Tumorigenesis News and Research

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Tumorigenesis is the process involved in the production of a new tumor or tumors.

Overexpression of lncRNA MVIH may serve as a potential diagnostic biomarker in cervical cancer

A new research paper was published in Genes & Cancer on November 23, 2022, entitled, "Ectopic expression of lncRNA MVIH as a potential diagnostic biomarker in cervical cancer."

9 Dec 2022

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Fatty foods harm our health. Prior research has established a link between the consumption of dietary fats and non-alcoholic fatty liver disease, which subsequently leads to inflammation and tumor formation in the liver.

7 Dec 2022

Parasites associated with leprosy may have the ability to regenerate livers

Leprosy is one of the world's oldest and most persistent diseases but the bacteria that cause it may also have the surprising ability to grow and regenerate a vital organ.

15 Nov 2022

Increased paternal age may give rise to disease in the new generation

In a new study, researchers assessed the effects of paternal age on novel mutations and diseases in the next generation.

8 Nov 2022

Fermented dairy products can improve gut mucosal immunity

In a recent study published in the journal Immunology Letters, researchers assessed the role of fermented dairy products and dairy starters in modulating gut mucosal immunity.

3 Nov 2022

Commensal gut microbes from IBD patients produce genotoxic metabolites

Functional screening of human gut microbiota reveals a family of small molecule genotoxins called indolimines in patients with inflammatory bowel disease (IBD), according to a new study.

27 Oct 2022

Scientists discover molecular link between lung tumor growth and disrupted circadian rhythms

Scientists discovered an important molecular link between lung tumor growth and disrupted circadian rhythms, according to a new paper co-authored by a University of Rochester Wilmot Cancer Institute investigator and led by the Scripps Research Institute in California.

21 Oct 2022

Researchers discover potential therapeutic target for deadly brain tumors

Researchers at VCU Massey Cancer Center discovered a cellular partnership that drives the growth of deadly brain tumors and could potentially serve as a novel target for disease treatment.

5 Oct 2022

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

In a new study, researchers evaluated the anti-cancer therapeutic efficacy of two structurally-unrelated small molecules, PAV-617 and PAV-951.

4 Oct 2022

Changes in temperature may be behind the link between circadian disruption and cancer

Disruptions in circadian rhythm-;the ways that our bodies change in response to the 24-hour light and dark cycle-;have been linked to many different diseases, including cancer.

28 Sep 2022

Study finds telomeres can set damage thresholds for cancer cells above which they cannot continue to divide

A recent study hypothesized that ALT might compromise telomere integrity if not restricted appropriately.

21 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

CRISPR/Cas9 is a commonly used, very precise, gene editing technique whose development, by Jennifer A. Doudna and Emmanuelle Charpentier, was recognised with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors", CRISPR allows the introduction of the desired DNA sequence into (virtually) any spot of the genome, thus modifying or inactivating a gene. This technique is widely used in biomedical research and some CRISPR-based therapies are in clinical trials for the treatment of human blood disorders, some types of cancer and HIV, among other conditions.

10 Aug 2022

Tumorigenesis News and Research

Overexpression of lncRNA MVIH may serve as a potential diagnostic biomarker in cervical cancer

Study shows how dietary saturated/trans fats promote liver tumorigenesis

Parasites associated with leprosy may have the ability to regenerate livers

Increased paternal age may give rise to disease in the new generation

Fermented dairy products can improve gut mucosal immunity

Commensal gut microbes from IBD patients produce genotoxic metabolites

Scientists discover molecular link between lung tumor growth and disrupted circadian rhythms

Researchers discover potential therapeutic target for deadly brain tumors

Small antiviral molecules termed assembly modulators show therapeutic efficacy against cancer

Changes in temperature may be behind the link between circadian disruption and cancer

Study finds telomeres can set damage thresholds for cancer cells above which they cannot continue to divide

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

IRB scientists identify critical spots on the genome where gene editing could cause an unwanted response

Cytokine-based cancer immunotherapy: current progress and future prospects

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

Exploring the impact of bacterial infection and gut microbiome on colorectal cancer development

New technique can accurately detect viruses in tumors from clinical next-generation sequencing

Japanese researchers discover new mechanisms of action by extracellular vesicles in lymphoma

Active compound in Chinese herbs prevents colon cancer in mice

MAIT cells exercise complex functions and may be targets for future immunotherapies and vaccines

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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