Warfarin News and Research

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Warfarin is a drug that prevents blood from clotting. It belongs to the family of drugs called anticoagulants (blood thinners).

Anticoagulant drug linked to greater risk of knee and hip replacements in patients with osteoarthritis

New research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vitamin K drug widely prescribed to prevent blood clots, is associated with a significantly greater risk of knee and hip replacements in patients with osteoarthritis.

6 Nov 2020

Educational mailing for atrial fibrillation patients fails to increase uptake of stroke prevention drugs

An educational mailing for atrial fibrillation patients and their clinicians did not increase uptake of stroke prevention drugs, according to results of the IMPACT-AFib trial presented in a Hot Line session today at ESC Congress 2020.

1 Sep 2020

ESC and EACTS develop guidelines for diagnosis and management of atrial fibrillation

ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association of Cardio-Thoracic Surgery (EACTS).

31 Aug 2020

Cannabinoids may alter the effects of some prescription drugs

Cannabinoid-containing products may alter the effects of some prescription drugs, according to Penn State College of Medicine researchers.

3 Aug 2020

Vitamin K may offer protective health benefits as we age, study suggests

A new, multi-ethnic study found older adults with low vitamin K levels were more likely to die within 13 years compared to those whose vitamin K levels were adequate.

15 Jun 2020

Incidence of intracerebral hemorrhages increasing in older people, study finds

Brain bleeds called intracerebral hemorrhages remained stable in incidence among all age groups over the past 30 years, but they increased in people 75 and older, according to a new analysis of the Framingham Heart Study. The findings are in JAMA Neurology.

8 Jun 2020

AMP publishes evidence-based recommendations to standardize clinical genotyping tests for warfarin response

The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, today published consensus, evidence-based recommendations to aid in the design, validation and interpretation of clinical genotyping tests for the prediction of warfarin response.

6 May 2020

AAN publishes updated practice advisory on closure of common heart defect after stroke

New guidance from the American Academy of Neurology concludes that closure of a common heart defect called a patent foramen ovale may be recommended for some people who have had a stroke.

29 Apr 2020

Excess cardiac myosin worsens damage to heart tissue during a heart attack

A prevalent heart protein known as cardiac myosin, which is released into the body when a person suffers a heart attack, can cause blood to thicken or clot--worsening damage to heart tissue, a new study shows.

2 Apr 2020

How cannabis interacts with medications

A new practice guideline published in the journal CMAJ in February 2020 describes five types of drug interactions possible with the use of cannabis. Cannabis is a plant-derived drug containing the psychoactive ingredient delta-9-tetrahydrocannabinol (THC) and non-psychoactive cannabidiol (CBD). These cannabinoids are broken down by the liver enzymes cytochrome P450 C(YP)34A, and CYP2CC9.

2 Mar 2020

Five things to know about drug interactions with cannabinoids

A practice article provides 5 things to know on how drugs can interact with cannabinoids in CMAJ.

2 Mar 2020

Secondary analysis reinforces safety of blood thinner

Treatment with the blood thinner apixaban was associated with a lower risk of bleeding, death and hospitalization compared with warfarin, regardless of history of prior stroke or blood clot, according to a secondary analysis presented as late breaking science today at the American Stroke Association's International Stroke Conference 2020.

23 Feb 2020

Study finds racial, ethnic disparities in stroke prevention among patients undergoing dialysis

In a study of patients with kidney failure and atrial fibrillation, racial/ethnic minorities experienced higher rates of stroke compared with non-Hispanic White patients, and they were less likely to fill prescriptions of stroke-preventive medications.

20 Feb 2020

Doctors should warn cardiology patients about the risk of marijuana use, say researchers

A team led by investigators at Brigham and Women's Hospital has stated that cardiology patients should be warned and counseled about the potential risks of using marijuana until further evidence is available.

20 Jan 2020

Geospatial model helps compare costs of different anticoagulant therapies

Appropriately selected anticoagulation therapy can help to reduce the medical costs of patients suffering from atrial fibrillation. A new study from the University of Eastern Finland shows that direct oral anticoagulants can be a more cost-effective alternative than traditional warfarin therapy when the patient's place of residence is taken into consideration.

27 Nov 2019

Researchers create new coating to prevent clotting, infection in synthetic vascular grafts

Researchers at McMaster University have created a new coating to prevent clotting and infection in synthetic vascular grafts, while also accelerating the body's own process for integrating the grafted vessels.

27 Nov 2019

Clinical benefit of anticoagulants for atrial fibrillation decreases with age, shows study

The net clinical benefit of anticoagulants for atrial fibrillation (AF) -- one of the most important causes of irregular heartbeats and a leading cause of stroke -- decreases with age, as the risk of death from other factors diminishes their benefit in older patients, according to a study led by researchers at UC San Francisco.

11 Nov 2019

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