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Gift of Hope Organ & Tissue Donor Network saves record number of lives in 2014

Gift of Hope Organ & Tissue Donor Network saves record number of lives in 2014

February 14th is National Donor Day. To celebrate, Gift of Hope Organ & Tissue Donor Network announced a record number of lives saved by helping 334 donors and their families donate 1,020 organs to patients waiting for a transplant, giving them a second chance at life last year. [More]
Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

Biotech experts to establish ethical guidelines in cellular biotechnology at BEINGS 2015

In May 2015 Atlanta will host Biotechnology and the Ethical Imagination: A Global Summit (BEINGS), an international summit drawing together the world's thought leaders on the highly debated issues of cellular biotechnology. [More]
Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Astute Medical previews upcoming AKI & CRRT 2015 conference to be held in San Diego

Astute Medical, Inc., developer of the NephroCheck® Test, today previewed the upcoming AKI & CRRT 2015 conference to be held in San Diego from February 17 to February 20. [More]
Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

Stem cell transplants more effective than mitoxantrone drug for people with severe multiple sclerosis

Stem cell transplants may be more effective than the drug mitoxantrone for people with severe cases of multiple sclerosis (MS), according to a new study published in the February 11, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Longer donor leukocyte telomere length linked to improved survival following HCT

Longer donor leukocyte telomere length linked to improved survival following HCT

Among patients with severe aplastic anemia who received stem cell transplant from an unrelated donor, longer leukocyte (white blood cells) telomere length (a structure at the end of a chromosome) was associated with increased overall survival at 5 years, according to a study in the February 10 issue of JAMA. [More]
Despite growing shortage of donor hearts, surgeons, transplant centers reject marginal hearts

Despite growing shortage of donor hearts, surgeons, transplant centers reject marginal hearts

Surgeons and transplant centers nationwide increasingly have rejected hearts donated for transplantation despite a growing need for them, according to a new study by researchers at the Stanford University School of Medicine. [More]
Synthetic DNA gel could bring researchers closer to printing artificial organs

Synthetic DNA gel could bring researchers closer to printing artificial organs

A two-part water-based gel made of synthetic DNA and peptide could bring the inventors of a 3D bio printer closer to being able to print organs for transplant, or to replace animal testing. The teams led by Dongsheng Liu (Tsinghua University) and Will Shu (Heriot-Watt University) faced two main challenges: finding a matrix or scaffold to support the live cells in 3D, and being able to produce a consistent product which would not be rejected by transplant recipients. [More]
New NIH grant to help restore function after spinal cord injury

New NIH grant to help restore function after spinal cord injury

Restoring function after spinal cord injury, which damages the connections that carry messages from the brain to the body and back, depends on forming new connections between the surviving nerve cells. While there are some delicate surgical techniques that reconnect the nerves, researchers are also looking at ways to restore the connections themselves at a cellular level. [More]
New research provides hope for treating stroke using HUCBCs

New research provides hope for treating stroke using HUCBCs

Researchers have known that transplanted human umbilical cord cells (HUCBCs) can have a restorative effect on the brain and brain function following a stroke. However, just how the cells exert their therapeutic effects has not been clear. Now, a research team from the University of South Florida using animal models of stroke has found that the HUCBCs are most beneficial in preventing neuron loss when the Akt signaling pathway is activated by secretions from the HUCBCs and that Akt activation subsequently impacts a specific gene involved in reducing inflammation. [More]
Japanese researchers explore use of bone marrow transplants to treat hypophosphatasia

Japanese researchers explore use of bone marrow transplants to treat hypophosphatasia

Recent research carried out by a team of researchers in Japan has investigated the use of bone marrow transplants (BMTs) to treat hypophosphatasia (HPP). In this study, the researchers carried out BMT for two infants with HPP in combination with allogenic (other-donated) mesenchymal stem cell transplants (MSCTs). The allogenic MSC donors were a parent of the infant. [More]
Researchers win $2.5 million DARPA contract to study prosthetic limb technology

Researchers win $2.5 million DARPA contract to study prosthetic limb technology

A research team led by Paul Marasco, Ph.D., of Cleveland Clinic's Lerner Research Institute, has won a $2.5 million contract from the Defense Advanced Research Projects Agency. The contract was awarded through DARPA's new Hand Proprioception and Touch Interfaces (HAPTIX) program, which aims to deliver naturalistic sensations to amputees and enable better control over their prosthetic limbs through direct connections to users' nervous systems. [More]
Risks and benefits of fecal microbiota transplant

Risks and benefits of fecal microbiota transplant

A woman successfully treated for a recurrent Clostridium difficile infection with stool from an overweight donor rapidly gained weight herself afterwards, becoming obese, according to a case report published in the new journal Open Forum Infectious Diseases. [More]
Researchers pinpoint key moments at which intervening decreases risk of death in hypertension patients

Researchers pinpoint key moments at which intervening decreases risk of death in hypertension patients

High blood pressure is the most common risk factor for heart disease and death worldwide, and yet the answers to some of the most basic questions about how to manage it - when to introduce new medications, intensify treatment or re-evaluate a patient - remain unclear. In a new study published this week in the British Medical Journal, researchers from Brigham and Women's Hospital examined the outcomes of 88,000 adults with hypertension to pinpoint the precise high-blood-pressure level and critical time points at which intervening was tied to a decrease in the risk of death. [More]
UM SOM launches ‘Program in Lung Healing’ to develop treatments for acute respiratory failure

UM SOM launches ‘Program in Lung Healing’ to develop treatments for acute respiratory failure

University of Maryland School of Medicine (UM SOM) Dean E. Albert Reece, MD, PhD, MBA, and Jeffrey A. Rivest, MS, President and Chief Executive Officer of University of Maryland Medical Center (UMMC), today announced the official launch of a new "Program in Lung Healing," that will further the School's position as a national leader in research, education and clinical innovation for acute ailments of the lung and respiratory system. [More]
Chemotherapy or immunosuppressive treatment may reactivate HBV

Chemotherapy or immunosuppressive treatment may reactivate HBV

Individuals previously infected with the hepatitis B virus (HBV) who receive chemotherapy or immunosuppressive treatment may be at risk of reactivating the disease according to a summary of report from the Emerging Trends Conference, "Reactivation of Hepatitis B," and published in Hepatology, a journal of the American Association for the Study of Liver Diseases. [More]
Three Keck Medicine scientists of USC receive $4.3 million from CIRM for stem cell research

Three Keck Medicine scientists of USC receive $4.3 million from CIRM for stem cell research

Three scientists from Keck Medicine of the University of Southern California have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine for research that includes creating a temporary liver for transplant patients, finding novel ways to treat immune disorders and blood diseases and developing a new animal model for exploring diseases like heart failure, diabetes and neurodegenerative diseases. [More]
FDA accepts Sangamo BioSciences' IND for SB-BCLmR-HSPC genome editing approach

FDA accepts Sangamo BioSciences' IND for SB-BCLmR-HSPC genome editing approach

Sangamo BioSciences, Inc. announced today that an Investigational New Drug (IND) application for the company's SB-BCLmR-HSPC genome editing approach, which is designed to provide a one-time lasting therapy for beta-thalassemia, has been accepted by the U.S. Food and Drug Administration and is now active. [More]
Anti-viral immune cells could inhibit bone marrow transplant infections caused by CMV

Anti-viral immune cells could inhibit bone marrow transplant infections caused by CMV

Bone marrow transplantation is a life-saving therapy for patients with blood cancers like leukemia or lymphoma. However, the depletion of the patient's immune system prior to transplantation can put patients at risk of for an infection by a virus called cytomegalovirus (CMV) that can be life threatening in these immune-compromised individuals. [More]
Morphogenesis, University of Florida partner to develop novel device to isolate rare cells

Morphogenesis, University of Florida partner to develop novel device to isolate rare cells

Senior engineering students and faculty at the University of Florida in Gainesville are partnering with biotech cell and gene therapy company Morphogenesis, Inc. in Tampa to design an advanced, fully automated cell separation system capable of capturing rare cells – such as stem cells – and circulating tumor cells. [More]
NQMBC recognizes Cancer Treatment Centers of America for providing quality breast cancer care

NQMBC recognizes Cancer Treatment Centers of America for providing quality breast cancer care

Cancer Treatment Centers of America at Midwestern Regional Medical Center has been recognized by the National Quality Measures for Breast Centers Program as being among the top centers in the country for providing quality breast cancer care. [More]