in vitro News and Research

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If you’re poor, fertility treatment can be out of reach

Mary Delgado's first pregnancy went according to plan, but when she tried to get pregnant again seven years later, nothing happened. After 10 months, Delgado, now 34, and her partner, Joaquin Rodriguez, went to see an OB-GYN.

26 Feb 2024

Study reveals how long COVID can affect brain function through vascular disruption

The neurological response to coronavirus disease 2019 (COVID-19) may be due to brain-brain barrier (BBB) disruption.

26 Feb 2024

Study links ultra-processed foods to gut health risks

A review in Nature Reviews Gastroenterology & Hepatology synthesizes evidence on the negative impacts of ultra-processed foods and food additives on gut health, linking them to chronic diseases and alterations in the gut microbiome.

25 Feb 2024

ACMG releases new Points to Consider statement on the clinical utility of polygenic risk scores for embryo selection

Should we be using polygenic risk score assessment for embryo selection? Providing in-depth analysis, the Social, Ethical and Legal Issues Committee of the American College of Medical Genetics and Genomics (ACMG) has released a new Points to Consider statement to assist healthcare professionals and patients in understanding the safety and utility of preimplantation genetic testing for polygenic disorders (PGT-P) as a clinical service.

23 Feb 2024

Natural killer cells lead the charge in cancer treatment innovation

Review synthesizes research on NK cells' role in cancer immunity and their potential in therapeutics through bioengineering, immune checkpoint inhibitors, and cell engagers, highlighting ongoing preclinical and clinical trials.

22 Feb 2024

Diets impact Parkinson's motor symptoms, supplements show no benefit, study finds

Meta-analysis reveals that diets like the Mediterranean and ketogenic can improve motor function in Parkinson's disease patients, although dietary supplements do not enhance UPDRS or 6MWT scores.

21 Feb 2024

“Laboratory testicles” could solve male infertility mysteries

The testis is responsible for sperm production and testosterone synthesis. Abnormalities in testis development and function lead to disorders of sex development (DSD) and male infertility. Currently, no in vitro system exists for modeling the testis.

20 Feb 2024

New model pinpoints drug interactions in the digestive tract

Any drug that is taken orally must pass through the lining of the digestive tract. Transporter proteins found on cells that line the GI tract help with this process, but for many drugs, it's unknown which of those transporters they use to exit the digestive tract.

20 Feb 2024

Study suggests high levels of vitamin B3 breakdown products are linked to higher risk of mortality, heart attacks, and stroke

Researchers utilized an untargeted metabolomics technique to look for new compounds and pathways that may contribute to residual cardiovascular disease risk.

19 Feb 2024

Cellectricon’s expertise in pain research recognized by second EU research grant

BonePainIII project will support an early-stage researcher in quest for novel mechanistic insight and potential therapeutic targets.

From Cellectricon 19 Feb 2024

Research demonstrates a bat species' resistance to cancer, pinpoints key genes

A study reveals Myotis pilosus bats exhibit exceptional cancer resistance through gene downregulation, offering insights into natural anticancer mechanisms.

18 Feb 2024

Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

15 Feb 2024

GV1001 exerts anti-aging effects in triple transgenic Alzheimer's mice

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 3, entitled, "GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects."

15 Feb 2024

Breaking through new research barriers with iPSC technology

In this interview, we speak to Keith Olson and Coby Carlson from Fujifilm Cellular Dynamics about their iPSC technology.

From FUJIFILM Cellular Dynamics 15 Feb 2024

Extract from pomegranate peels and seeds shows anti-hypertensive properties

The efficacy of an extract obtained from the non-edible parts of pomegranates.

14 Feb 2024

How does melanin distribution impact UV damage?

How melanin content and distribution affect ultraviolet damage in skin.

14 Feb 2024

Study finds interleukin-24 enhances CAR-T cell therapy's effectiveness against cancer stem cells

The effect of Interleukin-24 (IL-24) on CSCs and CAR-T cell therapy.

14 Feb 2024

Beyond just a berry: The multifaceted health benefits of black chokeberry

Review highlights the potential of black chokeberry (Aronia melanocarpa) in disease control and prevention, focusing on its rich polyphenol content and the diverse mechanisms through which it exerts anti-disease properties on the human body.

12 Feb 2024

Olive oil's secret weapon against Alzheimer's: phenolic compounds

A comprehensive review in the International Journal of Molecular Sciences highlights the potential of extra-virgin olive oil and its phenolic compounds in preventing and treating Alzheimer's disease through various mechanisms, including reducing amyloid-beta accumulation and neuroinflammation.

12 Feb 2024

Novel approach improves CAR T-cell therapy efficacy against acute myeloid leukemia

St. Jude Children's Research Hospital scientists improved chimeric antigen receptor (CAR) T–cell immunotherapy for acute myeloid leukemia (AML), demonstrating better efficacy in the lab.

12 Feb 2024