cancer. It blocks the effects of the hormone estrogen in the breast. Tamoxifen is a type of antiestrogen. Also called tamoxifen citrate.
TSRI researchers develop new approach to find how environmental estrogens impact public health

TSRI researchers develop new approach to find how environmental estrogens impact public health

Breast cancer researchers from the Florida campus of The Scripps Research Institute have developed a novel approach for identifying how chemicals in the environment—called environmental estrogens—can produce infertility, abnormal reproductive development, including “precocious puberty,” and promote breast cancer. [More]
TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

TSRI scientists develop new approach for understanding diverse effects of endocrine-disruptors

Breast cancer researchers from the Florida campus of The Scripps Research Institute (TSRI) have developed a novel approach for identifying how chemicals in the environment--called environmental estrogens--can produce infertility, abnormal reproductive development, including "precocious puberty," and promote breast cancer. [More]
Aromatase inhibitors show advantages over tamoxifen in early-stage breast cancer

Aromatase inhibitors show advantages over tamoxifen in early-stage breast cancer

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated whether and what advantages drugs from the drug class of aromatase inhibitors offer compared with other breast cancer treatments or with each other. [More]
Research findings could offer novel approach for cancer prevention in women with BRCA1 mutations

Research findings could offer novel approach for cancer prevention in women with BRCA1 mutations

Women with inherited mutations in the BRCA1 or BRCA2 genes are at substantially higher risk of breast cancer. For these women, effective prevention strategies are their best hope to reduce their breast cancer risk. [More]
Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Multifunctional RNA nanoparticles could overcome treatment resistance in breast cancer, study shows

Researchers at the University of Cincinnati College of Medicine have been able to generate multifunctional RNA nanoparticles that could overcome treatment resistance in breast cancer, potentially making existing treatments more effective in these patients. [More]
One fifth of breast cancer patients do not complete their prescribed endocrine therapy

One fifth of breast cancer patients do not complete their prescribed endocrine therapy

Around 20% of breast cancer patients do not complete prescribed endocrine therapy, researchers report at the ESMO Asia 2016 Congress in Singapore.1 The study in over 5,500 women found that younger patients and those who had taken hormone replacement therapy (HRT) were less likely to adhere to their medicine. [More]
Symptoms from other causes may be mistaken for side effects of breast cancer drug

Symptoms from other causes may be mistaken for side effects of breast cancer drug

Women taking tamoxifen to prevent breast cancer were less likely to continue taking the drug if they suffered nausea and vomiting, according to new data presented at the San Antonio Breast Cancer Symposium today (Friday). [More]
Controversial hormone could fight against recurring breast cancers

Controversial hormone could fight against recurring breast cancers

An international team of researchers involving the University of Adelaide is tackling the controversy over what some scientists consider to be a "harmful" hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments. [More]
Kratom may be safer and less addictive than current treatments for pain, research suggests

Kratom may be safer and less addictive than current treatments for pain, research suggests

A delayed U.S. Drug Enforcement Administration ban on kratom would stifle scientific understanding of the herb's active chemical components and documented pharmacologic properties if implemented, according to a special report published today in The Journal of the American Osteopathic Association. [More]
Electro-acupuncture may be effective in treating sleep disturbances in women with breast cancer

Electro-acupuncture may be effective in treating sleep disturbances in women with breast cancer

It's somewhat of a little-known adverse effect of having breast cancer, but studies suggest that approximately 30% to 40% of women with breast cancer report persistent hot flashes. Nocturnal hot flashes are among the most problematic because they can contribute to poor sleep. [More]
TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem. [More]
Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Building on earlier clinical trials, UCLA researchers have confirmed that the "breakthrough" drug palbociclib when used in combination with the traditional hormonal therapy letrozole delays progression of advanced breast cancer significantly and without the harsh side effects seen in some women prescribed letrozole alone. [More]
High out-of-pocket costs, rather than race/ethnicity, may impact adjuvant endocrine therapy adherence

High out-of-pocket costs, rather than race/ethnicity, may impact adjuvant endocrine therapy adherence

High out-of-pocket costs, rather than race or ethnicity, are responsible for disparities associated with adherence to adjuvant endocrine therapy, according to a new study from researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health. [More]
Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found, in animal models of human breast cancer, that inhibiting a single protein restores sensitivity to tamoxifen, a commonly used drug for treatment of some breast cancers. [More]
Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

Breast cancer is the most frequently diagnosed cancer among women, with estrogen-receptor-positive (ER+) being the most common type. [More]
Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

A supplemental "boost" of radiation improves local control and provides an incremental benefit in decreasing breast cancer recurrence for patients with Ductal Carcinoma In Situ (DCIS) who receive whole breast radiation therapy radiation (WBRT) following lumpectomy, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology. [More]
Genetic testing of mtDNA may reveal unknown ancestry that influences risk for breast cancer

Genetic testing of mtDNA may reveal unknown ancestry that influences risk for breast cancer

Genetic testing of mitochondrial DNA could reveal otherwise unknown ancestry that can influence a person's risk for certain types of breast cancer, a new study finds. [More]
Study may help reassure women who fear endometrial side effects of breast cancer drug

Study may help reassure women who fear endometrial side effects of breast cancer drug

A study led by Loyola Medicine researchers may help reassure patients who worry the breast cancer drug tamoxifen could increase their risk of uterine cancer. [More]
Study identifies new gene that suppresses breast cancer in mice

Study identifies new gene that suppresses breast cancer in mice

In recent years, the incidence of breast cancer has been increasing worldwide, and breast cancer is becoming a serious object of public concern. [More]
Novel DNA-altering method could lead to more treatment options for diseases

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods. [More]
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