Tumorigenesis News and Research RSS Feed - Tumorigenesis News and Research

Tumorigenesis is the process involved in the production of a new tumor or tumors.
New ULB study shows how cancer cell of origin controls malignant transition

New ULB study shows how cancer cell of origin controls malignant transition

Researchers at the Université libre de Bruxelles, ULB define for the first time how the cancer cell of origin controls invasive and metastatic properties of tumor cells. [More]
Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study. [More]
Breakthrough research links sphingolipid-mediated cell junctions and tumorigenesis

Breakthrough research links sphingolipid-mediated cell junctions and tumorigenesis

Almost all cell types exhibit some sort of polarity, which enables them to carry out specialized functions. Adherens junctions, which consist of the transmembrane protein cadherin and the intracellular components beta-catenin, alpha-catenin, and actin filaments, initiate cell-cell contacts and maintenance of cell polarity. [More]
Clinical Genomics’ blood test detects twice the number of colorectal cancer recurrence cases than CEA testing

Clinical Genomics’ blood test detects twice the number of colorectal cancer recurrence cases than CEA testing

Clinical Genomics, a private company developing innovative diagnostic tools for colorectal cancer, today announced that data supporting its two-gene circulating tumor DNA (ctDNA) blood test for post-surgical monitoring of colorectal cancer (CRC) recurrence have been published online by Cancer Medicine, and will appear in the October issue. [More]
Specific high-fat diets linked to increased tumor formation in mouse model of intestinal cancer

Specific high-fat diets linked to increased tumor formation in mouse model of intestinal cancer

A high-fat-diet-induced immune reaction causes inflammation leading to intestinal cancer in a mouse model - even among animals that are not obese -- according to a new study from the Perelman School of Medicine at the University of Pennsylvania, Case Western Reserve University, the Pacific Northwest Research Institute, and others. [More]
Researchers use novel technique to unravel key mystery of earliest stage of development

Researchers use novel technique to unravel key mystery of earliest stage of development

A Ludwig Cancer Research study published online September 14th in Nature reports a novel technique to map specific chemical (or "epigenetic") modifications made to the protein packaging of DNA using a small population of cells. [More]
Study identifies new gene that suppresses breast cancer in mice

Study identifies new gene that suppresses breast cancer in mice

In recent years, the incidence of breast cancer has been increasing worldwide, and breast cancer is becoming a serious object of public concern. [More]
Researchers identify tantalizing target in fight against aggressive form of lung cancer

Researchers identify tantalizing target in fight against aggressive form of lung cancer

Researchers at the University of Virginia School of Medicine have discovered a flaw in the armor of the most aggressive form of lung cancer, a weakness that doctors may be able to exploit to slow or even stop the disease. [More]
Fruit fly models may help scientists understand underlying mechanism of HPV-induced cancer

Fruit fly models may help scientists understand underlying mechanism of HPV-induced cancer

Human papillomavirus (HPV) is one of the most common sexually transmitted infections in the United States and has been identified as a primary cause of cervical cancer in women. [More]
Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

Review highlights interconnected roles of apoptosis, cellular senescence in cancer and aging

A common feature of cancer and aging is cells' reduced ability to respond to stress-induced damage to DNA or cellular structures. [More]
Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Researcher identifies how Itch protein inhibits colonic inflammation and carcinogenesis

Venuprasad Poojary, PhD, an associate investigator at Baylor Institute for Immunology Research (BIIR), part of Baylor Scott & White Research Institute, reported this week in the journal Nature Immunology the role of a key protein in the regulatory pathway that is involved in limiting colon inflammation and tumor growth. [More]
TSRI scientists identify GlyRS protein that launches cancer growth

TSRI scientists identify GlyRS protein that launches cancer growth

Scientists at The Scripps Research Institute have identified a protein that launches cancer growth and appears to contribute to higher mortality in breast cancer patients. [More]
TSRI study shows how specific gene mutation promotes growth of aggressive tumors

TSRI study shows how specific gene mutation promotes growth of aggressive tumors

Scientists at The Scripps Research Institute have caught a cancer-causing mutation in the act. A new study shows how a gene mutation found in several human cancers, including leukemia, gliomas and melanoma, promotes the growth of aggressive tumors. [More]
Common pain and anti-inflammation drugs may slow cancer growth

Common pain and anti-inflammation drugs may slow cancer growth

Scientists from the Florida campus of The Scripps Research Institute have found that one of the most widely prescribed pain and anti-inflammation drugs slows the growth rate of a specific kind of cancer in animal models and suggests the medication could have the same effect on other types of tumors. [More]
Malicious form of ATF2 protein drives formation of melanoma

Malicious form of ATF2 protein drives formation of melanoma

An international collaborative study led by scientists at the Sanford Burnham Prebys Medical Discovery Institute has identified a malicious form of a protein that drives the formation of melanoma. [More]
OSMR gene plays key role in driving growth of glioblastoma tumors

OSMR gene plays key role in driving growth of glioblastoma tumors

Glioblastoma is the most aggressive type of brain tumor in adults. Unfortunately, there are no effective treatments for the disease. On average, patients succumb just 16 months after diagnosis. [More]
Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Head and neck cancers (HNC) are the sixth most common cancers worldwide, with approximately 600,000 new cases diagnosed every year. [More]
Scientists resolve tumor heterogeneity using innovative DEPArray technology

Scientists resolve tumor heterogeneity using innovative DEPArray technology

Using the innovative DEPArray technology, scientists at Silicon Biosystems, a Bologna (Italy) and San Diego (CA, USA) based biotech company, were able to solve one of the biggest limitation in the study of cancer genetic: tumor samples heterogeneity. [More]
Study reveals link between genomic instability, aneuploidy and cancer

Study reveals link between genomic instability, aneuploidy and cancer

A recent analysis of 43,205 human tumours unveiled that 68% of solid tumours are aneuploid, that is to say, they have an altered number of chromosomes. In recent years, scientists have attempted to clarify whether this aneuploidy contributes to tumour development or whether it is a co-lateral effect of the genomic instability of cancer cells, which increase the rate of mutations and the likelihood of cancer. [More]
Using acidity to detect cancer

Using acidity to detect cancer

Normally, tissues demonstrate a slightly acidic intracellular pH (pHi) and slightly alkaline extracellular pH (pHe). However, proliferating tissues demonstrate transient pH Gradient Reversal i.e. alkalinization of pHi and acidification of pHe. [More]
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