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Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Researchers use CRISPR-based genetic screening to identify three promising HIV treatment targets

Investigators from Whitehead Institute, the Ragon Institute of MGH, MIT and Harvard and the Broad Institute of MIT and Harvard have used CRISPR-Cas9 gene-editing technology to identify three promising new targets for treatment of HIV infection. [More]
Replacing missing gut bacteria could help treat children with rare autoimmune disease

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Defects in the body's regulatory T cells (T reg cells) cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers from The University of Texas Health Science Center at Houston have discovered. [More]
Novel approach shows promise for treating co-occurring PTSD and SUD

Novel approach shows promise for treating co-occurring PTSD and SUD

N-acetylcysteine, when combined with group cognitive behavioral therapy, reduced symptoms of posttraumatic stress disorder (PTSD), cravings, and depression significantly more than CBT alone in veterans with co-occurring PTSD and substance use disorder, a particularly difficult-to-treat population, according to the findings of a randomized controlled pilot trial conducted by researchers at the Medical University of South Carolina and the Ralph H. Johnson VA Medical Center. [More]
First-in-human study of cell bandage for common sporting knee injury shows promising results

First-in-human study of cell bandage for common sporting knee injury shows promising results

A 'living bandage' made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol. [More]
Kidneys from older deceased organ donors can function for years after transplantation, study finds

Kidneys from older deceased organ donors can function for years after transplantation, study finds

New research suggests that age cut-offs for deceased organ donors prevent quality kidneys from being available to patients in need of life-saving transplants. [More]
Researchers explore kidney biomarkers to track lupus progression

Researchers explore kidney biomarkers to track lupus progression

Lupus, a chronic autoimmune disease, can wreak havoc on an affected individual's body through inflammation, pain and even damage of the skin, joints and organs. [More]
Risks of dementia and Alzheimer's disease develop at high rates in older kidney transplant recipients

Risks of dementia and Alzheimer's disease develop at high rates in older kidney transplant recipients

Dementia and Alzheimer's disease develop at elevated rates in older kidney transplant recipients and may threaten the health of their transplanted organ as well as their own survival. [More]
GCS e-Santé Archipel 97-1 implements remote robotic ultrasound system for better patient treatment

GCS e-Santé Archipel 97-1 implements remote robotic ultrasound system for better patient treatment

The GCS e-Santé [Healthcare Cooperative Association for e-Health] Archipel 97-1 continues to develop the deployment and use of telemedicine in Guadeloupe and contributes to the improvement of medical treatment through new technologies. [More]
Scientists develop first functional biological pacemaker from human stem cells

Scientists develop first functional biological pacemaker from human stem cells

Scientists from the McEwen Centre for Regenerative Medicine, University Health Network, have developed the first functional pacemaker cells from human stem cells, paving the way for alternate, biological pacemaker therapy. [More]
New technology that increases Natural Killer cells to stop cancers gets licensed

New technology that increases Natural Killer cells to stop cancers gets licensed

Our bodies contain Natural Killer (NK) cells - an army that stops cancers and viruses before they can make us sick. [More]
Revolutionary approach could save lives of sickest patients waiting for liver transplant

Revolutionary approach could save lives of sickest patients waiting for liver transplant

There's new hope for patients with liver disease who are waiting for a donor liver to become available for transplantation. [More]
Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

Phenotypic Personalized Medicine could surmount treatment challenges for acute lymphoblastic leukemia

A team of UCLA bioengineers has demonstrated that its technology may go a long way toward overcoming the challenges of treatment for acute lymphoblastic leukemia, among the most common types of cancer in children, and has the potential to help doctors personalize drug doses. [More]
UNMC seeking patients with lymphoma to evaluate two-drug oral therapy

UNMC seeking patients with lymphoma to evaluate two-drug oral therapy

The University of Nebraska Medical Center is seeking 24 patients to enroll in a Phase 2a study to evaluate the safety and efficacy of two oral cancer drugs for patients with diffuse large B-cell lymphoma who have relapsed or are resistant to other traditional therapies. [More]
Study provides insights into biology of protein implicated in kidney disease

Study provides insights into biology of protein implicated in kidney disease

Investigators have discovered important information about apolipoprotein L1 (ApoL1), which can contribute to the development of various forms of kidney disease. [More]
Ground-breaking study to explore effectiveness of using pre-hospital blood products

Ground-breaking study to explore effectiveness of using pre-hospital blood products

University of Warwick is collaborating with researchers at the NIHR Surgical Reconstruction and Microbiology Research Centre to support a ground-breaking new study to investigate the effectiveness of giving patients blood products immediately after a major injury or trauma - before they reach hospital. [More]
Additions to standard therapy do not improve progression-free survival in patients with multiple myeloma

Additions to standard therapy do not improve progression-free survival in patients with multiple myeloma

Trial results being presented today during the 58th American Society of Hematology Annual Meeting and Exposition in San Diego suggest two therapies that are often added to standard therapy in patients with multiple myeloma do not improve rates of progression-free survival compared with the current standard course of treatment alone. [More]
Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Researchers find strong link between angiotensin receptor autoantibodies and increased risk of frailty

Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty. [More]
Experimental T-cell therapy shows promise in preventing AML relapse

Experimental T-cell therapy shows promise in preventing AML relapse

Fred Hutchinson Cancer Research Center announced promising results from an early trial in which patients with high-risk acute myeloid leukemia received genetically engineered immune cells. [More]
Simple, coordinated approach can improve chances of survival for high-risk AML patients

Simple, coordinated approach can improve chances of survival for high-risk AML patients

New research shows that quickly identifying patients with high-risk acute myeloid leukemia (AML), and speeding the process to find them a stem cell donor and performing the transplant earlier, can significantly improve their chances of surviving for at least two years after diagnosis without a relapse. [More]
Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

Combination of demineralized bone and gene therapy shows promise for treating pseudarthrosis

A team headed by Professor Albert Rizvanov, director of the Gene and Cell Technologies Open Lab, created a gene therapy drug that encodes growth factors for the stimulation of blood vessel and bone formation. [More]
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