Tumor Necrosis Factor News and Research

RSS

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

A new paper recently published in Nature, reported the examination of synovial tissue from the joints of nearly 80 people with RA, in combination with RNA sequencing and surface protein analyses.

10 Nov 2023

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

The role of interleukin (IL)-6 and IL-1α in sterile intraamniotic inflammation (SIAI), a condition associated with preterm birth (PTB).

9 Nov 2023

Charting the future of IBD treatment: From immune modulators to microRNA therapies

In a recent study published in the journal eGastroenterology, researchers delved into the latest therapeutic strategies for managing inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The paper discusses emerging treatments ranging from immune-modulating drugs and biologics to novel approaches like microRNA upregulators and stem cell therapies, highlighting the need for precision medicine in IBD care.

8 Nov 2023

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, found that JAK inhibitors (JAKi) and tocilizumab elicited better response rates in VEXAS syndrome compared to other targeted therapies.

7 Nov 2023

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

According to new research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, continuing tumor necrosis factor inhibitors during pregnancy is not associated with worse fetal or obstetric outcomes and may reduce the risk of severe maternal infections during pregnancy (Abstract #0477).

7 Nov 2023

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases (IBD) that affect the gastrointestinal tract.

7 Nov 2023

Study shows depression increases disability risk in rheumatoid arthritis sufferers

The interactions between rheumatoid arthritis (RA) and major depressive disorder (MDD).

7 Nov 2023

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Researchers have mapped the complex epigenetic and transcriptomic landscape of cancer, revealing key regulatory elements across 11 tumor types that could unlock new insights into cancer progression and metastasis.

5 Nov 2023

Mast cell receptor linked to alcohol withdrawal-associated headaches

Researchers investigate the role of the mast-cell-specific receptor Mas-related G-protein-coupled receptor B2 (MrgprB2) in alcohol-withdrawal-induced headaches.

2 Nov 2023

NF-κB activation during COVID-19 and its impact on patients with hypertension

Researchers review the role of NF-κB activation in the replication of SARS-CoV-2 and the impact of COVID-19 medications on NF-κB activation.

25 Oct 2023

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

The therapeutic potential of resveratrol, a red grape polyphenol.

25 Oct 2023

How the gut microbiome contributes to schizophrenia

Researchers explore potential relationships between schizophrenia, the gut microbiome, the gut-brain axis, and short-chain fatty acids.

19 Oct 2023

How African sleeping sickness melts away body fat: New study sheds light on the role of lipolysis

Researchers find that the T. brucei parasite, responsible for African trypanosomiasis, triggers weight loss by disrupting fat cell lipolysis. The study shows that ATGL enzyme is key to this process, potentially offering a new angle for future research and treatment.

17 Oct 2023

Are migraines linked to gut health and chronic non-communicable diseases?

The Links Between Migraines, Gut Health, and Chronic Non-Communicable Diseases (CNCDs).

13 Oct 2023

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

In a recent review published in Immunity, researchers reviewed tumor-immunity cycle data.

13 Oct 2023

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

The research paper explores the multifaceted role of the IL-17 family in immune response, covering everything from infection control to pathological conditions like autoimmune diseases and cancer. Future therapies may exploit IL-17's unique signaling pathways to offer more targeted and cost-effective treatments.

12 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Researchers reviewed existing data on the neurodegenerative effects of astrocyte-derived lipocalin-2 (LCN-2).

4 Oct 2023

What are the pharmacological properties of black goji berries?

The pharmacological effects of the components of Lycium ruthenicum Murray fruits.

29 Sep 2023

Can COVID-19 vaccines turn the tide on long-haul symptoms?

The study finds that COVID-19 vaccination can significantly reduce symptoms and improve well-being in patients suffering from post-COVID-19 conditions (PCC). Vaccination also lowered systemic markers of inflammation but did not entirely eliminate persistent SARS-CoV-2 antigens, which may continue to contribute to inflammation.

22 Sep 2023

Tumor Necrosis Factor News and Research

Research redefines rheumatoid arthritis: Over 314,000 cells analyzed for precise treatment strategies

New hope for preventing preterm births: IL-6R blockade reduces neonatal mortality

Charting the future of IBD treatment: From immune modulators to microRNA therapies

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

Using TNF inhibitors during pregnancy not associated with worse fetal or obstetric outcomes

Novel and emerging therapies offer new hope for patients with inflammatory bowel disease

Study shows depression increases disability risk in rheumatoid arthritis sufferers

Atlas of cancer's hidden rules: Unveiling the transcriptomic and epigenetic secrets across 11 tumors

Mast cell receptor linked to alcohol withdrawal-associated headaches

NF-κB activation during COVID-19 and its impact on patients with hypertension

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

How the gut microbiome contributes to schizophrenia

How African sleeping sickness melts away body fat: New study sheds light on the role of lipolysis

Are migraines linked to gut health and chronic non-communicable diseases?

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

IL-17: The molecule that could revolutionize autoimmune and cancer treatments

Effectiveness of Lactobacillus in treating inflammatory bowel disease

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

What are the pharmacological properties of black goji berries?

Can COVID-19 vaccines turn the tide on long-haul symptoms?

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News