Valproic Acid News and Research

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Valproic Acid is a drug used to treat epileptic seizures and bipolar disorder and to prevent migraine headaches. It is also being studied in the treatment of Kaposi sarcoma. It is a type of anticonvulsant, antimaniacal, and migraine headache prophylactic.

Eternal youth? Chemical cocktails prove effective in cell age reversal

Researchers identified chemical drug combinations that could reverse cellular aging.

19 Jul 2023

New strategies to beat rare tumors of the adrenal gland

Only one in 100,000 people suffer from a pheochromocytoma, a tumor of the adrenal gland. If the tumor has already metastasized, a radioactive compound can be used to detect malignant cells that have spread to other parts of the body, and to irradiate them from the inside.

9 Feb 2023

UC San Francisco neurologists focus on the hazards of abortion restrictions for women of reproductive age

UCSF Perspective Article Says New Ruling May Result in Increased Risk of Deaths, Disability.

14 Jul 2022

Taking valproic acid during pregnancy can cause birth defects, study shows

Valproic acid-; a drug used to treat epilepsy, migraine, and bipolar disorder-; can cause birth defects when taken during pregnancy.

14 Jun 2022

Direct differentiation of progenitor stem-like cells into mesenchymal stem, and osteogenic cells

Epithelial cell rests of Malassez derived from the periodontal ligament were transformed into progenitor stem-like cells by stimulation with epigenetic agents.

22 Mar 2021

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Lithium is considered the gold standard for treating bipolar disorder (BD), but nearly 70 percent of people with BD don't respond to it.

5 Jan 2021

Antiseizure drug use during pregnancy linked with double the risk of having children with autism

Women with epilepsy who take the antiseizure drug valproic acid while pregnant are at more than double the risk of having children with autism spectrum disorder and nearly double the risk of having children with attention deficit hyperactivity disorder (ADHD), according to a study in the October 28, 2020, online issue of Neurology, the medical journal of the American Academy of Neurology.

28 Oct 2020

Transcriptomics identifies possible COVID-19 therapies

By using a diverse set of transcriptomic SARS-CoV-2 signatures, US researchers put to use their previously developed drug repositioning pipeline to pinpoint potential drug candidates for the treatment of coronavirus disease (COVID-19). The study is currently available on bioRxiv preprint server.

26 Oct 2020

Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020

Meta-analysis of latest second-line treatments for status epilepticus

Status epilepticus (SE) is the most common neurologic emergency, with rates estimated between 1.3 and 81 cases per 100,000 people per year.

27 May 2020

Combination treatment reduces breast cancer development in mice

Adding a medication used to treat epilepsy, bipolar disorder and migraines to a blood pressure medicine reversed some aspects of breast cancer in the offspring of mice at high risk of the disease because of the high fat diet fed to their mothers during pregnancy.

30 Dec 2019

Six ways physicians can help optimize reproductive health in women with epilepsy

Worldwide, more than 15 million women of childbearing age have epilepsy. Each year about 600,000 of them become pregnant.

20 Nov 2019

Finding innovative treatments to help patients with traumatic brain injury

To treat a traumatic brain injury, researchers are thinking outside the box.

22 Aug 2019

FDA approves antibacterial drug to treat complicated urinary tract infections, intra-abdominal infections

The U.S. Food and Drug Administration has approved Recarbrio (imipenem, cilastatin and relebactam), an antibacterial drug product to treat adults with complicated urinary tract infections (cUTI) and complicated intra-abdominal infections (cIAI).

17 Jul 2019

New experimental system can rapidly assess pathogenic effects of a drug on baby's brain

Pregnant women are often advised to avoid certain drugs because of potential risks to their unborn infant's growing brain cells.

18 Jun 2019

$Reformulated epileptic drug reaches first clinical trial for medically refractory epilepsy$

Valproic Acid News and Research

Further Reading

Eternal youth? Chemical cocktails prove effective in cell age reversal

New strategies to beat rare tumors of the adrenal gland

UC San Francisco neurologists focus on the hazards of abortion restrictions for women of reproductive age

Taking valproic acid during pregnancy can cause birth defects, study shows

Direct differentiation of progenitor stem-like cells into mesenchymal stem, and osteogenic cells

Study: Decreased activation of LEF1 gene disrupts ordinary neuronal function

Antiseizure drug use during pregnancy linked with double the risk of having children with autism

Transcriptomics identifies possible COVID-19 therapies

Valproic acid can interact with DNA conformation and regulate gene expression

Meta-analysis of latest second-line treatments for status epilepticus

Combination treatment reduces breast cancer development in mice

Six ways physicians can help optimize reproductive health in women with epilepsy

Finding innovative treatments to help patients with traumatic brain injury

FDA approves antibacterial drug to treat complicated urinary tract infections, intra-abdominal infections

New experimental system can rapidly assess pathogenic effects of a drug on baby's brain

Reformulated epileptic drug reaches first clinical trial for medically refractory epilepsy

Alzheimer's patients using antiepileptic drugs have twice the risk of pneumonia, study shows

Scientists reprogram mature inhibitory neurons into dopaminergic cells

Research suggests link between epilepsy and bipolar disorder

Valproic acid exposure results in characteristics linked to autism, zebrafish study shows

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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