Warfarin News and Research

RSS

Warfarin is a drug that prevents blood from clotting. It belongs to the family of drugs called anticoagulants (blood thinners).

Reducing aspirin use in patients treated with common blood thinner prevents bleeding complications

If you're already taking one blood thinner, mounting research suggests you might not need to take a second one.

19 Sep 2022

Formulary restrictions may increase the risk of stroke in patients with atrial fibrillation

Atrial fibrillation (AF) is a major risk factor for stroke, and for decades the anticoagulant warfarin was the standard treatment for lowering that hazard. However, numerous drug and food interactions make warfarin burdensome for patients.

10 Aug 2022

Fully reduced form of vitamin K found to efficiently inhibit ferroptotic cell death

A team of researchers at Tohoku University has reported on a novel function of vitamin K, which is generally known for its importance in blood clotting.

4 Aug 2022

Many treatments for intracerebral hemorrhage are not as effective as previously thought, guideline suggests

Some treatments or preventive therapies used to manage intracerebral hemorrhages (ICH), or a bleeding stroke, are not as effective as previously believed, according to the new American Heart Association/American Stroke Association guideline for caring for people with spontaneous ICH, published today in the Association's Stroke journal.

17 May 2022

Assessment of England's medication prescribing safety during COVID pandemic

In a recent study posted to the medRxiv* preprint server, researchers assessed the impact of coronavirus disease 2019 (COVID-19) on the prescribing safety of high-risk medications on a national scale in England.

11 May 2022

Potential antiviral targets in SARS-CoV-2

Researchers assessed potential targets in severe acute respiratory syndrome coronavirus 2.

6 May 2022

Calcium supplements may increase risk of death in older people with aortic valve stenosis

Calcium supplements, frequently given to older people to lessen the risk of brittle bones (osteoporosis) and fractures, are linked to a heightened risk of death among those with aortic valve stenosis, a progressive and potentially fatal condition, finds research published online in the journal Heart.

26 Apr 2022

Leakage after left atrial appendage occlusion associated with higher risk of adverse events

Patients who had leakage to the left atrial appendage due to incomplete device sealing after left atrial appendage occlusion (LAAO) experienced more clotting and bleeding events within a year following their procedure compared with patients who had no leaking, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

New blood-clotting test uses only a single drop of blood and smartphone

Blood clots form naturally as a way to stop bleeding when someone is injured. But blood clots in patients with medical issues, such as mechanical heart valves or other heart conditions, can lead to a stroke or heart attack.

11 Feb 2022

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Direct oral anti-coagulant (anti-clotting) (DOAC) medications that target a single clotting factor work just as well to prevent future clots as the older, less-specific medication warfarin.

11 Feb 2022

Commonly prescribed anticoagulants may increase UTI severity

New research by the Centenary Institute suggests that commonly prescribed anticoagulants – medicines, such as aspirin, that help prevent blood clots – may make urinary tract infections (UTIs) more severe.

17 Nov 2021

Anticoagulation treatment may prevent cognitive decline in older atrial fibrillation patients

The anticoagulant medication dabigatran yielded similar results to warfarin for the prevention of cognitive decline in older adults with atrial fibrillation after two years of treatment, according to late-breaking research presented today at the American Heart Association's Scientific Sessions 2021.

15 Nov 2021

BioIVT to highlight the use of SCHH model to investigate drug-drug interaction of bempedoic acid

BioIVT, a leading provider of research models and services for drug and diagnostic development, is hosting a webinar in which researchers will discuss how they used a sandwich-cultured human hepatocyte (SCHH) model to investigate the drug-drug interaction (DDI) potential of bempedoic acid, a drug that was recently approved to treat hypercholesterolemia.

9 Nov 2021

Nine of ten patients with hypertension do not receive enough treatment

Hypertension (high blood pressure) is the leading treatable cause of illness and death worldwide. More than a billion people are hypertensive, defined as having blood pressure (BP) with a systolic level (the higher number) of at least 140 millimeters of mercury (mmHg) or diastolic level (the lower number) of 90 mmHg or higher.

28 Jul 2021

AMP’s new consensus can promote standardization of PGx gene/allele testing, improve patient care

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP2D6 assays, promote standardization of testing across different laboratories and improve patient care

11 Jun 2021

Study shows a protective association between anticoagulants and COVID-19

In a new study, researchers investigated the association between the use of oral anticoagulants and warfarin in COVID-19 disease outcomes. They published their results in a paper on the medRxiv* preprint server.

3 May 2021

Study shows adverse outcomes associated with use of more blood thinners

More blood thinners aren't automatically better, another study confirms. A new publication in JAMA Internal Medicine focuses on the minimal pros and the concerning cons of combining a daily aspirin with a drug from the newer class of anticoagulants that include apixaban, dabigatran, edoxaban and rivaroxaban.

19 Apr 2021

Understanding stroke and heart disease in women remains a major research priority

Understanding the sex differences in cardiovascular disease presentation and outcomes remains a major research priority demonstrated by the record number of submissions for this year's Go Red for Women® special issue of the American Heart Association's flagship journal Circulation, published online today.

17 Feb 2021

Study: Aspirin should be favored to prevent blood clots in children after complex heart surgery

Aspirin should be favored over warfarin to prevent blood clotting in children who undergo a surgery that replumbs their hearts, according to a new study.

14 Feb 2021

Pharmacologist lays out a plan to improve the equity of drug development

In a new perspective piece published in the Feb. 5 issue of Science, pharmacologist Namandje Bumpus, Ph.D. -- who recently became the first African American woman to head a Johns Hopkins University School of Medicine department, and is the only African American woman leading a pharmacology department in the country -- outlines the molecular origins for differences in how well certain drugs work among distinct populations.

4 Feb 2021