Sysmex CN-3000 and CN-6000 Systems for hemostasis testing

The CN-3000 and CN-6000 Systems¹ are small-scale, mid-, and high-volume hemostasis testing solutions that can handle large lab challenges.

The CN-3000 and CN-6000 Systems¹ were designed with smart workflow features and a small footprint to assist laboratories in meeting today’s testing challenges. These versatile systems, which support a wide range of testing methodologies, such as clotting, chromogenic, immunoassay, and aggregation, facilitate testing consolidation in mid- and high-volume labs.

Features and benefits

Where size, speed, intelligence, and flexibility combine to accelerate hemostasis workflows

The CN-3000 and CN-6000 Systems¹ are mid- and high-volume coagulation analyzers that are completely automated. They are as follows:

Smaller

Image Credit: Siemens Healthineers

The smallest footprint that is obtainable in the hemostasis market.²

Faster

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450 PT tests per hour—the quickest throughput in the industry.³

Smarter

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Intelligent workflow functionalities and artificial intelligence (AI) combine to create our most intelligent hemostasis analyzers yet.⁴

More flexible

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Options for mid- and high-volume throughput and a wide range of automation options.

The Sysmex CN-6000 System has improved our workflow and enabled us to deliver results faster. Since sample analysis ends once the clot is formed, we can obtain results faster. Other hemostasis systems continue analysis for 180 seconds regardless of the clot formation.”

Dr José Luis Bedini, Head, Core Lab Operative Area Hospital, Clínic de Barcelona

Take a tour of the system features

The CN Systems¹ combine optical testing methodology with intelligent software to automate and standardize sample management, resulting in more consistent results, fewer repeat tests, and less reagent waste. The systems deliver what laboratories need to support a wide variety of testing profiles and space requirements, with the versatility to endorse mid- or high-volume throughput needs to continue operating as stand-alone analyzers or to connect to automation.

Smart workflow features help staff plan daily requirements and reduce interruptions

• For a smarter workflow and fewer interruptions, the system provides algorithmic calculation of the number of tests onboard and scheduled per day
• The reagents and consumables home screen condenses daily workload data into a single, actionable dashboard
• For continuous and uninterrupted multiwavelength scanning, the smart LED light source has a lifespan of up to five years.

Image Credit: Siemens Healthineers

Sophisticated operating system detects potential issues before they become problems and guides troubleshooting

• The system detects impediments and advises the operator on corrective actions
• Intelligent sample flag management and guidance assist technicians in identifying and resolving issues quickly
• Advanced audit trails improve traceability, including consumables and error detection

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Platelet aggregation testing⁵ supports advanced patient assessments

• Integrating platelet aggregation⁵ testing streamlines and automates the diagnosis of platelet disorders.
• Clot waveform analysis (CWA)⁶ offers qualitative, sensitive waveform patterns by illustrating the optical reaction profile during PT or APTT measurement.
• Multidilution analysis (MDA) automated mixing studies offer data and guidance to clinicians concerning factor inadequacies and circulating inhibitor patterns.

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Scalability and standardization for high-performance hemostasis testing in various testing environments

• Mid-volume instrument connectivity to the lab automation system (LAS) means more options for right-sizing the hemostasis workflow.
• Single-discipline and multi-disciplinary automation is supported by Aptio® Automation, FlexLab Automation, and other third-party solutions.
• Point-in-space sampling enables rapid throughput

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Small footprint with rapid throughput enhances productivity per square meter

• The smallest hemostasis testing system on the market²

• Concurrent sample loading from both the track and the front of the system for flexible testing options and augmented STAT management

• An optional sampler expands capacity

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Advanced preanalytical sample quality checks and smart sample management provide confidence in results

• The system detects and handles inappropriate samples to decrease retests and reflex testing.
• For the evaluation of fragile clots, optical methodology displays clot formation.
• To prevent sample waste, smart PSI^® technology detects and uses common aliquot.
• Gain-switching technology allows for precise testing and reporting of samples with high levels of interference, such as highly lipemic samples.

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Streamlined security, maintenance, and user access enable operational efficiency

• System startup and backup automation make routine tasks easier
• Logging in with a contactless smart card streamlines workflow and shift changes
• Automatic screen locking and user-defined access levels aid in ensuring the integrity of the results and reducing the risk of user error
• Simple daily maintenance procedures (less than five minutes per day with ready-to-use cleaning solution) reduce downtime and increase uptime

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Assays

The CN-3000 and CN-6000 Systems¹ offer an expansive test menu of routine and specialty hemostasis assays—including several INNOVANCE^® assays—all on a single instrument, allowing labs to run more tests per sample while processing a higher number of samples.

The cooled reagent storage (4–12°C) contains 38 positions for reagents, controls, and calibrators as well as 6 buffer solution positions. Image Credit: Siemens Healthineers

Technical specifications

Expand the knowledge of the CN-3000 and CN-6000¹ systems’ key specifications and differences.

Dimensions

Table 1. Source: Siemens Healthineers 

Measurement channels

Table 2. Source: Siemens Healthineers 

Sample capacity

Table 3. Source: Siemens Healthineers 

Throughput (tests/hour, approx.)

Table 4. Source: Siemens Healthineers 

Numbers are for normal-mode processing. Throughput values were determined by the time to first result; processing capability varies depending on the reagent used. Throughput values stated above were determined using Sysmex study protocol with PT (Thromborel^® S assay), APTT (Pathromtin^® SL assay), INNOVANCE D-Dimer assay, and AT (INNOVANCE Antithrombin assay) test applications.

Operation

Table 5. Source: Siemens Healthineers 

Reaction tubes

Table 6. Source: Siemens Healthineers 

Traceability

Table 7. Source: Siemens Healthineers 

Automation

Table 8. Source: Siemens Healthineers

Optimized digital solutions

Whether hemostasis is fully integrated or stand-alone, Siemens Healthineers offers a wide range of digital solutions that help to optimize clinical operations.

Atellica Data Manager

Laboratory data management software to standardize testing and streamline result management throughout the lab and across your diagnostic network.

Atellica Process Manager

Combines a centralized command center with built-in analytics so labs can better control and optimize processes.

Atellica Inventory Manager

Real-time automated inventory management that automates control of reagents and consumables across multiple locations to reduce costs, save time, and improve lab quality

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1 The products/features/applications mentioned here are not commercially available in all countries and are subject to local regulations. Their future availability cannot be guaranteed. Not available for sale in the U.S.

2 As of January 2024. Footprint compared to competitor systems in the same volume class as listed on https://www.captodayonline.com/ and in the COBAS T 511 and COBAS T 711 coagulation analyzers brochure, Roche, 2018, and sthemO 301 analyzer brochure, Stago, 2023.

3 As of January 2024. CN-6000 System throughput: 400 PT/APTT; CN-3000 System throughput: 215 PT/APTT. Throughput evaluated against systems in the same volume class as listed on https://www.captodayonline.com/ and in the COBAS T 511 and COBAS T 711 coagulation analyzers brochure, Roche, 2018. No throughput data available for sthemO 301 analyzer.

4 As of January 2024.

5 The products/features are not commercially available in all countries. Due to regulatory reasons, their future availability cannot be guaranteed. Please contact your local Siemens Healthineers organization for further details. In the U.S., platelet aggregation testing is for research use only, not for use in diagnostic procedures.

6 Research use only.

CN-3000 and CN-6000 Systems refer to Automated Blood Coagulation Analyzer CN-3000 and Automated Blood Coagulation Analyzer CN-6000 respectively. CN Systems refers to Automated Blood Coagulation Analyzer CN-3000 and Automated Blood Coagulation Analyzer CN-6000.

Aptio, Atellica, INNOVANCE, Pathromtin, PSI, Thromborel, and all associated marks are trademarks of Siemens Healthcare Diagnostics Inc., or its affiliates. Aptio Automation is manufactured by Inpeco SA and is exclusively distributed by Siemens Healthcare Diagnostics Inc. All other trademarks and brands are the property of their respective owners.

Product availability may vary from country to country and is subject to varying regulatory requirements. Please contact your local representative for availability.