Tamoxifen News and Research

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Tamoxifen is a drug used to treat certain types of breast cancer in women and men. It is also used to prevent breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast) and in women who are at a high risk of developing breast cancer. Tamoxifen is also being studied in the treatment of other types of cancer. It blocks the effects of the hormone estrogen in the breast. Tamoxifen is a type of antiestrogen. Also called tamoxifen citrate.

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

A team of clinician-scientists and scientists from the University of Nottingham (Malaysia campus), National Cancer Centre Singapore (NCCS), Cancer Research Malaysia, Nanyang Technological University, Singapore (NTU Singapore), University of Malaya, University of Cambridge, A*STAR's Genome Institute of Singapore (GIS) and other institutions, have conducted the largest study done to date of BRCA1 and BRCA2 (BReast CAncer Gene 1 and 2) carriers in an Asian population and refined breast and ovarian cancer risk estimates for this population.

26 Apr 2024

Exploring the link between prenatal nutrition and congenital craniofacial malformations

The complex development of craniofacial skeletal structures and improve treatments for congenital craniofacial malformations.

27 Mar 2024

Piggybacking the glucose sensor technology to build universal drug monitoring system

Rice University synthetic biologists have found a way to piggyback on the glucose monitoring technology used in automated insulin dosing systems and make it universally applicable for the monitoring and dosing of virtually any drug.

15 Mar 2024

Study suggests iron accumulation plays a central role in senescence and fibrosis

Researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis.

18 Dec 2023

Key role of ion and water influx in T cell migration uncovered

Research reveals that T cell migration relies on ion and water influx for actin polymerization and movement, with the WNK1 kinase playing a critical role in regulating these processes, offering new insights into adaptive immunity.

10 Dec 2023

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Study examines the efficacy of anastrozole in preventing breast cancer in postmenopausal women at high risk, focusing on the role of baseline estradiol levels and their impact on treatment outcomes.

7 Dec 2023

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

Researchers report that osteoarthritis is caused by the loss of Gremlin 1 (Grem1)-lineage chondrogenic progenitor cells.

3 Nov 2023

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Researchers discuss the history of endocrine therapies, highlights their adverse metabolic effects, and emphasizes the need for better biomarkers of diabetes.

5 Oct 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Vibrant green leaves sprout from tall fragrant plants sitting neatly in two rows of terracotta pots in Valerie Sponsel's UTSA biology laboratory.

8 Sep 2023

Study finds ways to improve medication adherence in breast cancer survivors

For roughly 80% of breast cancer survivors, treatment doesn't end with surgery, radiation and chemotherapy. Instead, for the next five to 10 years, doctors recommend that they take medication to block sex hormones, which can fuel tumor growth and spark recurrence.

1 Sep 2023

Less is more: Radiotherapy omission deemed safe for certain breast cancer patients

The risk of breast cancer recurrence after breast-conserving surgery.

22 Aug 2023

Anti-estrogenic therapies can suppress growth of ER-negative cancers

Anti-estrogenic therapies can suppress the growth of cancer that does not express estrogen receptors; when combined with immune checkpoint inhibitor therapies, they halt tumor progression in mice models.

21 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

Breast Cancer Now-funded research aims to improve quality of care for black women with breast cancer

Researchers are investigating how to improve the quality of care for black women with breast cancer and reduce health inequalities, thanks to funding from Breast Cancer Now.

2 Aug 2023

Study provides new insights into the intricate cellular processes driving heterotopic ossification

In a new study published on 21 July 2023 by the journal Bone Research, a team of researchers from Johns Hopkins University, using a combination of lineage tracing and single-cell RNA sequencing (scRNA-seq), delved into the contribution of synovial/tendon sheath progenitor cells to heterotopic bone formation.

1 Aug 2023

Tamoxifen News and Research

Further Reading

Largest study of BRCA1 and BRCA2 carriers refines cancer risk estimates in Asian population

Exploring the link between prenatal nutrition and congenital craniofacial malformations

Piggybacking the glucose sensor technology to build universal drug monitoring system

Study suggests iron accumulation plays a central role in senescence and fibrosis

Key role of ion and water influx in T cell migration uncovered

Anastrozole efficacy in breast cancer prevention for high-risk women linked to estrogen levels

Scientists identify progenitor cells that could revolutionize osteoarthritis treatment

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Study finds ways to improve medication adherence in breast cancer survivors

Less is more: Radiotherapy omission deemed safe for certain breast cancer patients

Anti-estrogenic therapies can suppress growth of ER-negative cancers

The impact of epigenetic features on breast cancer treatment and outcomes

Breast Cancer Now-funded research aims to improve quality of care for black women with breast cancer

Study provides new insights into the intricate cellular processes driving heterotopic ossification

Study reveals molecular mechanisms of H. pylori-induced gastric carcinogenesis

Mark Cuban's Cost Plus Drug Company projects huge savings over Medicare for generic cancer medications

A review of the risk factors associated with cancer evolution

Researchers shine new light on a potential target for the treatment of diabetic nephropathy

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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