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Fat-enclosed nanoparticles can directly irradiate brain tumor

For the past 40 years, radiation has been the most effective method for treating deadly brain tumors called glioblastomas. But, although the targeting technology has been refined, beams of radiation still must pass through healthy brain tissue to reach the tumor, and patients can only tolerate small amounts before developing serious side effects.

21 Mar 2012

MD Anderson, Transgenomic partner to evaluate use of ICE COLD-PCR

Transgenomic, Inc. today announced that it has begun a collaboration with The University of Texas MD Anderson Cancer Center to evaluate the use of the Company's very high sensitivity ICE COLD-PCR mutation detection technology in analysis of DNA isolated from circulating tumor cells (CTCs) in blood samples from patients with advanced cancer.

21 Mar 2012

Study shows how to defeat chemotherapy barrier in pancreatic cancer

Scientists at Fred Hutchinson Cancer Research Center and the Translational Genomics Research Institute (TGen) have discovered a literal 'break through' in pancreatic cancer.

21 Mar 2012

New drug makes chemotherapy more effective in treating acute myeloid leukemia

Doctors at Washington University School of Medicine in St. Louis have shown that a new drug makes chemotherapy more effective in treating acute myeloid leukemia, a cancer of the white blood cells. Instead of attacking these cells directly, the drug helps drive them out of the bone marrow and into the bloodstream, where they are more vulnerable to chemotherapy.

21 Mar 2012

Lexicon receives FDA Orphan Drug designation for telotristat etiprate to treat carcinoid syndrome

Lexicon Pharmaceuticals, Inc., announced today that the U.S. Food and Drug Administration (FDA) has granted its request for Orphan Drug designation for telotristat etiprate (LX1032) for the treatment of carcinoid syndrome.

21 Mar 2012

Jennerex initiates JX-594 plus irinotecan Phase 1/2 trial in metastatic colorectal cancer

Jennerex, Inc., a private clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic virus products for cancer, today announced that the first patient has been treated in a Phase 1/2 clinical trial of JX-594 in patients with metastatic colorectal cancer who have become refractory to chemotherapy and are either refractory to or ineligible for cetuximab.

20 Mar 2012

RaySearch receives PMH contract for new adaptive radiation therapy solution

RaySearch Laboratories AB has been awarded a contract for a new adaptive radiation therapy solution at Princess Margaret Hospital (PMH) in Toronto, Canada. This means that RaySearch will deliver its treatment planning system RayStation to PMH where it will be used as the primary treatment planning tool for adaptive radiation therapy.

20 Mar 2012

North Shore-LIJ inaugurates NYHNI's Center for Cranial Base Surgery at Lenox Hill Hospital

As part of its ongoing efforts to develop patient-centric services that focus on disease prevention and management, the North Shore-LIJ Health System today announced the creation of the New York Head and Neck Institute (NYHNI), a part of its head and neck surgery service line, and the opening of the Center for Cranial Base Surgery at Lenox Hill Hospital.

20 Mar 2012

Mayo Clinic researchers train mouse immune systems to eradicate skin cancer from within

Mayo Clinic researchers have trained mouse immune systems to eradicate skin cancer from within, using a genetic combination of human DNA from melanoma cells and a cousin of the rabies virus. The strategy, called cancer immunotherapy, uses a genetically engineered version of the vesicular stomatitis virus to deliver a broad spectrum of genes derived from melanoma cancer cells directly into tumors.

20 Mar 2012

FHCRC research represents potential breakthrough in treatment of pancreas cancer

Pancreas cancer tumors spread quickly and are notoriously resistant to treatment, making them among the deadliest of malignancies. Their resistance to chemotherapy stems in part from a unique biological barrier the tumor builds around itself. Now scientists at Fred Hutchinson Cancer Research Center have found a way to break through that defense, and their research represents a potential breakthrough in the treatment of pancreas cancer.

20 Mar 2012

Hedgehog and mTOR pathway are active in esophageal cancer

Identification of a non-traditional pathway for spiriting a cancer-promoting protein into the cell nucleus points to a possible combination therapy for esophageal cancer and indicates a mechanism of resistance for new drugs that attack the Hedgehog pathway.

20 Mar 2012

Researchers discover new method to identify cancer-causing translocations

Researchers from Huntsman Cancer Institute (HCI) at the University of Utah report they have discovered a method to identify cancer-causing rearrangements of genetic material called chromosomal translocations quickly, accurately, and inexpensively.

20 Mar 2012

BSD-500 Hyperthermia System installed at Fort Belvoir Community Hospital

BSD Medical Corporation announced today the purchase, installation and acceptance of a BSD-500 Hyperthermia System (BSD-500) by Fort Belvoir Community Hospital (Fort Belvoir).

19 Mar 2012

Scientist generates mutant version of IL-2 protein to treat advanced cancers

The utility of a naturally occurring protein given, sometimes to great effect, as a drug to treat advanced cancers is limited by the severe side effects it sometimes causes. But a Stanford University School of Medicine scientist has generated a mutant version of the protein whose modified shape renders it substantially more potent than the natural protein while reducing its toxicity.

19 Mar 2012

Gamma Knife surgery stops growth of 'World's tallest living human'

Sultan Kosen won't be posting new world records for height anymore, but that's just fine with him. The Gamma Knife radiosurgery the 29-year-old Turkish man had in August 2010 has successfully stopped his growth at the height of 8 ft 3 in (251 cm). Mr. Kosen, who suffered the effects of acromegaly, has held the title of "World's Tallest Living Human" since September 2009, when his 8 ft plus stature edged 7 ft 9 in Xiu Xung from China.

From Elekta 17 Mar 2012

Oral BRAF inhibitor can extend survival to 16 months for patients with MM

An international team of researchers from the United States and Australia, including researchers at Moffitt Cancer Center in Tampa, Fla., have found that the oral BRAF inhibitor vemurafenib (PLX4032) when tested in a phase II clinical trial offered a high rate of response in patients with previously treated metastatic melanoma and who had the BRAF mutation.

17 Mar 2012

CCN1 protein orchestrates cellular antiviral response in the extracellular matrix

Brain-tumor cells that are infected with a cancer-killing virus release a protein "alarm bell" that warns other tumor cells of the impending infection and enables them to mount a defense against the virus, according to a study led by researchers at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

16 Mar 2012

New FSU technology could decrease the cost of drug discovery

New technology being developed at Florida State University could significantly decrease the cost of drug discovery, potentially leading to increased access to high-quality health care and cancer patients receiving personalized chemotherapy treatments.

16 Mar 2012

Two awards to advance pancreatic cancer research

The Pancreatic Cancer Action Network and the American Association for Cancer Research have awarded Stephanie K. Dougan, Ph.D., postdoctoral fellow at the Whitehead Institute for Biomedical Research, and Oliver G. McDonald, M.D., Ph.D., postdoctoral fellow at Johns Hopkins University, the 2012 Pancreatic Cancer Action Network-AACR Pathway to Leadership Grants.

16 Mar 2012

State roundup: Ariz. long-term care plan advances; N.H. moves to repeal 'certificate-of-need'; Minn. ALEC legislation

The Senate Appropriations Committee unanimously passed a bill Tuesday that would make long-term health care more affordable for middle-class families. Rep. Steve Farley, D-Tucson, sponsored House Bill 2713, which would allow Arizonans to set aside money in a tax-deductible savings account to pay for long-term health-care expenses. It would also create tax deductions for long-term health insurance premiums.

16 Mar 2012