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Tau proteins are microtubule-associated proteins found in neurons in the brain.

Review of R&D and novel therapeutic challenges in neurological disorders

20. November 2009 04:39
Research and Markets (http://www.researchandmarkets.com/research/fae4d4/neurological_disea) has announced the addition of Decision Resources, Inc.'s new report "Neurological Disease: Early-Stage R&D and Dealmaking" to their offering. [More]

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Study: Mouse gene uncovers new strategy for treating Alzheimer's disease

12. November 2009 01:32
A new study reveals that a previously undiscovered mouse gene reduces the two major pathological perturbations commonly associated with Alzheimer's disease (AD). The research, published by Cell Press in the November 12 issue of the journal Neuron, finds that the novel gene interacts with a key cellular enzyme previously linked with AD pathology, thereby uncovering a new strategy for treating this devastating disorder. [More]

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Researchers identify mouse gene that reduces the accumulation Alzheimer's plaques and tangles

12. November 2009 01:21
Investigators at Burnham Institute for Medical Research (Burnham) and colleagues have identified a novel mouse gene (Rps23r1) that reduces the accumulation of two toxic proteins that are major players in Alzheimer's disease: amyloid beta and tau. The amyloid and tau lowering functions of this gene were demonstrated in both human and mouse cells. [More]

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Aethlon Medical begins collaborative biomarker program to study neurodegenerative disease

3. November 2009 23:35
Aethlon Medical, Inc. (OTC Bulletin Board: AEMD) announced today that it has initiated a collaborative biomarker discovery program with the Center for the Study of Traumatic Encephalopathy (CSTE) at Boston University School of Medicine and the Sports Legacy Institute (SLI). [More]

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Effects of head injuries on players in the NFL: House Judiciary Committee's call to experts

29. October 2009 05:05
The House Judiciary Committee today called upon national experts and stakeholders in the fields of science and sport to better understand the effects of head injuries on players in the National Football League (NFL). Nationally recognized sports physician and neurosurgeon, Julian E. Bailes, M.D. was called to provide expert testimony based on decades of research detailing how repetitive head trauma on the field leads to long-term neurological damage among athletes. [More]

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Long-term effects of statin therapy could lead to transient or permanent cognitive impairment

29. October 2009 04:50
Besides their tremendous value in treating high cholesterol and lowering the risk of heart disease, statins have also been reported to potentially lower the risks of other diseases, such as dementia. However, a study in the October Journal of Lipid Research finds that similar statin drugs can have profoundly different effects on brain cells -both beneficial and detrimental. [More]

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New class of molecules capable of blocking formation of tau protein fibrils

11. August 2009 02:12
A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to Alzheimer’s disease pathology has been discovered by researchers at the University of Pennsylvania School of Medicine. By assaying close to 300,000 compounds, they have identified drug-like inhibitors of AD tau protein clumping, as reported in the journal Biochemistry. [More]

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Brain imaging (MRI/PET) bring us closer to earlier detection of Alzheimer's

14. July 2009 19:11
Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported today at the Alzheimer's Association 2009 International Conference on Alzheimer's Disease (ICAD 2009) in Vienna. [More]

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Scientists pinpoint molecular cause of Alzheimer's disease

22. May 2009 18:15
A discovery made by researchers at McGill University and the affiliated Lady Davis Research Institute for Medical Research at Montreal's Jewish General Hospital offers new hope for the early diagnosis and treatment of Alzheimer's disease. [More]

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Alzheimer's mechanism suggests combination therapy needed

17. March 2009 21:50
Researchers at the University of Illinois at Chicago College of Medicine have discovered a mode of action for mysterious but diagnostic protein snarls found in the brains of Alzheimer's patients that suggests a one-two punch of therapy may be needed to combat the neurodegenerative disease. [More]

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A biomarker test to diagnose or rule out Alzheimer's disease

16. March 2009 22:04
A test capable of confirming or ruling out Alzheimer's disease has been validated and standardized by researchers at the University of Pennsylvania School of Medicine. [More]

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Anesthesia or hypothermia: Warning for Alzheimer's patients

11. March 2009 22:50
Everyone knows that its important to keep a cool head, but a new study published online in The FASEB Journal shows that for Alzheimer's patients, a cool head may make the disease worse. [More]

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Blood test predicts chance of frontal lobe dementia

8. March 2009 21:36
Frontal lobe dementia (Frontotemporal Dementia, FTD) strikes people at an earlier age. After Alzheimer's disease, FTD is the form of dementia that occurs most frequently in patients younger than 65. [More]

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Forgotten and lost -- when proteins 'shut down' our brain

18. February 2009 11:49
Which modules of the tau protein, in neurons of Alzheimer disease patients, may act in a destructive manner were investigated by researchers from the Max Planck Institute for Biophysical Chemistry (Göttingen) and the Max Planck Unit for Structural Molecular Biology (Hamburg) with the help of Nuclear Magnetic Resonance Spectroscopy ( PLoS Biology , February 17, 2009). [More]

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Tau protein expression predicts breast cancer survival in an unexpected way

14. December 2008 21:18
Expression of the microtubule-binding protein Tau is not a reliable means of selecting breast cancer patients for adjuvant paclitaxel chemotherapy, according to research led by The University of Texas M. D. Anderson Cancer Center. [More]

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