Transplant News and Research

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FDA approves cancer drug Afinitor for treatment of rare genetic disorder

The U.S. Food and Drug Administration approved the cancer drug Afinitor (everolimus) on Friday to treat patients with subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis (TS), a rare genetic disorder. This approval was for treatments of SEGA that can not be treated with surgery.

1 Nov 2010

Gore announces new Early TIPS for Ascites Study

W.L. Gore & Associates (Gore) today announced a new prospective, randomized, multi-center study at the Annual Meeting of the American Association for the Study of Liver Diseases. The hypothesis of the study is that early intervention with the GORE® VIATORR® TIPS Endoprosthesis improves transplant-free survival when compared to large volume paracentesis in patients with cirrhosis and difficult to treat ascites.

1 Nov 2010

Medivir's partner Tibotec reports Week 24 interim results from TMC435 Phase 2b study in HCV

Medivir AB, the research-based speciality pharmaceutical company focused on the development of high-value treatments for infectious diseases, notes that its development partner, Tibotec Pharmaceuticals, has announced the results of a Week-24 planned interim analysis of the Phase 2 response-guided PILLAR study for TMC435, Medivir's key pipeline asset, a hepatitis C protease inhibitor dosed once-daily.

1 Nov 2010

Race of donor may affect recurrent hepatitis C in patients after liver transplantation: Study

The race of liver donors may affect recurrent hepatitis C in patients after liver transplant, according to a study by Henry Ford Hospital. Patients receiving white cadaveric donor grafts had significantly more aggressive recurrent hepatitis C than those receiving grafts from African-American donors regardless of recipient race, says Matthew Moeller, M.D., gastroenterology fellow at Henry Ford Hospital and lead author of the study.

1 Nov 2010

Study determines long-term clinical outcome of patients posttransplant after anitviral therapy

Researchers from the University of Bari, Italy, concluded that treating patients after transplantation with antiviral therapy creates a sustained viral response (SVR) and protects them from liver-related deaths. The purpose of this study was to determine the long-term clinical outcomes of patients posttransplant who underwent antiviral therapy for recurrent hepatitis C virus (HCV) infection of the liver graft.

1 Nov 2010

Boehringer to present data of SOUND-C1 Phase Ib study for HCV treatment at AASLD Meeting

Boehringer Ingelheim announced results from a Phase Ib study, SOUND-C1, that showed the combination of two oral hepatitis C virus (HCV) compounds, the protease inhibitor BI 201335 and the polymerase inhibitor BI 207127, with ribavirin reduced viral load to the lower limit of quantifiable levels in HCV treatment-naïve patients.

1 Nov 2010

Salix to discuss XIFAXAN therapy for hepatic encephalopathy at AASLD 2010 Annual Meeting

Salix Pharmaceuticals, Inc. today announced that the 61st Annual Meeting of the American Association for the Study of Liver Diseases (AASLD 2010) will be an important venue for ongoing discussion of hepatic encephalopathy, or HE.

1 Nov 2010

Tibotec to present Week-24 interim analysis of PILLAR study for chronic HCV treatment at AASLD Meeting

Tibotec Pharmaceuticals announced today the company will present the results of a Week-24 planned interim analysis of the phase 2 response-guided PILLAR study in treatment-naive patients with chronic genotype 1 hepatitis C virus (HCV) at the 61st Annual Meeting of the American Association for the Study of Liver Diseases (AASLD) in Boston, MA., USA. The data will be presented as part of a late-breaker oral presentation on Monday, November 1.

1 Nov 2010

‘Off the shelf’ new livers from stem cells, glimmer of hope

A researcher team has successfully produced a small-scale version of a human liver in the laboratory using stem cells. This could be a boon for patients waiting for liver transplants although it will take years to perfect the procedure say researchers.

31 Oct 2010

UK HealthCare transplant recipient wins at 2010 U.S. Transplant Games

One transplant recipient from UK HealthCare, Dan Gutenson of Stanford, Ky., joined the 36 other members of "Team Kentucky" in Madison, Wisconsin for the 2010 U.S. Transplant Games this past summer. Gutenson, who received his kidney transplant in Sept. 2009, suffered from polycystic disease and received a kidney from a living donor in the church he pastors in Lincoln County, Ky.

30 Oct 2010

Brigham and Women's, and UI Hospitals and Clinics begin certification for SynCardia artificial heart implantation

SynCardia Systems, Inc. announced today that Brigham and Women's Hospital in Boston, and University of Iowa (UI) Hospitals and Clinics in Iowa City, Iowa, have begun certification to implant the SynCardia temporary Total Artificial Heart. Brigham and Women's will complete Phase I of certification on Nov. 1 & 2, and UI Hospitals and Clinics completed Phase I on Oct. 21 & 22.

30 Oct 2010

Memorial mass for former Loyola University Hospital cardiothoracic surgeon

A memorial Mass will be said on Friday, Nov. 12 for former Loyola University Hospital cardiothoracic surgeon Dr. Roque Pifarré, who performed the first heart transplant in Illinois.

29 Oct 2010

Access to kidney transplantation increases for elderly patients

Elderly patients with kidney failure get kidney transplants more often than they did a decade ago, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The results suggest that the chances of receiving a kidney transplant are better than ever for an older patient who needs one.

29 Oct 2010

Study finds impact of pre-transplant BMI on post liver transplant survival in pediatric population

A new study from the University of Washington reported obese children are at increased mortality risk in later years following primary liver transplantation (LT).

29 Oct 2010

StemCells initiates HuCNS-SC second clinical trial for Batten disease in children

StemCells, Inc. announced today that it has initiated a second clinical trial of its HuCNS-SC product candidate (purified human neural stem cells) in neuronal ceroid lipofuscinosis (NCL, also often referred to as Batten disease), a fatal neurodegenerative disorder in children.

29 Oct 2010

Gen-Probe third quarter research revenue increases 70% to $3.4 million

Gen-Probe Incorporated today reported financial results for the third quarter of 2010, highlighted by 19% growth in non-GAAP earnings per share (EPS) and 8% growth in product sales and total revenues.

29 Oct 2010

Slivers of frozen ovaries allow for childbirth later in life

According a US fertility expert, young women should freeze parts of their ovaries if they want to postpone motherhood until later in life. This advice came from Dr Sherman Silber at the American Society for Reproductive Medicine meeting in Denver.

28 Oct 2010

Immune system may play a role in cancer therapies: Study

The immune system may play a critical role in ensuring the success of certain types of cancer therapies, according to a new study by researchers at the Stanford University School of Medicine. The research showed treatments that disable cancer-promoting genes called oncogenes are much more successful in eradicating tumors in the presence of a signaling molecule secreted by kind of immune cell called a T helper cell.

28 Oct 2010

Systemic amyloidosis patient to receive triple organ transplant

In 2005, then 40-year-old Walt McGuire was playing hockey twice a week, working full-time and chasing his young daughter. Then one day, he noticed after one trip up the stairs to catch her, he couldn't catch his breath. A few days later his legs were swollen. After numerous trips to different doctors, McGuire finally was diagnosed with a rare blood disorder called amyloidosis.

28 Oct 2010

Essential Pharmaceuticals to commence sales of cell media products acquired from Lifeblood Medical

Essential Pharmaceuticals, LLC, a private company dedicated to providing specialty reagents and solutions to the life sciences market, announced today that the Company will commence sales and distribution of three distinct animal-component-free products: serum replacement, cryopreservation and clinical pathology media, formerly sold under the LiforCell® name.

28 Oct 2010

Transplant News and Research

FDA approves cancer drug Afinitor for treatment of rare genetic disorder

Gore announces new Early TIPS for Ascites Study

Medivir's partner Tibotec reports Week 24 interim results from TMC435 Phase 2b study in HCV

Race of donor may affect recurrent hepatitis C in patients after liver transplantation: Study

Study determines long-term clinical outcome of patients posttransplant after anitviral therapy

Boehringer to present data of SOUND-C1 Phase Ib study for HCV treatment at AASLD Meeting

Salix to discuss XIFAXAN therapy for hepatic encephalopathy at AASLD 2010 Annual Meeting

Tibotec to present Week-24 interim analysis of PILLAR study for chronic HCV treatment at AASLD Meeting

‘Off the shelf’ new livers from stem cells, glimmer of hope

UK HealthCare transplant recipient wins at 2010 U.S. Transplant Games

Brigham and Women's, and UI Hospitals and Clinics begin certification for SynCardia artificial heart implantation

Memorial mass for former Loyola University Hospital cardiothoracic surgeon

Access to kidney transplantation increases for elderly patients

Study finds impact of pre-transplant BMI on post liver transplant survival in pediatric population

StemCells initiates HuCNS-SC second clinical trial for Batten disease in children

Gen-Probe third quarter research revenue increases 70% to $3.4 million

Slivers of frozen ovaries allow for childbirth later in life

Immune system may play a role in cancer therapies: Study

Systemic amyloidosis patient to receive triple organ transplant

Essential Pharmaceuticals to commence sales of cell media products acquired from Lifeblood Medical

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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