Tamoxifen News and Research RSS Feed - Tamoxifen News and Research

Tamoxifen is a drug used to treat certain types of breast cancer in women and men. It is also used to prevent breast cancer in women who have had ductal carcinoma in situ (abnormal cells in the ducts of the breast) and in women who are at a high risk of developing breast cancer. Tamoxifen is also being studied in the treatment of other types of cancer. It blocks the effects of the hormone estrogen in the breast. Tamoxifen is a type of antiestrogen. Also called tamoxifen citrate.
Symptoms from other causes may be mistaken for side effects of breast cancer drug

Symptoms from other causes may be mistaken for side effects of breast cancer drug

Women taking tamoxifen to prevent breast cancer were less likely to continue taking the drug if they suffered nausea and vomiting, according to new data presented at the San Antonio Breast Cancer Symposium today (Friday). [More]
Controversial hormone could fight against recurring breast cancers

Controversial hormone could fight against recurring breast cancers

An international team of researchers involving the University of Adelaide is tackling the controversy over what some scientists consider to be a "harmful" hormone, arguing that it could be a game changer in the fight against recurring breast cancers that are resistant to standard treatments. [More]
Kratom may be safer and less addictive than current treatments for pain, research suggests

Kratom may be safer and less addictive than current treatments for pain, research suggests

A delayed U.S. Drug Enforcement Administration ban on kratom would stifle scientific understanding of the herb's active chemical components and documented pharmacologic properties if implemented, according to a special report published today in The Journal of the American Osteopathic Association. [More]
Electro-acupuncture may be effective in treating sleep disturbances in women with breast cancer

Electro-acupuncture may be effective in treating sleep disturbances in women with breast cancer

It's somewhat of a little-known adverse effect of having breast cancer, but studies suggest that approximately 30% to 40% of women with breast cancer report persistent hot flashes. Nocturnal hot flashes are among the most problematic because they can contribute to poor sleep. [More]
TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

TSRI scientists offer novel structure-based drug design strategy for better breast cancer treatment

While there have been advances in the treatment of hormone-driven breast cancer, resistance to these therapies remains a significant problem. [More]
Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Drug combination therapy delays progression of advanced breast cancer without side effects, study shows

Building on earlier clinical trials, UCLA researchers have confirmed that the "breakthrough" drug palbociclib when used in combination with the traditional hormonal therapy letrozole delays progression of advanced breast cancer significantly and without the harsh side effects seen in some women prescribed letrozole alone. [More]
High out-of-pocket costs, rather than race/ethnicity, may impact adjuvant endocrine therapy adherence

High out-of-pocket costs, rather than race/ethnicity, may impact adjuvant endocrine therapy adherence

High out-of-pocket costs, rather than race or ethnicity, are responsible for disparities associated with adherence to adjuvant endocrine therapy, according to a new study from researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health. [More]
Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

Inhibiting single protein could help restore sensitivity to common treatment for breast cancer

A team of investigators led by researchers at Georgetown Lombardi Comprehensive Cancer Center has found, in animal models of human breast cancer, that inhibiting a single protein restores sensitivity to tamoxifen, a commonly used drug for treatment of some breast cancers. [More]
Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

Breast cancer is the most frequently diagnosed cancer among women, with estrogen-receptor-positive (ER+) being the most common type. [More]
Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

Radiation boost provides added benefit to DCIS patients following breast-conserving surgery and WBRT

A supplemental "boost" of radiation improves local control and provides an incremental benefit in decreasing breast cancer recurrence for patients with Ductal Carcinoma In Situ (DCIS) who receive whole breast radiation therapy radiation (WBRT) following lumpectomy, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology. [More]
Genetic testing of mtDNA may reveal unknown ancestry that influences risk for breast cancer

Genetic testing of mtDNA may reveal unknown ancestry that influences risk for breast cancer

Genetic testing of mitochondrial DNA could reveal otherwise unknown ancestry that can influence a person's risk for certain types of breast cancer, a new study finds. [More]
Study may help reassure women who fear endometrial side effects of breast cancer drug

Study may help reassure women who fear endometrial side effects of breast cancer drug

A study led by Loyola Medicine researchers may help reassure patients who worry the breast cancer drug tamoxifen could increase their risk of uterine cancer. [More]
Study identifies new gene that suppresses breast cancer in mice

Study identifies new gene that suppresses breast cancer in mice

In recent years, the incidence of breast cancer has been increasing worldwide, and breast cancer is becoming a serious object of public concern. [More]
Novel DNA-altering method could lead to more treatment options for diseases

Novel DNA-altering method could lead to more treatment options for diseases

Researchers in Singapore have developed a new protein that can alter DNA in living cells with much higher precision than current methods. [More]
Researchers unlock genetic code that disrupts response to breast cancer therapy

Researchers unlock genetic code that disrupts response to breast cancer therapy

Scientists may have unlocked the genetic code that determines why many patients with estrogen receptor-positive breast cancer fail to respond to the widely used drug tamoxifen. [More]
Study reveals needle biopsy hormone receptor testing for DCIS wastes millions

Study reveals needle biopsy hormone receptor testing for DCIS wastes millions

For patients with the most common type of noninvasive breast cancer, routine testing for estrogen and progesterone receptors in tissue taken at the first "needle" biopsy is both unnecessary and wasteful, according to results of a study led by Johns Hopkins pathologists. [More]
ASTRO honors Ms. Keresztes with 2016 Survivor Circle Award

ASTRO honors Ms. Keresztes with 2016 Survivor Circle Award

The American Society for Radiation Oncology has chosen Theresa A. Keresztes, a resident of Wellesley, Massachusetts, to receive the 2016 Survivor Circle Award. [More]
Neoadjuvant endocrine therapy 'a reasonable option' for ER-positive breast cancer

Neoadjuvant endocrine therapy 'a reasonable option' for ER-positive breast cancer

Endocrine therapy should be reconsidered as a potential option in the neoadjuvant setting for localised oestrogen receptor-positive breast cancer, say the authors of a meta-analysis. [More]
Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

Researchers tune into previously unknown cross talk between estrogen and progesterone receptors

One of the first clues pathologists look for in tissue from a newly diagnosed breast cancer patient is the estrogen receptor, a nuclear protein that converts hormonal messages in the bloodstream into instructions for the cell about how to behave [More]
Pretreatment smoking linked to poor prognosis in AI-treated patients

Pretreatment smoking linked to poor prognosis in AI-treated patients

Among older aromatase inhibitor (AI)-treated patients with breast cancer, current smokers at treatment initiation have an increased risk of breast cancer events and distant metastases, say Swedish researchers. [More]
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